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Human Mesenchymal Stem Cells: Basic Biology and Clinical Applications for Bone Tissue Regeneration

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Trends in Stem Cell Biology and Technology

Abstract

Mesenchymal stem cells (MSCs) are a group of clonogenic cells present among the bone marrow stroma and capable of multilineage differentiation into mesoderm-type cells such as osteoblasts, adipocytes, and chondrocytes. Because of their ease of isolation and this wide differentiation potential, MSCs are being introduced into clinical medicine in a variety of applications. Here we discuss the characteristics of MSCs, their differentiation, as well as the challenges faced when they are used in cell therapy for bone regeneration.

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  1. Endocrinology Research Laboratory (KMEB), Department of Endocrinology, Odense University Hospital, Kloevervaenget 6, 4th floor, DK-5000, Odense, Denmark

    Basem M. Abdallah, Hamid Saeed & Moustapha Kassem

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  1. Basem M. Abdallah
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Correspondence to Moustapha Kassem .

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    Abdallah, B.M., Saeed, H., Kassem, M. (2009). Human Mesenchymal Stem Cells: Basic Biology and Clinical Applications for Bone Tissue Regeneration. In: Baharvand, H. (eds) Trends in Stem Cell Biology and Technology. Humana Press. https://doi.org/10.1007/978-1-60327-905-5_12

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