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Detection of Malarial Parasites in Mosquitoes

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Advances in Disease Vector Research

Part of the book series: Advances in Disease Vector Research ((VECTOR,volume 8))

Abstract

Malaria is the most important parasitic disease in the tropics, with indigenous transmission in over 100 countries or areas of the world (122, 123). The World Health Organization (WHO) estimates the global incidence of this mosquito-transmitted disease to be approximately 100 million cases annually (67); other estimates are in the 200 to 400 million range (57, 101). In 1984, nearly 400 million people, one-twelfth of the world’s population, were living in areas where malaria is highly endemic and where no specific antimalarial measures were being applied. An additional 2700 million people, 56% of the world’s population, live in areas where malaria is still endemic but where control measures have reduced its level of endemicity. In many of these areas malaria is increasing dramatically (67, 122, 123).

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References

  1. Baker, E.Z., Beier, J.C., Meek, S.R., and Wirtz, R.A., 1987, Detection and quantitation of Plasmodium falciparum and Plasmodium vivax infections in Thai-Kampuchean Anopheles (Diptera: Culicidae) by enzyme-linked immunosorbent assay, J. Med. Entomol. 24:536–541.

    PubMed  CAS  Google Scholar 

  2. Beier, J.C., Asiago, C.M., Onyango, F.K., and Koros, J.K., 1988, ELISA absorbance cut-off method affects malaria sporozoite rate determination in wild Afrotropical Anopheles, Med. Vet. Entomol. 2:259–264.

    PubMed  CAS  Google Scholar 

  3. Beier, J.C., Onyango, F.K., Koros, J.K., Ramadhan, M., Ogwang, R., Koech, D.K., and Roberts, C.R., 1991, Quantitation of malaria sporozoites transmitted in vitro during salivation by wild Afrotropical Anopheles, Med. Vet. Entomol. 5:(in press).

    Google Scholar 

  4. Beier, J.C., Onyango, F.K., Ramadhan, M., Koros, J.K., Asiago, C.M., Koech, D.K., and Roberts, C.R., 1991, Quantitation of malaria sporozoites in the salivary glands of wild Afrotropical Anopheles, Med. Vet. Entomol. 5:(in press).

    Google Scholar 

  5. Beier, J.C., Perkins, P.V., Wirtz, R.A., Whitmire, R.E., Mugambi, M., and Hockmeyer, W.T., 1987, Field evaluation of an enzyme-linked immunosorbent assay (ELISA) for Plasmodium falciparum sporozoite detection in anopheline mosquitoes from Kenya, Am. J. Trop. Med. Hyg. 36:459–468.

    PubMed  CAS  Google Scholar 

  6. Beier, M.S., Schwartz, I.K., Beier, J.C., Perkins, P.V., Onyango, F., Koros, J.K., Campbell, G.H., Andrysiak, P.M., and Brandling-Bennett, A.D., 1988, Identification of malaria species by ELISA in sporozoite and oocyst infected Anopheles from western Kenya, Am. J. Trop. Med. Hyg. 39:323–327.

    PubMed  CAS  Google Scholar 

  7. Boudin, C., Robert, V., Verhave, J.P., Carnevale, P. and Meuweissen, J.H.E.T., 1988, La technique ELISA (enzyme-linked immuno-sorbent assay) dans la depistage des moustiques infectes par Plasmodium falciparum. I. Evaluation de la fiabilité et de l’efficacité du test. II. Application sur le terrain, Bull. W.H.O. 66:87–97.

    PubMed  CAS  Google Scholar 

  8. Boyd, M.F., 1949, Historical review. Boyd, M.F. (ed): in Malariology, vol. 1, W.B. Saunders Company, Philadelphia, pp. 3–25.

    Google Scholar 

  9. Bruce-Chwatt, L.J., 1985, Essential Malariology, William Heinemann Medical Books Ltd, London, 452 p.

    Google Scholar 

  10. Bruce-Chwatt, L.J., 1987, From Laveran’s discovery to DNA probes: New trends in diagnosis of malaria. Lancet 2:1509–1511.

    PubMed  CAS  Google Scholar 

  11. Bruce-Chwatt, L.J., 1988, History of malaria from prehistory to eradication. Wernsdorfer, W.H., and McGregor, I. (eds): in Malaria. Principles and Practice of Malariology, vol. 1, Churchill Livingstone, Edinburgh, pp. 1–59.

    Google Scholar 

  12. Burkot, T.R., 1988, Non-random host selection by anopheline mosquitoes, Parasitol. Today 4:156–162.

    PubMed  CAS  Google Scholar 

  13. Burkot, T.R., Dye, C., and Graves, P.M., 1989, An analysis of some factors affecting the sporozoite rates, human blood indexes and biting rates of the members of the Anopheles punctulatus complex in Papua New Guinea, Am. J. Trop. Med. Hyg. 40:229–234.

