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Complications of Severe Mental Illness Related to Alcohol and Drug Use Disorders

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Recent Developments in Alcoholism

Part of the book series: Recent Developments in Alcoholism ((RDIA,volume 14))

Abstract

In this chapter we review research on the relationships between substance use disorder and 11 domains of adjustment for people with severe mental illness. Studies are divided into correlational research and prospective, longitudinal research, with greater weight given to those in the latter category. The weight of the evidence indicates that substance abuse severely complicates severe mental illness in the following domains: relapse of psychiatric illness, hospitalization, disruptive behavior, familial problems, residential instability, decreased functional status, HIV infection, and medication noncompliance. We discuss the limits of causal inference in these studies and the possible mechanisms that relate substance abuse to various complications.

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References

  1. Barry K, Fleming M, Greenley J, et al: Characteristics of persons with severe mental illness and substance abuse in rural areas. Psychiatric Serv 47:88–90, 1996.

    CAS  Google Scholar 

  2. Comtois K, Ries R, Armstrong H: Case manager ratings of the clinical status of dually diagnosed outpatients. Hosp Commun Psychiatry 45:568–573, 1994.

    CAS  Google Scholar 

  3. Lehman AF, Myers C, Corty E, et al: Prevalence and patterns of “dual diagnosis” among psychiatric inpatients. Compr Psychiatry 35:106–112, 1994.

    Article  PubMed  CAS  Google Scholar 

  4. Mueser KT, Yarnold P, Bellack A: Diagnostic and demographic correlates of substance abuse in schizophrenia and major affective disorder. Acta Psychiatr Scand 85:48–55, 1992.

    PubMed  CAS  Google Scholar 

  5. Mueser KT, Yarnold P, Levinson D, et al: Prevalence of substance abuse in schizophrenia: Demographic and clinical correlates. Schizophr Bull 16:31–56, 1990.

    PubMed  CAS  Google Scholar 

  6. Warner R, Taylor D, Wright J, et al: Substance use among the mentally ill: Prevalence, reasons for use, and effects on illness. Am J Orthopsychiatry 64:30–39, 1994.

    PubMed  CAS  Google Scholar 

  7. Regier D, Myers J, Kramer M, et al: The NIMH epidemiologic catchment area study: Historical context, major objectives, and study population characteristics. Arch Gen Psychiatry 91:934–941, 1984.

    Google Scholar 

  8. Boyd J, Burke J, Gruenburg E, et al: Exclusion criteria of DSM-III: A study of co-occurrence of hierarchy-free syndromes. Arch Gen Psychiatry 41:983–989, 1984.

    PubMed  CAS  Google Scholar 

  9. Lehman AF, Myers C, Dixon L, et al: Detection of substance use disorders among psychiatric inpatients. JNerv Ment Dis 184:228–233, 1996.

    CAS  Google Scholar 

  10. Toner B, Gillies L, Prendergast P, et al: Substance use disorders in a sample of Canadian patients with chronic mental illness. Hosp Commun Psychiatry 43:251–254, 1992.

    CAS  Google Scholar 

  11. Dixon L, Gaas G, Weiden P, et al: Acute effects of drug abuse in schizophrenic patients. Schizophr Bull 16:69–79, 1990.

    PubMed  CAS  Google Scholar 

  12. Barbee JG, Clark PD, Crapanzano MS, et al: Alcohol and substance abuse among schizophrenic patients presenting to an emergency psychiatric service. J Nerv Ment Dis 177:400–407, 1989.

    PubMed  CAS  Google Scholar 

  13. Cleghorn JM, Kaplan RD, Szechtman B, et al: Substance abuse and schizophrenia: Effect on symptoms but not on neurocognitive function. J Clin Psychiatry 52:26–30, 1991.

    PubMed  CAS  Google Scholar 

  14. Drake RE, Osher FC, Wallach MA: Alcohol use and abuse in schizophrenia: A prospective community study. J New Ment Dis 177:408–414, 1989.

    CAS  Google Scholar 

  15. Duke PJ, Pantelis C, Barnes TRE: South Westminster schizophrenia survey: Alcohol use and its relationship to symptoms, tardive dyskinesia, and illness onset. Brit J Psychiatry 161:630–636, 1994.

