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Colorectal Cancer: Metastatic (Palliation)

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The ASCRS Textbook of Colon and Rectal Surgery

Abstract

Approximately 20% of patients with colorectal cancer present with established distant metastases. In most cases, the metastases are detectable with noninvasive imaging, and patients can be assigned to AJCC (American Joint Committee on Cancer) Stage IV before any surgical intervention. Among these patients there is enormous heterogeneity with respect to sites of disease, extent of disease, symptoms, performance status, and comorbidities. The clinical spectrum at the time of diagnosis ranges from the asymptomatic patient with a single metastatic lesion to the rapidly deteriorating patient with colon obstruction and advanced, multiorgan metastases. It is therefore difficult to define rigid treatment algorithms that can be widely applied to all clinical settings.

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D'Angelica, M., Idrees, K., Paty, P.B., Blumgart, L.H. (2007). Colorectal Cancer: Metastatic (Palliation). In: Wolff, B.G., et al. The ASCRS Textbook of Colon and Rectal Surgery. Springer, New York, NY. https://doi.org/10.1007/978-0-387-36374-5_34

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