    PubMed  CAS  Google Scholar 

  14. Burkot, T.R., Graves, P.M., Cattani, J.A., Wirtz, R.A., and Gibson, F.D., 1987, The efficiency of sporozoite transmission in the human malaria, Plasmodium falciparum and P. vivax, Bull. W.H.O. 65:375–380.

    PubMed  CAS  Google Scholar 

  15. Burkot, T.R., Graves, P.M., Paru, R., Wirtz, R.A., and Heywood, P., 1988, Human malaria transmission studies in the Anopheles punctulatus complex in Papua New Guinea: Sporozoite rates, inoculation rates and sporozoite densities, Am. J. Trop. Med. Hyg. 39:135–144.

    PubMed  CAS  Google Scholar 

  16. Burkot, T.R., Graves, P.M., Wirtz, R.A., Brabin, B.J., Battistutta, D., Cattani, J.A., Maizels, R.M., and Alpers, M.P., 1989, Differential antibody responses to Plasmodium falciparum and Plasmodium vivax circumsporozoite proteins in a human population, J. Clin. Microbiol. 27:1346–1351.

    PubMed  CAS  Google Scholar 

  17. Burkot, T.R., Molineaux, L., Graves, P.M., Paru, R., Battistutta, D., Dagoro, H., Barnes, A., Wirtz, R.A., and Garner, P., 1990, The prevalence of naturally acquired multiple infections of Wuchereria bancrofti and human malarias in anophelines. Parasitology 100:369–375.

    PubMed  Google Scholar 

  18. Burkot, T.R., Williams, J.L., and Schneider, L., 1984, Identification of Plasmodium falciparum-infected mosquitoes by a double antibody enzyme-linked immunosorbent assay, Am. J. Trop. Med. Hyg. 33:783–788.

    PubMed  CAS  Google Scholar 

  19. Burkot, T.R., and Wirtz, R.A., 1986, Immunoassays of malaria sporozoites in mosquitoes, Parasitol. Today 2:155–157.

    PubMed  CAS  Google Scholar 

  20. Burkot, T.R., Wirtz, R.A., and Lyon, J., 1985, Use of fluorodinitrobenzene to identify monoclonal antibodies which are suitable for conjugation to periodate-oxidized horseradish peroxidase, J. Immunol Methods 84:25–31.

    PubMed  CAS  Google Scholar 

  21. Burkot, T.R., Zavala, F., Gwadz, R.W., Collins, F.H., Nussenzweig, R.S., and Roberts, D., 1984, Identification of malaria-infected mosquitoes by a two site enzyme linked immunosorbent assay, Am. J. Trop. Med. Hyg. 33: 227–231.

    PubMed  CAS  Google Scholar 

  22. Carter, R., and Graves, P.M., 1988, Gametocytes, Wernsdorfer, W.H., and McGregor, I. (eds): in Malaria. Principles and Practices in Malariology, vol. 1, Churchhill Livingstone, Edinburgh, pp. 253–306.

    Google Scholar 

  23. Carvajal, H., de Herrera, M.A., Quintero, J., Alzate, A., and Herrera, S., 1989, Anopheles neivai: A vector of malaria in the Pacific lowlands of Colombia, Trans. R. Soc. Trop. Med. Hyg. 83:609.

    PubMed  CAS  Google Scholar 

  24. Chen, D.H., Nussenzweig, R.S., Collins, W.E., 1976, Specificity of the circum-sporozoite precipitation antigen(s) of human and simian malarias, J. Parasitol. 62:636–637.

    PubMed  CAS  Google Scholar 

  25. Chulay, J.D., 1989, Development of sporozoite vaccines for malaria, Trans. R. Soc. Trop. Med. Hyg. (Suppl) 83:61–66.

    PubMed  Google Scholar 

  26. Coatney, G.R., Collins, W.E., Contacos, P.G., 1971, The Primate Malarias, U.S. Government Printing Office, District of Columbia, 336 p.

    Google Scholar 

  27. Cochrane, A.H., Collins, W.E., and Nussenzweig, R.S., 1984, Monoclonal antibody identifies circumsporozoite protein of Plasmodium malariae and detects a common epitope on Plasmodium brasilianum sporozoites, Infect. Immun. 45:592–595.

    PubMed  CAS  Google Scholar 

  28. Cochrane, A.H., Gwadz, R.W., Barnwell, J.W., Kamboj, K.K., and Nussenzweig, R.S., 1986, Further studies on the antigenic diversity of the circumsporozoite proteins of the Plasmodium cynomolgi complex, Am. J. Trop. Med. Hyg. 35:479–487.