    Google Scholar 

  16. Negrete JC, Knapp WP, Douglas DE, et al: Cannabis affects the severity of schizophrenic symptoms: Result of a clinical survey. Psychol Med 16:515–520, 1986.

    Article  PubMed  CAS  Google Scholar 

  17. Osher FC, Drake RE, Noordsy DL, et al: Correlates and outcomes of alcohol use disorder among rural outpatients with schizophrenia. J Clin Psychiatry 55:109–113, 1994.

    PubMed  CAS  Google Scholar 

  18. Pulver AE, Wolyniec PS, Wagner MG, et al: An epidemiologic investigation of alcohol-dependent schizophrenics. Acta Psychiatr Scand 79:603–612, 1989.

    PubMed  CAS  Google Scholar 

  19. Soni SD, Brownlee M: Alcohol abuse in chronic schizophrenics: Implications for management in the community. Acta Psychiatr Scand 84:272–276, 1991.

    PubMed  CAS  Google Scholar 

  20. Alterman AI, Erdlen DL, Laporte DJ, et al: Effects of illicit drug use in an inpatient psychiatric population. Addict Behav 7:231–242, 1982.

    PubMed  CAS  Google Scholar 

  21. Brunette MF, Mueser KT, Xie H, et al: Relationships between symptoms of schizophrenia and substance abuse. J Nerv Ment Dis 185:13–20, 1997.

    PubMed  CAS  Google Scholar 

  22. Carey MP, Carey KB, Meisler AW: Psychiatric symptoms in mentally ill chemical abusers. J Nerv Ment Dis 179:136–138,1991.

    PubMed  CAS  Google Scholar 

  23. Cuffel BJ, Heithoff KA, Lawson W: Correlates of patterns of substance abuse among patients with schizophrenia. Hosp Commun Psychiatry 44:247–251, 1993.

    CAS  Google Scholar 

  24. Kovasznay B, Bromet E, Schwartz JE, et al: Substance abuse and onset of psychotic illness. Hosp Commun Psychiatry 44:567–571,1993.

    CAS  Google Scholar 

  25. Lysaker P, Bell M, Beam-Goulet J: Relationship of positive and negative symptoms to cocaine abuse in schizophrenia. J New Ment Dis 182:109–112, 1994.

    CAS  Google Scholar 

  26. Peralta V, Cuesta MJ: Influence of cannabis abuse on schizophrenic psychopathology. Acta Psychiatr Scand 85:127–130, 1992.

    PubMed  CAS  Google Scholar 

  27. Rosenthal RN, Hellerstein DJ, Miner CR: Positive and negative syndrome typology in schizophrenic patients with psychoactive substance use disorders. Compr Psychiatry 35:91–98, 1994.

    Article  PubMed  CAS  Google Scholar 

  28. Sanguineti VR, Samuel S: Comorbid substance abuse and recovery from acute psychiatric relapse. Hosp Commun Psychiatry 44:1073–1078,1993.

    CAS  Google Scholar 

  29. Serper MR, Alpert M, Richardson NA, et al: Clinical effects of recent cocaine use on patients with acute schizophrenia. Am J Psychiatry 152:1464–1469, 1995.

    PubMed  CAS  Google Scholar 

  30. Sevy S, Kay SR, Opler LA, et al: Significance of cocaine history in schizophrenia. J Nerv Ment Dis 178:642–648, 1990.

    PubMed  CAS  Google Scholar 

  31. Swofford CD, Kasckow JW, Scheller-Gilkey G, et al: Substance use: A powerful predictor of relapse in schizophrenia. Schizophr Res 20:145–151, 1996.

    Article  PubMed  CAS  Google Scholar 

  32. Tsuang JW, Lohr JB: Effects of alcohol on symptoms in alcoholic and nonalcoholic patients with schizophrenia. Hosp Commun Psychiatry 45:1229–1230, 1994.

    CAS  Google Scholar 

  33. Buckley P, Thompson P, Way L, et al: Substance abuse among patients with treatment-resistant schizophrenia: Characteristics and implications for clozapine therapy. Am J Psychiatry 151:385–389, 1994.

