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Classification and Evolution of Human Rhinoviruses

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Rhinoviruses

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1221))

Abstract

The historical classification of human rhinoviruses (RV) by serotyping has been replaced by a logical system of comparative sequencing. Given that strains must diverge within their capsid sequenced by a reasonable degree (>12–13 % pairwise base identities) before becoming immunologically distinct, the new nomenclature system makes allowances for the addition of new, future types, without compromising historical designations. Currently, three species, the RV-A, RV-B, and RV-C, are recognized. Of these, the RV-C, discovered in 2006, are the most unusual in terms of capsid structure, receptor use, and association with severe disease in children.

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Acknowledgements

This work was supported by NIH grant U19 AI104317. The authors thank Wolters Kluwer, publishers of Field’s Virology (2013), for permission to include certain text and figures from Ch 18, “Rhinoviruses” by the same authors.

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Authors and Affiliations

  1. Institute for Molecular Virology, University of Wisconsin-Madison, 1525 Linden Drive, Madison, WI, 53706, USA

    Ann C. Palmenberg

  2. Department of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA

    James E. Gern

Authors
  1. Ann C. Palmenberg
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  2. James E. Gern
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Corresponding author

Correspondence to Ann C. Palmenberg .

Editor information

Editors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Faculty of Health, Nursing and Medical Sciences,, Monash University, Melbourne, Victoria, Australia

    David A. Jans

  2. Centre for Research in Therapeutic Solutions, Faculty of Education, Science, Technology and Mathematics, University of Canberra, Canberra, Aust Capital Terr, Australia

    Reena Ghildyal

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Palmenberg, A.C., Gern, J.E. (2015). Classification and Evolution of Human Rhinoviruses. In: Jans, D., Ghildyal, R. (eds) Rhinoviruses. Methods in Molecular Biology, vol 1221. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1571-2_1

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  • DOI: https://doi.org/10.1007/978-1-4939-1571-2_1

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-1570-5

  • Online ISBN: 978-1-4939-1571-2

  • eBook Packages: Springer Protocols

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