    PubMed  CAS  Google Scholar 

  29. Cochrane, A.H., Ockenhouse, C.F., and Nussenzweig, R.S., 1984, Identification of circumsporozoite proteins in individual malaria-infected mosquitoes by Western blot analysis, J. Immunol. Methods 71:241–245.

    PubMed  CAS  Google Scholar 

  30. Cochrane, A.H., Uni, S., Maracic, M., di Giovanni, L., Aikawa, M., and Nussenzweig, R.S., 1989, A circumsporozoite-like protein is present in micronemes of mature blood stages of malaria parasites, Exp. Parasitol. 69: 351–356.

    PubMed  CAS  Google Scholar 

  31. Collins, F.H., Gwadz, R.W., Koontz, L.C., Zavala, F., and Nussenzweig, R.S., 1985, Laboratory assessment of a species-specific radioimmunoassay for the detection of malaria sporozoites in mosquitoes (Diptera: Culicidae), J. Med. Entomol. 22:121–129.

    PubMed  CAS  Google Scholar 

  32. Collins, F.H., Mendez, M.A., Rasmussen, P.C., Mehaffey, N.J., Besansky, N.J., and Finnerty, V., 1987, A ribosomal RNA gene probe differentiates member species of the Anopheles gambiae complex, Am. J. Trop. Med. Hyg. 37:37–41.

    PubMed  CAS  Google Scholar 

  33. Collins, F.H., Procell, P.M., Campbell, G.H., and Collins, W.E., 1988, Monoclonal antibody-based enzyme-linked immunosorbent assay (ELISA) for detection of Plasmodium malariae sporozoites in mosquitoes, Am. J. Trop. Med. Hyg. 38:283–288.

    PubMed  CAS  Google Scholar 

  34. Collins, F.H., Zavala, F., Graves, P.M., Cochrane, A.H., Gwadz, R.W., and Akoh, J., Nussenzweig, R.S., 1984, First field trial of an immunoradiometric assay for the detection of malaria sporozoites in mosquitoes, Am. J. Trop. Med. Hyg. 33:538–543.

    PubMed  CAS  Google Scholar 

  35. Coluzzi, M., 1988, Anopheline mosquitos: Genetic methods for species differentiation. Wernsdorfer, W.H., and McGregor, I. (eds): in Malaria. Principles and Practices in Malariology, vol. 1, Churchhill Livingstone, Edinburgh, pp. 411–430.

    Google Scholar 

  36. Corradetti, A., Verolini, R., Sebastiani, A., Proietti, A.M., and Amati, L., 1964, Fluorescent antibody testing with sporozoites of plasmodia, Bull. W.H.O. 30:747–751.

    PubMed  CAS  Google Scholar 

  37. Davis, J.R., Murphy, J.R., Clyde, D.F., Baqar, S., Cochrane, A.H., Zavala, F., and Nussenzweig, R.S., 1989, Estimate of Plasmodium falciparum sporozoite content of Anopheles stephensi used to challenge human volunteers, Am. J. Trop. Med. Hyg. 40:128–130.

    PubMed  CAS  Google Scholar 

  38. de Arruda, M., Carvalho, M.B., Nussenzweig, R.S., Maracic, M., Ferreira, A.W., and Cochrane, A.H., 1986, Potential vectors of malaria and their different susceptibility to Plasmodium falciparum and Plasmodium vivax in northern Brazil by immunoassay, Am. J. Trop. Med. Hyg. 35:873–881.

    PubMed  Google Scholar 

  39. de Arruda, M., Nardin, E.H., Nussenzweig, R.S., and Cochranc, A.H., 1989, Sero-epidemiological studies of malaria in indian tribes and monkeys of the Amazon basin of Brazil, Am. J. Trop. Med. Hyg. 41:379–385.

    PubMed  Google Scholar 

  40. Delves, C.J., Goman, M., Ridley, R.G., Matile, H., Lensen, T.H.W., Ponnudurai, T., and Scaife, J.G., 1989, Identification of Plasmodium falciparum-infected mosquitoes using a probe containing repetitive DNA, Mol. Biochem. Parasitol 32:105–112.

    PubMed  CAS  Google Scholar 

  41. Dye, C., 1986, Vectorial capacity: Must we measure all its components? Parasitol. Today 2:203–209.

    PubMed  CAS  Google Scholar 

  42. Esposito, F., Lombardi, S., Toure, Y.T., Zavala, F., and Coluzzi, M., 1986, Field observations on the use of antisporozoite monoclonal antibodies for determination of infection rates in malaria vectors, Parasitologia 28:30–37.

    Google Scholar 

  43. Ferreira, A., Enea, V., Morimoto, T., and Nussenzweig, V., 1986, Infectivity of Plasmodium burghei sporozoites measured with a DNA probe, Mol. Biochem. Parasitol. 19:103–109.