    PubMed  CAS  Google Scholar 

  34. Kirkpatrick B, Amador XR, Flaum M, et al: The deficit syndrome in the DSM-IV field trial: I. Alcohol and other drug abuse. Schizophr Res 20:69–77, 1996.

    PubMed  CAS  Google Scholar 

  35. Dixon LB, Haas G, Weiden PJ, et al: Drug abuse in schizophrenic patients: Clinical correlates and reasons for use. Am J Psychiatry 148:224–230, 1991.

    PubMed  CAS  Google Scholar 

  36. Linszen DH, Dintgemans PM, Lenior ME: Cannabis abuse and the course of recent-onset schizophrenic disorders. Arch Gen Psychiatry 51:273–279, 1994.

    PubMed  CAS  Google Scholar 

  37. Alterman AI, Erdlen FR, McLellan AT, et al: Problem drinking in hospitalized schizophrenic patients. Addict Behav 5:273–276,1980.

    Article  PubMed  CAS  Google Scholar 

  38. Brady KT, Anton R, Ballenger JC, et al: Cocaine abusing among schizophrenic patients. Am J Psychiatry 147:1164–1167, 1990.

    PubMed  CAS  Google Scholar 

  39. Menezes PR, Johnson S, Thornicroft G, et al: Drug and alcohol problems among individuals with severe mental illnesses in South London. Br J Psychiatry 168:612–619, 1996.

    PubMed  CAS  Google Scholar 

  40. Tsuang MT, Simpson JC, Kronfol Z: Subtypes of drug abuse with psychosis. Arch Gen Psychiatry 39:141–147, 1982.

    PubMed  CAS  Google Scholar 

  41. Alterman AI, Ayre FR, Williford WO: Diagnostic validation of conjoint schizophrenia and alcoholism. J Clin Psychiatry 45:300–303,1984.

    PubMed  CAS  Google Scholar 

  42. Gupta S, Hendricks S, Kenkel AM, et al: Relapse in schizophrenia: Is there a relationship to substance abuse? Schizophr Res 20:153–156, 1996.

    Article  PubMed  CAS  Google Scholar 

  43. Haywood TW, Kravitz HM, Grossman LS, et al: Predicting the “revolving door” phenomenon among patients with schizophrenic, schizoaffective, and affective disorders. Am J Psychiatry 152:856–861, 1995.

    PubMed  CAS  Google Scholar 

  44. Kutcher S, Kachur E, Marton P, et al: Substance abuse among adolescents with chronic mental illnesses: A pilot study of descriptive and differentiating features. Can J Psychiatry 37:428–431, 1992.

    PubMed  CAS  Google Scholar 

  45. Safer D: Substance abuse by young adult chronic patients. Hosp Commun Psychiatry 38:511–514,1987.

    CAS  Google Scholar 

  46. Soyka M, Albus M, Kathmann N, et al: Prevalence of alcohol and drug abuse in schizophrenic patients. Eur Arch Psychiatry Clin Neurosci 242:362–372, 1993.

    Article  PubMed  CAS  Google Scholar 

  47. Kashner TM, Rader LE, Rodell DE, et al: Family characteristics, substance abuse, and hospitalization patterns of patients with schizophrenia. Hosp Commun Psychiatry 42:195–197, 1991.

    CAS  Google Scholar 

  48. Cuffel BJ, Chase P: Remission and relapse of substance use disorder in schizophrenia: Results from a one-year prospective study. J Nerv Ment Dis 182:542–348, 1994.

    Google Scholar 

  49. Shaner A, Eckman TA, Roberts LJ, et al: Disability income, cocaine use and repeated hospitalization among schizophrenic cocaine abusers: A government sponsored revolving door? New Engl J Med 333:377–783, 1995.

    Article  Google Scholar 

  50. Martinez-Arevalo MJ, Calcedo-Ordonez A, Varo-Prieto JR: Cannabis consumption as a prognostic factor in schizophrenia. Br J Psychiatry 164:679–681, 1994.

    Article  PubMed  CAS  Google Scholar 

  51. Craig TJ, Lin SP, El-Defrawi MH, et al: Clinical correlates of readmission in a schizophrenic cohort. Psychiatric Q 575–10, 1985.

