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Venous Disease

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Cardiovascular Medicine

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References

  1. Goldhaber SZ. Pulmonary embolism. Lancet 2004;363:1295–1305.

    Article  PubMed  Google Scholar 

  2. Stein PD, Hull RD, Kayali F, Ghali WA, Alshab AK, Olson RE. Venous thromboembolism according to age: the impact of an aging population. Arch Intern Med 2004;164:2260–2265.

    Article  PubMed  Google Scholar 

  3. White RH. The epidemiology of venous thromboembolism. Circulation 2003;107:I4–I8.

    Article  PubMed  Google Scholar 

  4. Goldhaber SZ, Morrison RB. Cardiology patient pages. Pulmonary embolism and deep vein thrombosis. Circulation 2002;106:1436–1438.

    Article  PubMed  Google Scholar 

  5. Goldhaber SZ, Grasso-Correnti N. Cardiology patient pages. Treatment of blood clots. Circulation 2002;106:e138–e140.

    Article  PubMed  Google Scholar 

  6. Goldhaber SZ, Fanikos J. Prevention of deep vein thrombosis and pulmonary embolism. Circulation 2004;110:e445–e447.

    Article  PubMed  Google Scholar 

  7. Goldhaber SZ, Dunn K, MacDougall RC. New onset of venous thromboembolism among hospitalized patients at Brigham and Women’s Hospital is caused more often by prophylaxis failure than by withholding treatment. Chest 2000;118:1680–1684.

    Article  PubMed  CAS  Google Scholar 

  8. Goldhaber SZ, Turpie AG. Prevention of venous thromboembolism among hospitalized medical patients. Circulation 2005;111:e1–e3.

    Article  PubMed  Google Scholar 

  9. Oger E. Incidence of venous thromboembolism: a communitybased study in Western France. EPI-GETBP Study Group. Groupe d’Etude de la Thrombose de Bretagne Occidentale. Thromb Haemost 2000;83:657–660.

    PubMed  CAS  Google Scholar 

  10. Cushman M, Tsai AW, White RH, et al. Deep vein thrombosis and pulmonary embolism in two cohorts: the longitudinal investigation of thromboembolism etiology. Am J Med 2004;117:19–25.

    Article  PubMed  Google Scholar 

  11. Goldhaber SZ, Tapson VF. A prospective registry of 5,451 patients with ultrasound-confirmed deep vein thrombosis. Am J Cardiol 2004;93:259–262.

    Article  PubMed  Google Scholar 

  12. Anderson FA Jr, Spencer FA. Risk factors for venous thromboembolism. Circulation 2003;107:I9–I16.

    Article  PubMed  Google Scholar 

  13. Meignan M, Rosso J, Gauthier H, et al. Systematic lung scans reveal a high frequency of silent pulmonary embolism in patients with proximal deep venous thrombosis. Arch Intern Med 2000;160:159–164.

    Article  PubMed  CAS  Google Scholar 

  14. Kucher N, Tapson VF, Goldhaber SZ, Committee for the DVT Free Steering Committee. Risk factors associated with symptomatic pulmonary embolism in a large cohort of DVT patients. Thromb Haemost 2005;93:494–498.

    PubMed  CAS  Google Scholar 

  15. Vaitkus PT, Leizorovicz A, Cohen AT, Turpie AG, Olsson CG, Goldhaber SZ. Mortality rates and risk factors for asymptomatic deep vein thrombosis in medical patients. Thromb Haemost 2005;93:76–79.

    PubMed  CAS  Google Scholar 

  16. Prandoni P, Lensing AW, Cogo A, et al. The long-term clinical course of acute deep venous thrombosis. Ann Intern Med 1996;125:1–7.

    PubMed  CAS  Google Scholar 

  17. Heit JA, Mohr DN, Silverstein MD, Petterson TM, O’Fallon WM, Melton LJ 3rd. Predictors of recurrence after deep vein thrombosis and pulmonary embolism: a population-based cohort study. Arch Intern Med 2000;160:761–768.

    Article  PubMed  CAS  Google Scholar 

  18. Prandoni P, Bilora F, Marchiori A, et al. An association between atherosclerosis and venous thrombosis. N Engl J Med 2003;348:1435–1441.

    Article  PubMed  Google Scholar 

  19. Sobieszczyk P, Fishbein MC, Goldhaber SZ. Acute pulmonary embolism: don’t ignore the platelet. Circulation 2002;106:1748–1749.