    PubMed  CAS  Google Scholar 

  44. Ferreira, A., Morimoto, T., Altszuler, R., and Nussenzweig, V., 1987, Use of a DNA probe to measure the neutralization of Plasmodium berghei sporozoites by a monoclonal antibody, J. Immunol. 138:1256–1259.

    PubMed  CAS  Google Scholar 

  45. Gabaldon, A., and Ulloa, G., 1978, A quick and easy method to determine the sporozoite index in mosquitoes, Trans. R. Soc. Trop. Med. Hyg. 72: 311–312.

    Google Scholar 

  46. Galinski, M.R., Arnot, D.E., Cochrane, A.H., Barnwell, J.W., Nussenzweig, R.S., and Enea, V., 1987, The circumsporozoite gene of the Plasmodium cynomolgi complex, Cell 48:311–319.

    PubMed  CAS  Google Scholar 

  47. Garnham, P.C.C., 1966, Malaria Parasites and Other Haemosporidia, Blackwell, Oxford, 1114 p.

    Google Scholar 

  48. Garnham, P.C.C., 1988, Malaria parasites of man: Life-cycles and morphology (excluding ultrastructure), Wernsdorfer, W.H., and McGregor, I. (eds): in Malaria. Principles and Practices in Malariology, vol. 1, Churchhill Livingstone, Edinburgh, pp. 61–96.

    Google Scholar 

  49. Garrett-Jones, C., 1964, Prognosis for interruption of malaria transmission through assessment of the mosquito’s vectorial capacity, Nature 204:1173–1175.

    PubMed  CAS  Google Scholar 

  50. Garrett-Jones, C., and Shidrawi, G.R., 1969, Malaria vectorial capacity of a population of Anopheles gambiae. An exercise in epidemiological entomology, Bull. W.H.O. 40:531–545.

    PubMed  CAS  Google Scholar 

  51. Gillies, M.T., 1988, Anopheline mosquitoes: Vector behavior and bionomics. Wernsdorfer, W.H. and McGregor, I. (eds): in Malaria. Principles and Practices in Malariology, vol. 1, Churchhill Livingstone, Edinburgh, pp. 453–485.

    Google Scholar 

  52. Golenda, C.F., Starkweather, W.H., and Wirtz, R.A., 1990, The distribution of circumsporozoite (CS) protein in Anopheles stephensi mosquitoes infected with Plasmodium falciparum malaria, J. Histochem. Cytochem. 38:475–481.

    PubMed  CAS  Google Scholar 

  53. Graves, P.M., Brabin, B.J., Charlwood, J.D., Burkot, T.R., Ginny, M., Paino, J., Cattani, J.A., Gibson, F.D., and Alpers, M.P., 1987, Reduction in incidence and prevalence of Plasmodium falciparum in under 5-year old children by permethrin impregnation of mosquito nets, Bull. W.H.O. 65: 869–877.

    PubMed  CAS  Google Scholar 

  54. Graves, P.M., Burkot, T.R., Saul, A. Hayes, R., and Carter, R., 1990, Estimation of anopheline survival rate, vectorial capacity, and mosquito infection probability from vector infection rates in villages near Madang, Papua New Guinea, J. Appl. Ecol. 27:134–147.

    Google Scholar 

  55. Greenwood, B.M., 1989, Impact of culture and environmental changes on epidemiology and control of malaria and babesiosis, Trans. R. Soc. Trop. Med. Hyg. (Suppl.) 83:25–29.

    PubMed  Google Scholar 

  56. Gunderson, J.H., Sogin, M.L., Wollett, G., Hollingdale, M., de la Cruz, V.F., Waters, A.P., and McCutchan, T.F., 1987, Structurally distinct, stagespecific ribosomes occur in Plasmodium, Science 238:933–937.

    PubMed  CAS  Google Scholar 

  57. Harwood, R.F., and James, M.T., 1979, Entomology in Human and Animal Health, New York, Macmillian, 548 p.

    Google Scholar 

  58. Hoedojo, Saleha, S., Makimian, R., Campbell, J., Franke, E., Santiyo, K., Gambiro, N. and Sustriayu, N., 1987, A preliminary study on detection of Plasmodium falciparum sporozoites in Anopheles aconitus, Mosquito-Borne Dis. Bull. 3:64–66.

    Google Scholar 

  59. Holmberg, M., and Wigzell, H., 1987, DNA hybridization assays for detection of malaria sporozoites in mosquitoes, Parasitol. Today 3:380.

    PubMed  CAS  Google Scholar 

  60. Ingram, R.L., Otken, L.B., and Jumper, R.J., 1961, Staining of malarial parasites by the fluorescent antibody technique, Proc. Soc. Exp. Biol. Med. 106:52–54.