    Google Scholar 

  52. Drake RE, Wallach MA: Substance abuse among the chronic mentally ill. Hosp Commun Psychiatry 40:1041–1046, 1989.

    CAS  Google Scholar 

  53. Fischer EP, Owen RR, Cuffel BJ: Substance abuse, community service use, and symptom severity of urban and rural residents with schizophrenia. Psychiatric Serv 47:980–984, 1996.

    CAS  Google Scholar 

  54. Khantzian EJ: The self-medication hypothesis of addictive disorders: Focus on heroin and cocaine dependence. Am J Psychiatry 142:1259–1264, 1985.

    PubMed  CAS  Google Scholar 

  55. Hamera E, Schneider JK, Deviney S: Alcohol, cannabis, nicotine, and caffeine use and symptom distress in schizophrenia. J Nerv Ment Dis 183:559–565, 1995.

    PubMed  CAS  Google Scholar 

  56. Bartels SJ, Drake RE, Wallach MA, et al: Characteristic hostility in schizophrenic outpatients. Schizophr Bull 17:163–171, 1991.

    PubMed  CAS  Google Scholar 

  57. Blomhoff S, Seim S, Friis S: Can prediction of violence among psychiatric inpatients be improved? Hosp Commun Psychiatry 41:771–775, 1990.

    CAS  Google Scholar 

  58. Cuffel BJ: Violent and destructive behavior among the severely mentally ill in rural areas: Evidence from Arkansas’ community mental health system. Commun Ment Health J 30:495–504, 1994.

    CAS  Google Scholar 

  59. Kozaric-Kovadc D, Folnegovic-Smalc V, Folnegovic Z, et al: Influence of alcoholism on the prognosis of schizophrenic patients. J Stud Alcohol 56:622–627, 1995.

    Google Scholar 

  60. Richardson MA, Craig TJ, Haugland G: Treatment patterns of young chronic schizophrenic patients in the era of deinstitutionalization. Psychiatric Q 57:104–110, 1985.

    CAS  Google Scholar 

  61. Swanson JW, Holzer CE, Ganju VK, et al: Violence and psychiatric disorder in the community: Evidence from the Epidemiologic Catchment Area Survey. Hosp Commun Psychiatry 41:761–770, 1990.

    CAS  Google Scholar 

  62. Yesavage JA, Zarcone V: History of drug abuse and dangerous behavior in inpatient schizophrenics. J CIin Psychiatry 44:259–261, 1983.

    CAS  Google Scholar 

  63. Convit A, Nemes ZC, Volavka J: History of phencyclidine use and repeated assaults in newly admitted young schizophrenic men. Am J Psychiatry 145:1176, 1988.

    PubMed  CAS  Google Scholar 

  64. Cuffel BJ, Shumway M, Choulijian TL, et al: A longitudinal study of substance abuse and community violence in schizophrenia. J Nerv Ment Dis 182:704–708, 1994.

    PubMed  CAS  Google Scholar 

  65. Kay SR, Wolkenfeld F, Murrill LM: Profiles of aggression among psychiatric patients II. Covariates and predictors. J Nerv Ment Dis 39:547–557, 1988.

    Google Scholar 

  66. Link BG, Cullen FT, Andrews H: The violent and illegal behavior of mental patients reconsidered. Am Soc Rev 57:275–292, 1992.

    Google Scholar 

  67. Monahan J: Mental disorder and violent behavior: Perceptions and evidence. Am Psychol 47:511–521, 1992.

    Article  PubMed  CAS  Google Scholar 

  68. Mueser KT, Rosenberg SD, Drake RE, et al: Antisocial personality disorder and substance abuse in schizophrenia and major affective disorders. J Stud Alcohol, in press.

    Google Scholar 

  69. Abram KM, Teplin LA: Co-occurring disorders among mentally ill jail detainees. Am Psychol 46:1036–1045, 1991.

    Article  PubMed  CAS  Google Scholar 

  70. Chiles JA, Von Cleve E, Jemelka RP, et al: Substance abuse and psychiatric disorders in prison inmates. Hosp Commun Psychiatry 41:1132–1134, 1990.

