Abstract
As an extension of IVF techniques, preimplantation genetic diagnosis will make it possible to detect genetic and chromosomal diseases in embryos. With the use of molecular genetic technology, such as Polymerase Chain Reaction (PCR), several gene mutations have already been detected in polar bodies aspirated from mature oocytes or in blastomeres from biopsied embryos (Verlinsky, this volume). The same approach was used for gender determination in cases at high risk of X-linked diseases to avoid the birth of affected males (Handyside, this volume; Milayeva, this volume).
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© 1991 Plenum Press, New York
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Plachot, M. (1991). Chromosome Analysis of Oocytes and Embryos. In: Verlinsky, Y., Kuliev, A. (eds) Preimplantation Genetics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1351-9_11
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DOI: https://doi.org/10.1007/978-1-4684-1351-9_11
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