    PubMed  CAS  Google Scholar 

  61. Johnson, A.M., and Baverstock, P.R., 1989, Rapid ribosomal RNA sequencing and the phylogenetic analysis of protists, Parasitol. Today 5: 102–105.

    PubMed  CAS  Google Scholar 

  62. Krotoski, W.A., Omar, M.S., and Jumper, J.R., 1974, Immunofluorescent staining of plasmodial oocysts in the mosquito, J. Parasitol. 60:344–347.

    PubMed  CAS  Google Scholar 

  63. Lanar, D.E., McLaughlin, G.L., Wirth, D.F., Barker, R.J., Zolg, J.W., and Chulay, J.D., 1989, Comparison of thick films, in vitro culture and DNA hybridization probes for detecting Plasmodium falciparum malaria, Am. J. Trop. Med. Hyg. 40:3–6.

    PubMed  CAS  Google Scholar 

  64. Lee, M., Harrison, B.A., and Lewis, G.E., 1990, A rapid sporozoite ELISA using 3,3′5,5′-tetramethylbenzidine as the substrate chromogen, Am. J. Trop. Med. Hyg. 42:314–319.

    PubMed  CAS  Google Scholar 

  65. Lindsay, S.W., Snow, R.W., Broomfield, G.L., Janneh, M.S., Wirtz, R.A., and Greenwood, B.M., 1989, Impact of permethrin-treated bednets on malaria transmission by the Anopheles gambiae complex in The Gambia, Med. Vet. Entomol. 3:263–271.

    PubMed  CAS  Google Scholar 

  66. Lombardi, S., Esposito, F., Zavala, F., Lamizana, L., Rossi, P., Sabatinelli, G., Nussenzweig, R.S., and Coluzzi, M., 1987, Detection and anatomical localization of Plasmodium falciparum circumsporozoite protein and sporozoites in the Afrotropical malaria vector Anopheles gambiae s.1, Am. J. Trop. Med. Hyg. 37:491–494.

    PubMed  CAS  Google Scholar 

  67. Malaria Action Programme, 1987, World malaria situation 1985, World Health Stat. Q. 40:142–170.

    Google Scholar 

  68. McCutchan, T.F., de al Cruz, V.F., Lal, A.A., Gunderson, J.H., Elwood, H.J., and Sogin, M.L., 1988, Primary sequences of two small subunit ribosomal RNA genes from Plasmodium falciparum, Mol. Biochem. Parasitol 28:63–68.

    PubMed  CAS  Google Scholar 

  69. McLaughlin, G.L., Ruth, J.L., Jablonski, E., Steketee, R., and Campbell, G.H., 1987, Use of enzyme-linked synthetic DNA in diagnosis of falciparum malaria, Lancet 1(8535):714–716.

    PubMed  CAS  Google Scholar 

  70. Molineaux, L., and Gramiccia, G. 1980. The Garki Project. Research on the Epidemiology and Control of Malaria in the Sudan Savanna of West Africa, World Health Organization, Genera, 311 p.

    Google Scholar 

  71. Molineaux, L., Muir, D.A., Spencer, H.C., and Wernsdorfer, W.H., 1988, The Epidemiology of Malaria and Its Measurements. Wernsdorfer, W.H., and McGregor, I. (eds): in Malaria. Principles and Practices of Malariology, vol. 2, Churchhill Livingstone, Edinburgh, pp. 999–1089.

    Google Scholar 

  72. Muir, D.A., 1988, Anopheline mosquitoes: Vector reproduction, life-cycle and biotype, Wernsdorfer, W.H., and McGregor, I. (eds): in Malaria. Principles and Practices in Malariology, vol. 1, Churchhill Livingstone, Edinburgh, pp. 431–451.

    Google Scholar 

  73. Nardin, E., Gwadz, R.W., and Nussenzweig, R.S., 1979, Characterization of sporozoite surface antigens by indirect immunofluorescence: Detection of stage-and species-specific antimalarial antibodies, Bull. W.H.O. 57(Suppl. 1):211–217.

    PubMed  Google Scholar 

  74. Nardin, E.H., and Nussenzweig, R.S., 1978, Stage-specific antigens on the surface membrane of sporozoites of malaria parasites, Nature 274:55–57.

    PubMed  CAS  Google Scholar 

  75. Nardin, E.H., Nussenzweig, R.S., Nussenzweig, V., Harinasuta, K.T., Collins, W.E., Tapschaisri, P., and Chomcharn, Y., 1982, Circumsporozoite (CS) proteins of human malaria parasites Plasmodium falciparum and Plasmodium vivax, J. Exp. Med. 156:20–30.