    Article  PubMed  Google Scholar 

  20. Nicolaides AN. Investigation of chronic venous insufficiency: a consensus statement. Circulation 2000;102:e126–e163.

    PubMed  CAS  Google Scholar 

  21. Joffe HV, Kucher N, Tapson VF, Goldhaber SZ. Upper-extremity deep vein thrombosis: a prospective registry of 592 patients. Circulation 2004;110:1605–1611.

    Article  PubMed  Google Scholar 

  22. Wells PS, Anderson DR, Bormanis J, et al. Value of assessment of pretest probability of deep-vein thrombosis in clinical management. Lancet 1997;350:1795–1798.

    Article  PubMed  CAS  Google Scholar 

  23. Kearon C, Ginsberg JS, Douketis J, et al. Management of suspected deep venous thrombosis in outpatients by using clinical assessment and D-dimer testing. Ann Intern Med 2001;135:108–111.

    PubMed  CAS  Google Scholar 

  24. Wells PS, Anderson DR, Rodger M, et al. Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis. N Engl J Med 2003;349:1227–1235.

    Article  PubMed  CAS  Google Scholar 

  25. Zierler BK. Ultrasonography and diagnosis of venous thromboembolism. Circulation 2004;109:I9–I14.

    Article  PubMed  Google Scholar 

  26. Stevens SM, Elliott CG, Chan KJ, Egger MJ, Ahmed KM. Withholding anticoagulation after a negative result on duplex ultrasonography for suspected symptomatic deep venous thrombosis. Ann Intern Med 2004;140:985–991.

    PubMed  Google Scholar 

  27. Ginsberg JS, Wells PS, Hirsh J, et al. Reevaluation of the sensitivity of impedance plethysmography for the detection of proximal deep vein thrombosis. Arch Intern Med 1994;154:1930–1933.

    Article  PubMed  CAS  Google Scholar 

  28. Loud PA, Katz DS, Belfi L, Grossman ZD. Imaging of deep venous thrombosis in suspected pulmonary embolism. Semin Roentgenol 2005;1:33–40.

    Article  Google Scholar 

  29. Fraser DG, Moody AR, Morgan PS, Martel AL, Davidson I. Diagnosis of lower-limb deep venous thrombosis: a prospective blinded study of magnetic resonance direct thrombus imaging. Ann Intern Med 2002;136:89–98.

    PubMed  Google Scholar 

  30. Andrews RT. Contrast peripheral phlebography and pulmonary angiography for diagnosis of thromboembolism. Circulation 2004;109:I22–I27.

    Article  PubMed  Google Scholar 

  31. Anderson DR, Kovacs MJ, Kovacs G, et al. Combined use of clinical assessment and d-dimer to improve the management of patients presenting to the emergency department with suspected deep vein thrombosis. Thromb Haemost 2003:635–636.

    Google Scholar 

  32. Stein PD, Hull RD, Patel KC, et al. D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review. Ann Intern Med 2004;140:589–602.

    PubMed  Google Scholar 

  33. Hirsh J, Anand SS, Halperin JL, Fuster V. Guide to anticoagulant therapy: Heparin: a statement for healthcare professionals from the American Heart Association. Circulation 2001;103:2994–3018.

    PubMed  CAS  Google Scholar 

  34. Hirsh J, Fuster V, Ansell J, Halperin JL. American Heart Association/ American College of Cardiology Foundation guide to warfarin therapy. Circulation 2003;107:1692–1711.

    Article  PubMed  Google Scholar 

  35. Raschke RA, Reilly BM, Guidry JR, Fontana JR, Srinivas S. The weight-based heparin dosing nomogram compared with a “standard care” nomogram. A randomized controlled trial. Ann Intern Med 1993;119:874–881.

    PubMed  CAS  Google Scholar 

  36. Quinlan DJ, McQuillan A, Eikelboom JW. Low-molecularweight heparin compared with intravenous unfractionated heparin for treatment of pulmonary embolism: a meta-analysis of randomized, controlled trials. Ann Intern Med 2004;140:175–183.

    PubMed  CAS  Google Scholar 

  37. Gould MK, Dembitzer AD, Doyle RL, Hastie TJ, Garber AM. Low-molecular-weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis. A meta-analysis of randomized, controlled trials. Ann Intern Med 1999;130:800–809.

