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Choroidal and Retinal Metastasis

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Retinal and Choroidal Manifestations of Selected Systemic Diseases

Abstract

Metastasis to the eye involves the choroid (88%), iris (9%), or ciliary body (2%), and rarely the retina (<1%). Intraocular metastases most commonly originate from primary cancers in the breast (47%), lung (21%), gastrointestinal tract (4%), kidney (2%), skin (melanoma) (2%), prostate gland (2%), and other sites (4%). Metastases are unilateral in 76% of cases and bilateral in 24%. Patient prognosis is poor, and those with metastatic skin melanoma or lung carcinoma typically show survival less than 1 year. Those with metastases from breast cancer show survival of 65% at 1 year, 34% at 3 years, and 24% at 5 years.

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Authors and Affiliations

  1. Wills Eye Institute, Thomas Jefferson University Hospital, 840 Walnut Street, Suite 1440, Philadelphia, PA, 19107, USA

    Carol L. Shields M.D. & Jerry A. Shields M.D.

Authors
  1. Carol L. Shields M.D.
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  2. Jerry A. Shields M.D.
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Correspondence to Carol L. Shields M.D. .

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Editors and Affiliations

  1. Johns Hopkins University, School of Medicine, The Retina Division,Wilmer Eye Institute, Al-Oruba Street, PO Box 7191, Riyadh, 1010, Saudi Arabia

    J. Fernando Arévalo

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Shields, C.L., Shields, J.A. (2013). Choroidal and Retinal Metastasis. In: Arévalo, J. (eds) Retinal and Choroidal Manifestations of Selected Systemic Diseases. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3646-1_14

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  • DOI: https://doi.org/10.1007/978-1-4614-3646-1_14

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