    PubMed  CAS  Google Scholar 

  76. Nussenzweig, R.S., Montuori, W., Spitalny, and Chen, D., 1973, Antibodies against sporozoites of human and simian malaria produced in rats, J. Immunol. 110:600–601.

    PubMed  CAS  Google Scholar 

  77. Nussenzweig, V., and Nussenzweig, R.S., 1986, Development of a sporozoite malaria vaccine, Am. J. Trop. Med. Hyg. 35:678–688.

    PubMed  CAS  Google Scholar 

  78. Peters, W., 1960, Studies on the epidemiology of malaria in New Guinea, Trans. Roy. Soc. Trop. Med. Hyg. 54:242–251.

    PubMed  CAS  Google Scholar 

  79. Petros, B.L., Procell, P.M., Campbell, G.H., and Collins, F.H., 1989, A nitrocellulose membrane-based ELISA for the detection of Plasmodium infections in mosquitoes, Bull. W.H.O. 67:525–533.

    PubMed  CAS  Google Scholar 

  80. Ponnudurai, T., Lensen, A.H.W., van Gemert, G.J.A., Bensink, M.P.E., Bolmer, M., and Meuwissen, J.H.E.Th., 1989, Sporozoite load of mosquitoes infected with Plasmodium falciparum, Trans. Roy. Soc. Trop. Med. Hyg. 83:67–70.

    PubMed  CAS  Google Scholar 

  81. Post, R.J., and Crampton, J.M., 1987, Probing the unknown, Parasitol. Today 3:380–383.

    PubMed  CAS  Google Scholar 

  82. Pringle, G., 1965, A count of the sporozoites in an oocyst of Plasmodium falciparum, Trans. R. Soc. Trop. Med. Hyg. 59:289–290.

    PubMed  CAS  Google Scholar 

  83. Pringle, G., 1966, A quantitative study of naturally acquired malaria infections in Anopheles gambiae and Anopheles funestus in a highly malarious area of East Africa, Trans. R. Soc. Trop. Med. Hyg. 60:626–632.

    PubMed  CAS  Google Scholar 

  84. Procell, P.M., Collins, W.E., and Campbell, G.H., 1988, Circumsporozoite protein of the human malaria parasite Plasmodium ovale identified with monoclonal antibodies, Infect. Immun. 56:376–379.

    PubMed  CAS  Google Scholar 

  85. Ramsey, J.M., Beaudoin, R.L., Bawden, M.P., and Espinal, C.A., 1981, Taxonomic identification of malaria sporozoites by indirect fluorescent antibody assay, WHO/MAL81.971, 1 p.

    Google Scholar 

  86. Ramsey, J.M., Beaudoin, R.L., Bawden, M.P., and Espinal, C.A., 1983, Specific identification of Plasmodium sporozoites using an indirect fluorescent antibody method, Trans. Roy. Soc. Trop. Med. Hyg. 77:378–381.

    PubMed  CAS  Google Scholar 

  87. Ramsey, J.M., Bown, D.N., Aron, J.L., Beaudoin, R.L., and Mendez, J.F., 1986, Field trail in Chiapas, Mexico, of a rapid detection method for malaria in anopheline vectors with low infection rates, Am. J. Trop. Med. Hyg. 35:234–238.

    PubMed  CAS  Google Scholar 

  88. Reid, J.A., 1968, Anopheline Mosquitoes of Malaya and Borneo, Government of Malaysia, Kuala Lumpur, 520 p.

    Google Scholar 

  89. Robert, V., Verhave, J.P., Ponnudurai, T., Louwe, L., Scholtens, P., and Carnevale, P., 1988, Study of the distribution of circumsporozoite antigen in Anopheles gambiae infected with Plasmodium falciparum, using the enzymelinked immunosorbent assay, Trans. R. Soc. Trop. Med. Hyg. 82: 289–391.

    Google Scholar 

  90. Rosenberg, R., 1985, Inability of Plasmodium knowlesi sporozoites to invade Anopheles freeborni salivary glands, Am. J. Trop. Med. Hyg. 34:687–691.

    PubMed  CAS  Google Scholar 

  91. Rosenberg, R., Andre, R.G., and Somchit, L., 1990, Highly efficient dry season transmission of malaria in Thailand, Trans. R. Soc. Trop. Med. Hyg. 84:22–28.

    PubMed  CAS  Google Scholar 

  92. Rosenberg, R., Wirtz, R.A., Lanar, D.E., Sattabongkot, J., Hall, T., Waters, A.P., and Prasittisuk, C., 1989, Circumsporozoite protein heterogeneity in the human malaria parasite Plasmodium vivax, Science 245:973–976.

    PubMed  CAS  Google Scholar 

  93. Rosenberg, R., Wirtz, R.A., Schneider, I., and Burge, R., 1990, An estimation of the number of malaria sporozoites ejected by a feeding mosquito, Trans. R. Soc. Trop. Med. Hyg. 84:209–212.

