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Phytotherapeutic potential and pharmaceutical impact of Phoenix dactylifera (date palm): current research and future prospects

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Abstract

Phoenix dactylifera (date palm) is a member of the genus Phoenix belonging to family Arecaceae. It is widely cultivated for its edible fruits and kernels. Dates have been used for both dietary purposes as well as for their phytomedicinal impacts against the variety of diseases. Date fruits are rich in alkaloids, protein, carbohydrate, fatty acid (linoleic, lauric, palmitic, and stearic acid), carotenoids, vitamins, polyphenolic compounds, flavonoids, and tannins along with different types of nutrients like potassium, calcium, magnesium, and phosphorus. Due to the presence of the variety of phytochemicals, they have greater impact on human health. They have strong antioxidant potential. It has been proposed now as a potential source of several unique medical and industrial products. In literature, much information is available on botanical descriptions, agriculture technology, and utilization in therapeutic intervention, but a little description is accessible on phytochemical relevance, formulation strategies, nutritional impact, and bioprocess technology. Therefore, the present review provides comprehensive information on the phytochemical relevance, pharmacology/bioactivity, pharmaceutical impact, their scope in bioprocess technology and nutraceutical values of date palm. According to all collected information, every portion of the plant has some beneficial properties that can serve as a source of medicine and nutraceutical.

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Abbreviations

PD:

Phoenix dactylifera

DP:

Date palm

DSO:

Date seed oil

DM:

Diabetes mellitus

FAO:

Food and agriculture organization

GCC:

Gulf cooperation council

HPLC–DAD-ESI-MS:

High performance liquid chromatography-diode array detection-electrospray ionization-mass spectrometry

SmF:

Submerged fermentation

SSF:

Solid state fermentation

SLF:

Slurry state fermentation

UV:

Ultra violet spectroscopy

ZnO-NPs:

Zinc oxide nanoparticles

USFDA:

United States Food and drug administration

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Acknowledgements

“The authors are thankful to King Saud University, Vice Deanship of Research Chairs, Kayyali Chair for Pharmaceutical industries for constant support in manuscript writing and scientific suggestions through the Grant No. FN-2018”.

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Authors and Affiliations

  1. Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India

    Abdul Qadir

  2. Kayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia

    Faiyaz Shakeel

  3. Department of Science, Jamia Hamdard (Hamdard University), New Delhi, 110062, India

    Athar Ali

  4. Tetri Chandravansi Pharmacy College, Ramchandra Chandravansi University, Bishrampur, Palamu, Jharkhand, 822124, India

    Md. Faiyazuddin

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  1. Abdul Qadir
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  4. Md. Faiyazuddin
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Correspondence to Faiyaz Shakeel.

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Qadir, A., Shakeel, F., Ali, A. et al. Phytotherapeutic potential and pharmaceutical impact of Phoenix dactylifera (date palm): current research and future prospects. J Food Sci Technol 57, 1191–1204 (2020). https://doi.org/10.1007/s13197-019-04096-8

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