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Nanomaterials-assisted thermally induced neuromodulation

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Abstract

Neuromodulation, as a fast-growing technique in neuroscience, has been a great tool in investigation of the neural pathways and treatments for various neurological disorders. However, the limitations such as constricted penetration depth, low temporal resolution and low spatial resolution hindered the development and clinical application of this technique. Nanotechnology, which refers to the technology that deals with dimension under 100 nm, has greatly influenced the direction of scientific researches within recent years. With the recent advancements in nanotechnology, much attention is being given at applying nanomaterials to address the limitations of the current available techniques in the field of biomedical science including neuromodulation. This mini-review aims to introduce the current state-of-the-art stimuli-responsive nanomaterials used for assisting thermally induced neuromodulation.

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Acknowledgements

This study was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF-2020R1C1C1007589), Korea Medical Device Development Fund grant funded by the Korean government (Ministry of Science and ICT, Ministry of Trade, Industry and Energy, Ministry of Health & Welfare, Ministry of Food and Drug Safety) (NTIS no. 9991006805), National R&D Program through the National Research Foundation of Korea (NRF) funded by Ministry of Science and ICT (2021M3H4A1A03048648/2021M3F3A2A01037365), the Smart Project Program through KAIST–Khalifa Joint Research Center (KK-JRC), KAIST College of Engineering Global Initiative Convergence Research Program, KI Meta Convergence Research Program, and KAIST Post-AI Research Project.

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Authors and Affiliations

  1. Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea

    Congqi Yang & Seongjun Park

  2. KAIST Institute for Health Science and Technology (KIHST), Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea

    Seongjun Park

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  1. Congqi Yang
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Correspondence to Seongjun Park.

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Yang C declares that s/he has no conflict of interest in relation to the work in this article. Park S declares that s/he has no conflict of interest in relation to the work in this article.

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Yang, C., Park, S. Nanomaterials-assisted thermally induced neuromodulation. Biomed. Eng. Lett. 11, 163–170 (2021). https://doi.org/10.1007/s13534-021-00193-w

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