    PubMed  CAS  Google Scholar 

  94. Russell, P.F., West, L.S., Manwell, R.D., and MacDonald, G., 1963, Practical Malariology, Oxford University Press, London, 2nd ed., 750 p.

    Google Scholar 

  95. Saul, A., Graves, P.M., and Kay, B.H., 1990, A cyclical model of disease transmission and its application to determining vectorial capacity from vector infection rates. J. Appl. Ecol. 27:123–133.

    Google Scholar 

  96. Service, M., 1976, Mosquito Ecology: Field sampling methods. Applied Science Publishers, London, 583 p.

    Google Scholar 

  97. Shute, P.G., and Maryon, M., 1952, A study of human oocysts as an aid to species diagnosis, Trans. R. Soc. Trop. Med. Hyg. 46:275–292.

    PubMed  CAS  Google Scholar 

  98. Sinden, R.E., 1984, The biology of Plasmodium in the mosquito, Experientia 40:1330–1343.

    PubMed  CAS  Google Scholar 

  99. Sodeman, W.A., Jr., and Jeffery, G.M., 1964, Immunofluorescent staining of sporozoites of Plasmodium gallinaceum, J. Parasitol. 50:477–478.

    Google Scholar 

  100. Sodeman, W.A., Jr., Jeffery, G.M., and Collins, W.E., 1964, Fluorescent antibody studies in experimental malarias. I. Studies on Plasmodium gallinaceum and Plasmodium berghei, Proc. First Int. Congr. Parasit. 1: 224–230.

    Google Scholar 

  101. Sturchler, D., 1989, How much malaria is there worldwide? Parasitol. Today 5:39–40; ibid. 5:384.

    Google Scholar 

  102. Subbarao, S.K., Adak, T., Vasantha, K., Joshi, H., Raghvendra, K., Cochrane, A.H., Nussenzweig, R.A., and Sharma, V.P., 1988. Susceptibility of Anopheles culicifacies species A and B to Plasmodium vivax and Plasmodium falciparum as determined by immunoradiometic assay, Trans. R. Soc. Trop. Med. Hyg. 82:394–397.

    PubMed  CAS  Google Scholar 

  103. Tang, V.C.W., Hancock, K., and Maddison, S.E., 1984, Quantitative capacities of glutaraldehyde and sodium m-periodate coupled peroxidaseanti-human IgG conjugates in enzyme-linked immunoassays, J. Immunol. Methods 70:91–100.

    Google Scholar 

  104. Vanderberg, J.P., and Gwadz, R.W., 1980, The transmission by mosquitoes of plasmodia in the laboratory, Kreier, J.P. (ed): in Malaria, vol. 2, Academic, New York, pp. 154–234.

    Google Scholar 

  105. Vanderberg, J.P., Nussenzweig, R., and Most, H. 1969. Protective immunity produced by the injection of X-irradiated sporozoites of Plasmodium berghei. V. In vitro effects of immune serum on sporozoites, Milit. Med. (Suppl.) 134:1183–1190.

    CAS  Google Scholar 

  106. Verhave, J.P., Leewenberg, A.D.E.M., Ponnudurai, T., Meuwissen, J.H.E.Th., and van Druten, J.A.M., 1988, The biotin-streptavidin system in a two-site ELISA for the detection of plasmodial sporozoite antigen in mosquitoes, Parasite Immunol. 10:17–31.

    PubMed  CAS  Google Scholar 

  107. Viriyakosol, S., Snounou, G., and Brown, K.N., 1989, The use of a DNA probe for the differentiation of rodent malaria strains and species, Mol. Biochem. Parasitol. 32:93–100.

    PubMed  CAS  Google Scholar 

  108. Ward, R.A., 1962, Preservation of mosquitoes for malarial oocyst and sporozoite dissections, Mosquito News 22:306–307.

    Google Scholar 

  109. Warren, M., Mason, J., and Hobbs, J., 1975, Natural infections of Anopheles albimanus with Plasmodium in a small malaria focus, Am. J. Trop. Med. Hyg. 24: 545–546.

    PubMed  CAS  Google Scholar 

  110. Waters, A.P., and McCutchan, T., 1989, Rapid, sensitive diagnosis of malaria based on ribosomal RNA, Lancet 17 June 8651:1343–1346.

    Google Scholar 

  111. Weber, J.L., and Hockmeyer, W.T., 1985, Structure of the circumsporozoite proteins in 18 strains of Plasmodium falciparum, Mol. Biochem. Parasitol. 15:305–316.

    PubMed  CAS  Google Scholar 

  112. Wernsdorfer, W.H. 1980. The importance of malaria in the world. Kreier, J.P., (ed): in Malaria, vol. 1, Academic, New York, pp. 1–93.

