Abstract
The evidence of primary extranodal marginal zone B-cell lymphoma of the efferent tear ducts1-3 indicates the presence of pre-existent organized lymphoid tissue at that site. This is a low-grade B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) type. The mucosa of the lacrimal sac and the nasolacrimal duct consists of a double-layered epithelium with scattered lymphocytes or groups of lymphocytes. Although the mucosa of the efferent tear ducts plays an important role in defense against foreign antigens and various types of microbial pathogens, organized MALT may or may not be a normal component of the human efferent lacrimal system.4 In the present study, human lacrimal sac and nasolacrimal ducts were examined for lymphoid tissue with the structure and immunophenotype of organized MALT.
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© 2002 Kluwer Academic/Plenum Publishers
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Paulsen, F.P., Paulsen, J.I., Thale, A.B., Schaudig, U., Tillmann, B.N. (2002). Organized Mucosa-Associated Lymphoid Tissue in Human Nasolacrimal Ducts. In: Sullivan, D.A., Stern, M.E., Tsubota, K., Dartt, D.A., Sullivan, R.M., Bromberg, B.B. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3. Advances in Experimental Medicine and Biology, vol 506. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0717-8_123
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DOI: https://doi.org/10.1007/978-1-4615-0717-8_123
Publisher Name: Springer, Boston, MA
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