    CAS  Google Scholar 

  71. Lindqvist P, Allebeck P: Schizophrenia and assaultive behavior: The role of alcohol and drug abuse. Acta Psychiutr Scand 82:191–195, 1989.

    Google Scholar 

  72. Regier DA, Farmer ME, Rae DE, et al: Comorbidity of mental disorders with alcohol and other drug abuse. JAMA 264:2511–2518, 1990.

    Article  PubMed  CAS  Google Scholar 

  73. Wessely SC, Castle D, Douglas AJ, et al: The criminal careers of incident cases of schizophrenia. Psychol Med 224:483–502, 1994.

    Google Scholar 

  74. Zitrin A, Hardesty AS, Burdock EI, et al: Crime and violence among mental patients. Am J Psychiatry 133:142–149, 1976.

    PubMed  CAS  Google Scholar 

  75. Cohen E, Henkin I: Prevalence of substance abuse by seriously mentally ill patients in a partial hospital program. Hosp Commun Psychiatry 44:178–180, 1993.

    CAS  Google Scholar 

  76. Tardiff K, Marzuk PM, Leon AC, et al: Violence by patients admitted to a private psychiatric hospital. Am JPsychiatry 154:88–93, 1997.

    CAS  Google Scholar 

  77. Taylor PJ: Motives for offending among violent and psychotic men. Br J Psychiatry 147:491–498,1985.

    PubMed  CAS  Google Scholar 

  78. Drake RE, Gates C, Whitaker A, et al: Suicide among schizophrenics: A review. Compr Psychiatry 26:90–100, 1985.

    Article  PubMed  CAS  Google Scholar 

  79. Achte KA, Stenback A, Teravainen H: On suicides committed during treatment in psychiatric hospitals. Acta Psychiatr Scand 42:272–284, 1966.

    PubMed  CAS  Google Scholar 

  80. Bartels SJ, Drake RE, McHugo G: Alcohol use, depression and suicidal behavior in schizophrenia. Am J Psychiatry 149:394–395,1992.

    PubMed  CAS  Google Scholar 

  81. Dassori AM, Mezzich JE, Keshavan M: Suicidal indicators in schizophrenia. Acta Psychiatr Scand 81:409–413, 1990.

    PubMed  CAS  Google Scholar 

  82. Kay SR, Kalathara M, Meinzer AE: Diagnostic and behavioral characteristics of psychiatric patients who abuse substances. Hosp Commun Psychiatry 40:1061–1064, 1989.

    Google Scholar 

  83. Noriek K: Attempted suicide and suicide in functional psychoses. Acta Psychiatr Scand 52:81–106,1975.

    Google Scholar 

  84. Sletten I, Brown M, Evenson R, et al: Suicide in mental hospital patients. Dis Nerv Sys 33:328–334, 1972.

    CAS  Google Scholar 

  85. Tardiff K, Sweillam A: Assault, suicide, and mental illness. Arch Gen Psychiatry 37:164–169, 1980.

    PubMed  CAS  Google Scholar 

  86. Allebeck P, Varla A, Kristjansson E, et al: Risk factors for suicide among patients with schizophrenia. Acta Psychiutr Scand 76:414–419,1987.

    CAS  Google Scholar 

  87. Drake RE, Gates CG, Cotton PG, et al: Suicide among schizophrenics: Who is at risk? J Nerv MentDis 172:613–617, 1984.

    CAS  Google Scholar 

  88. Schaffer JW, Perlin S, Schmidt CW, et al: The prediction of suicide in schizophrenia. J Nerv MentDis 159:349–355,1974.

    Google Scholar 

  89. Sins SG, Kane JM, Frechen K, et al: Histones of substance abuse in patients with post-psychotic depressions. Compr Psychiatry 29:550–557, 1993.

    Google Scholar 

  90. Westermeyer JF, Harrow M, Marengo J: Risk for suicide in schizophrenia and other psychotic and nonpsychotic disorders. J Nerv Ment Dis 179:259–265, 1991.

    PubMed  CAS  Google Scholar 

  91. Clark RE, Drake RE: Expenditures of time and money by families of people with severe mental illness and substance use disorder. Commun Ment Health J 30:193–206, 1994.