    Google Scholar 

  113. Wharton, R.H., Eyles, D.E., Warren, M., Moorhouse, D.E., and Sandosham, A.A., 1963, Investigations leading to the identification of members of the Anopheles umbrosus group as the probable vectors of mouse deer malaria, Bull. W.H.O. 29:357–374.

    PubMed  CAS  Google Scholar 

  114. White, G.B., 1989, Malaria, in Geographical Distribution of Arthropodborne Diseases and their Principal Vectors (WHO/VBC/89.967). 1:7–22. World Health Organization/Division of Vector Biology and Control, Geneva 134 p.

    Google Scholar 

  115. Wilkinson, R.N., 1980, Detection of malarial sporozoites by the enzyme linked immunosorbent assay (ELISA), PhD Dissertation, University of Texas Health Science Center at Houston, Texas. 80 p.

    Google Scholar 

  116. Wirtz, R.A., Burkot, T.R., Andre, R.G., Rosenberg, R., Collins, W.E., and Roberts, D.R., 1985, Identification of Plasmodium vivax sporozoites in mosquitoes using an enzyme-linked immunosorbent assay, Am. J. Trop. Med. Hyg. 34:1048–1054.

    PubMed  CAS  Google Scholar 

  117. Wirtz, R.A., Burkot, T.R., Graves, P.M., and Andre, R.G., 1987, Field evaluation of enzyme-linked immunosorbent assays (ELISAs) for Plasmodium falciparum and Plasmodium vivax sporozoites in mosquitoes (Diptera: Culicidae) from Papua New Guinea, J. Med. Entomol. 24:433–437.

    PubMed  CAS  Google Scholar 

  118. Wirtz, R.A., Charoenvit, Y., Burkot, T.R., Esser, K.M., Beaudoin, R.L., Collins, W.E., and Andre, R.G., 1991, Evaluation of monoclonal antibodies against Plasmodium vivax sporozoites for ELISA development. Med. Vet. Entomol. 5:(in press).

    Google Scholar 

  119. Wirtz, R.A., Zavala, F., Charoenvit, Y., Campbell, G.H., Burkot, T.R., Schneider, I., Esser, K.M., Beaudoin, R.L., and Andre, R.G., 1987, Comparative testing of monoclonal antibodies against Plasmodium falciparum sporozoites for ELISA development, Bull. W.H.O. 65:39–45.

    PubMed  CAS  Google Scholar 

  120. World Health Organization, 1975, Manual on Practical Entomology in Malaria. World Health Organization, Geneva, 191 p.

    Google Scholar 

  121. World Health Organization, 1986, The use of DNA probes for malaria diagnosis: Memorandum from a WHO meeting, Bull. W.H.O. 64:641–652.

    Google Scholar 

  122. World Health Organization, 1987, Tropical Disease Research: A global Partnership, Geneva, WHO, 191 p.

    Google Scholar 

  123. World Health Organization, 1988, Tropical Disease Research: Science at Work, Geneva, WHO, 64 p.

    Google Scholar 

  124. Zavala, F. Cochrane, A.H., Nardin, E.H., Nussenzweig, R.S., and Nussenzweig, V., 1983, Circumsporozoite proteins of malaria parasites contain a single immunodominant region with two or more identical epitopes, J. Exp. Med. 157:1947–1957.

    PubMed  CAS  Google Scholar 

  125. Zavala, F., Gwadz, R.W., Collins, F.H., Nussenzweig, R.S. and Nussenzweig, V., 1982, Monoclonal antibodies to circumsporozoite proteins identify the species of malaria parasite in infected mosquitoes, Nature 299:737–738.

    PubMed  CAS  Google Scholar 

  126. Zavala, F., Musuda, A., Graves, P.M., Nussenzweig, V., and Nussenzweig, R.S., 1985, Ubiquity of the repetitive epitope of the CS protein in different isolates of human malaria parasites, J. Immunol. 135:2790–2793.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Entomology, Walter Reed Army Institute of Research, Washington D.C., 20307-5100, USA

    Robert A. Wirtz

  2. Tropical Health Program, Queensland Institute of Medical Research, Bramston Terrace, Herston, Brisbane, Queensland, 4006, Australia

    Thomas R. Burkot

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  1. Robert A. Wirtz
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  1. Virus Vector Laboratory, Department of Entomology, Texas A&M University, College Station, TX, 77843, USA

    Kerry F. Harris

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Wirtz, R.A., Burkot, T.R. (1991). Detection of Malarial Parasites in Mosquitoes. In: Harris, K.F. (eds) Advances in Disease Vector Research. Advances in Disease Vector Research, vol 8. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3110-3_4

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