Abstract
Transgenic animals, in which the transgene has been engineered to mimic mutations known to cause photoreceptor degenerations in humans, provide powerful models of the diseases known as retinitis pigmentosa. Here we describe the time course of photoreceptor death in rats in which degeneration is caused by a rhodopsin transgene containing the P23H or S334ter mutations.
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Lee, D. et al. (2003). Photoreceptor Degeneration in Pro23His and S334ter Transgenic Rats. In: LaVail, M.M., Hollyfield, J.G., Anderson, R.E. (eds) Retinal Degenerations. Advances in Experimental Medicine and Biology, vol 533. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0067-4_36
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DOI: https://doi.org/10.1007/978-1-4615-0067-4_36
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