    Google Scholar 

  92. Dixon LB, McNary S, Lehman AF: Substance abuse and family relationships of persons with severe mental illness. Am J Psychiatry 152:456–458, 1995.

    PubMed  CAS  Google Scholar 

  93. Drake RE, Yovetich NA, Bebout RR, et al: Integrated treatment for dually diagnosed, homeless adults. JNervMent Dis 185:298–305, 1997.

    CAS  Google Scholar 

  94. Jerrell JM, Ridgely MS: Evaluating changes in symptoms and functioning of dually diagnosed clients in specialized treatment. Psychiatr Serv, 46:233–238, 1995.

    PubMed  CAS  Google Scholar 

  95. Drake RE, Osher FC, Wallach MA: Homelessness and dual diagnosis. Am Psychol 46:1149–1158,1991.

    Article  PubMed  CAS  Google Scholar 

  96. Benda BB, Datallo P: Homelessness: Consequence of a crisis or a long-term process? Hosp Commun Psychiatry 39:884–886, 1988.

    CAS  Google Scholar 

  97. Drake RE, Wallach MA, Teague GB, et al: Housing instability and homelessness among rural schizophrenic patients. Am J Psychiatry 148:330–336, 1991.

    PubMed  CAS  Google Scholar 

  98. Lamb HR, Lamb DM: Factors contributing to homelessness among the chronically and severely mentally ill. Hosp Commun Psychiatry 41:301–305, 1990.

    CAS  Google Scholar 

  99. Uehara ES: Race, gender, and housing inequality: An exploration of the correlates of low-quality housing among clients diagnosed with severe and persistent mental illness. J Health SocBehav 35:309–321, 1994.

    CAS  Google Scholar 

  100. Belcher JR: On becoming homeless: A study of chronically mentally ill persons. J Commun Psychol 17:173–185,1989.

    Google Scholar 

  101. Caton CL, Wyatt R, Felix A, et al: Follow-up of chronically homeless, mentally ill men. Am J Psychiatry 150:1639–1642, 1993.

    PubMed  CAS  Google Scholar 

  102. Dickey B, Gonzales O, Latimer E, et al: Use of mental health services by formerly homeless adults residing in group and independent housing. Psychiatr Serv 47:152–158, 1996.

    PubMed  CAS  Google Scholar 

  103. Hurlburt MS, Hough RL, Wood PA: Effects of substance abuse on housing stability of homeless mentally ill persons in supported housing. Psychiatr Serv 47:731–736, 1996.

    PubMed  CAS  Google Scholar 

  104. Bebout RR, Drake RE, Xie H, et al: Housing status among formerly homeless, dually diagnosed adults in Washington, DC. Psychiatr Serv 4936–941, 1997.

    Google Scholar 

  105. Shumway M, Chouljian CL, Hargreaves WA: Patterns of substance use in schizophrenia: A Markov modeling approach. J Psychiatr Res 28:277–287, 1994.

    Article  PubMed  CAS  Google Scholar 

  106. Chouljian TL, Shumway M, Balancio, et al: Substance use among schizophrenic outpatients: Prevalence, course, and relation to functional status. Ann Clin Psychiatry 7:19–24, 1995.

    Article  PubMed  CAS  Google Scholar 

  107. Dixon LB, Weiden PJ, Haas G, et al: Increased tardive dyskinesia in alcohol-abusing schizophrenic patients. Compr Psychiatry 33:121–122, 1992.

    Article  PubMed  CAS  Google Scholar 

  108. Carey MP, Weinhardt LS, Carey KB: Prevalence of infection with HIV among the seriously mentally ill: Review of the research and implications for practice. Prof Psychol Res Prac 26:262–268, 1995.

    Google Scholar 

  109. Cournois F, Empfield M, Honwath E, et al: HIV seroprevalence among patients admitted to two psychiatric hospitals. Am J Psychiatry 148:1225–1230, 1991.

    Google Scholar 

  110. Empfield M, Cournos F, Meyer I, et al: HIV seroprevalence among homeless patients admitted to a psychiatric inpatient unit. Am J Psychiatry 150:47–52, 1993.

