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Visual Evoked Potential Recording in Rodents

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Stimulation and Inhibition of Neurons

Part of the book series: Neuromethods ((NM,volume 78))

Abstract

The visual evoked potential (VEP) is an electronic potential recorded from the visual cortex in response to a visual stimulus. It provides a means to examine the function of the visual pathway from the retina to the occipital cortex. The most common animals employed in VEP laboratory studies are rats. In this chapter, we describe the basic ‘flash VEP’ recording protocol in rodents and discuss the practical aspects of the preparation including anaesthesia methods, electrode configuration, stimulus design, dark adaptation, filter settings and signal sampling with the authors’ personal experience. We also review the recent use of the VEP in laboratory researches in several optic nerve disease models, including glaucoma, ischemic optic neuropathy and optic neuritis.

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Author information

Authors and Affiliations

  1. Australian School of Advanced Medicine, Macquarie University, North Ryde, NSW, Australia

    Yuyi You, Alexander Klistorner & Stuart L. Graham

  2. Save Sight Institute, University of Sydney, Sydney, NSW, Australia

    Alexander Klistorner & Stuart L. Graham

Authors
  1. Yuyi You
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  2. Alexander Klistorner
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  3. Stuart L. Graham
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Corresponding author

Correspondence to Stuart L. Graham .

Editor information

Editors and Affiliations

  1. , Australian School of Advanced Medicine, Macquarie University, Technology Place 2, North Ryde, 2113, New South Wales, Australia

    Paul M. Pilowsky

  2. , Australian School of Advanced Medicine, Macquarie University, Technology Place 2, North Ryde, 2113, New South Wales, Australia

    Melissa M.J. Farnham

  3. , Australian School of Advanced Medicine, Macquarie University, Technology Place 2, North Ryde, 2113, New South Wales, Australia

    Angelina Y. Fong

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You, Y., Klistorner, A., Graham, S.L. (2013). Visual Evoked Potential Recording in Rodents. In: Pilowsky, P., Farnham, M., Fong, A. (eds) Stimulation and Inhibition of Neurons. Neuromethods, vol 78. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-233-9_16

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  • DOI: https://doi.org/10.1007/978-1-62703-233-9_16

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-232-2

  • Online ISBN: 978-1-62703-233-9

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