Abstract
Scopolamine patch was evaluated for the prevention of post-operative emesis in 50 children undergoing strabismus surgery. All subjects were premeditated, with none receiving narcotic premedicants. Anaesthesia included controlled ventilation with the use of muscle relaxants, atropine, and halothane. Before operation, the subjects were randomly assigned to one of two groups: a treatment group received a scopolamine patch at a dose of either 0.75 mg or 0.375 mg, and a control group received no patch. Both the incidence and frequency of vomiting in the scopolamine-treated group were significantly (P < 0.05) lower than in the control group.
Résumé
Une patch de scopolamine fut évaluée pour la prévention du vomissement postopératoire chez cinquante enfants subissant une chirurgie pour strabisme. Tous les sujets furenl prémé-diqués mais aucun d’eux n’a reçu de prémédications an narcotique. L’anesthésie fut. conduite sous une ventilation contrôlée utilisant des relaxants musculaires, de iatropine et de l’halothane. Avant l’opération, les sujets furent randomisés en deux groupes: un groupe ayant reçu les traitements avec la scopolamine patch à une dose soil de 0,75 mg ou 0,375 mg, et un groupe contrôle n’avant reçu aucun traitemenl. L’incidence et la fréquence des vomissemenls dans le groupe traité avec la scopolamine furent significativement (P < 0.05) plus basses que le groupe contrôle.
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Horimoto, Y., Tomie, H., Hanzawa, K. et al. Scopolamine patch reduces postoperative emesis in paediatric patients following strabismus surgery. Can J Anaesth 38, 441–444 (1991). https://doi.org/10.1007/BF03007580
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DOI: https://doi.org/10.1007/BF03007580