    PubMed  CAS  Google Scholar 

  111. Meyer I, McKinnon K, Cournos F, et al: HIV seroprevalence among long-stay patients in a state psychiatric hospital. Hosp Commun Psychiatry 44:282–284, 1993.

    CAS  Google Scholar 

  112. Silberstein C, Galanter M, Marmor M, et al: HIV-1 among inner city dually diagnosed inpatients. Am J Drug Alcohol Abuse 20:101–113, 1994.

    PubMed  CAS  Google Scholar 

  113. Tracy JI, Josiassen RC, Bellack AS: Neuropsychology of dual diagnosis: Understanding the combined effects of schizophrenia and substance use disorder. Clin Psychol Rev 15:67–97, 1995.

    Google Scholar 

  114. Bowers MB, Mazure CM, Nelson JC, et al: Psychotogenic drug use and neuroleptic response. Schizophr Bull 16:81–85, 1990.

    PubMed  Google Scholar 

  115. Seibyl JP, Satel SL, Anthony D, et al: Effects of cocaine on hospital course in schizophrenia. J NervMentDis 181:31–37,1993.

    CAS  Google Scholar 

  116. Sokoloski KN, Cummings JL, Abrams BI, et al: Effects of substance abuse on hallucination rates and treatment responses in chronic psychiatric patients. J Clin Psychiatry 55:380–387, 1994.

    Google Scholar 

  117. Weiden PJ, Olfson M: Cost of relapse in schizophrenia. Schizophr Bull 21:419–429, 1995.

    PubMed  CAS  Google Scholar 

  118. Owen RR, Fischer EP, Booth BM, et al: Medication noncompliance and substance abuse among patients with schizophrenia. Psychiatr Sem 47:853–858, 1996.

    CAS  Google Scholar 

  119. Pristach CA, Smith CM: Medication compliance and substance abuse among schizophrenic patients. Hosp Commun Psychiatry 41:1345–1348, 1990.

    CAS  Google Scholar 

  120. Miller FT, Tanenbaum JH: Drug abuse in schizophrenia. Hosp Commun Psychiatry 40:847–849, 1989.

    CAS  Google Scholar 

  121. Zito JM, Routt WW, Mitchell JE, et al: Clinical characteristics of hospitalized psychotic patients who refuse antipsychotic drug therapy. Am J Psychiatry 142:822–826, 1989.

    Google Scholar 

  122. Cuffel BJ: Comorbid substance use disorder: Prevalence, patterns of use, and course, in Drake RE, Mueser KT (eds): Dual Diagnosis of Major Mental Illness and Substance Abuse, vol 2: Recent Research and Clinical Implications. San Francisco, Jossey-Bass, 1996, 93–105.

    Google Scholar 

  123. Dworkin RM: Patterns of sex differences in negative symptoms and social functioning consistent with separate dimensions of schizophrenic psychopathology. Am J Psychiatry 147:347–349, 1990.

    PubMed  CAS  Google Scholar 

  124. Szymanski S, Liebereman JA, Alvir JM, et al: Gender differences in onset of illness, treatment response, course, and biologic indexes in first episode schizophrenic patients. Am J Psychiatry 152:698–703, 1995.

    PubMed  CAS  Google Scholar 

  125. Drake RE, Brunette MF, Mueser KT: Substance use disorder and social functioning in schizophrenia, in Mueser KT, Tarrier N (eds): Handbook of Social Functioning in Schizophrenia. Boston, Allyn and Bacon, 1998, 280–289.

    Google Scholar 

  126. Noordsy DL, Drake RE, Biesanz JC, et al: Family history of alcoholism in schizophrenia. J Nerv MentDis 182:651–655,1994.

    CAS  Google Scholar 

  127. Wolford GL, Rosenberg SD, Oxman TE, et al: Evaluating current methods for detecting substance use disorder in persons with severe mental illness. submitted.

    Google Scholar 

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Drake, R.E., Brunette, M.F. (1998). Complications of Severe Mental Illness Related to Alcohol and Drug Use Disorders. In: Recent Developments in Alcoholism. Recent Developments in Alcoholism, vol 14. Springer, Boston, MA. https://doi.org/10.1007/0-306-47148-5_12

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