    PubMed  CAS  Google Scholar 

  38. Buller HR, Davidson BL, Decousus H, et al. Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis: a randomized trial. Ann Intern Med 2004;140:867–873.

    PubMed  Google Scholar 

  39. Kyrle PA, Minar E, Bialonczyk C, Hirschl M, Weltermann A, Eichinger S. The risk of recurrent venous thromboembolism in men and women. N Engl J Med 2004;350:2558–2563.

    Article  PubMed  CAS  Google Scholar 

  40. Schulman S, Rhedin AS, Lindmarker P, et al. A comparison of six weeks with six months of oral anticoagulant therapy after a first episode of venous thromboembolism. Duration of Anticoagulation Trial Study Group. N Engl J Med 1995;332:1661–1665.

    Article  PubMed  CAS  Google Scholar 

  41. Ridker PM, Goldhaber SZ, Danielson E, et al. Long-term, lowintensity warfarin therapy for the prevention of recurrent venous thromboembolism. N Engl J Med 2003;348:1425–1434.

    Article  PubMed  CAS  Google Scholar 

  42. Kearon C, Ginsberg JS, Kovacs MJ, et al. Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism. N Engl J Med 2003;349:631–639.

    Article  PubMed  CAS  Google Scholar 

  43. Schulman S, Wahlander K, Lundstrom T, Clason SB, Eriksson H. Secondary prevention of venous thromboembolism with the oral direct thrombin inhibitor ximelagatran. N Engl J Med 2003;349:1713–1721.

    Article  PubMed  CAS  Google Scholar 

  44. Goldhaber SZ. Prevention of recurrent idiopathic venous thromboembolism. Circulation 2004;110:IV20–IV24.

    PubMed  Google Scholar 

  45. Baglin T, Luddington R, Brown K, Baglin C. Incidence of recurrent venous thromboembolism in relation to clinical and thrombophilic risk factors: prospective cohort study. Lancet 2003;362:523–526.

    Article  PubMed  Google Scholar 

  46. Eichinger S, Minar E, Bialonczyk C, et al. D-dimer levels and risk of recurrent venous thromboembolism. JAMA 2003;290:1071–1074.

    Article  PubMed  CAS  Google Scholar 

  47. Palareti G, Legnani C, Cosmi B, et al. Predictive value of Ddimer test for recurrent venous thromboembolism after anticoagulation withdrawal in subjects with a previous idiopathic event and in carriers of congenital thrombophilia. Circulation 2003;108:313–318.

    Article  PubMed  Google Scholar 

  48. Prandoni P, Lensing AW, Prins MH, et al. Residual venous thrombosis as a predictive factor of recurrent venous thromboembolism. Ann Intern Med 2002;137:955–960.

    PubMed  Google Scholar 

  49. Mohr DN, Silverstein MD, Heit JA, Petterson TM, O’Fallon WM, Melton LJ. The venous stasis syndrome after deep venous thrombosis or pulmonary embolism: a population-based study. Mayo Clin Proc 2000;75:1249–1256.

    Article  PubMed  CAS  Google Scholar 

  50. Brandjes DP, Buller HR, Heijboer H, et al. Randomised trial of effect of compression stockings in patients with symptomatic proximal-vein thrombosis. Lancet 1997;349:759–762.

    Article  PubMed  CAS  Google Scholar 

  51. Prandoni P, Lensing AW, Prins MH, et al. Below-knee elastic compression stockings to prevent the post-thrombotic syndrome: a randomized, controlled trial. Ann Intern Med 2004;141:249–256.

    PubMed  Google Scholar 

  52. Forster A, Wells P. Tissue plasminogen activator for the treatment of deep venous thrombosis of the lower extremity: a systematic review. Chest 2001;119:572–579.

    Article  PubMed  CAS  Google Scholar 

  53. Schweizer J, Kirch W, Koch R, et al. Short-and long-term results after thrombolytic treatment of deep venous thrombosis. J Am Coll Cardiol 2000;36:1336–1343.

    Article  PubMed  CAS  Google Scholar 

  54. Stein PD, Kayali F, Olson RE. Twenty-one-year trends in the use of inferior vena cava filters. Arch Intern Med 2004;164:1541–1545.

    Article  PubMed  Google Scholar 

  55. Decousus H, Leizorovicz A, Parent F, et al. A clinical trial of vena caval filters in the prevention of pulmonary embolism in patients with proximal deep-vein thrombosis. Prevention du Risque d’Embolie Pulmonaire par Interruption Cave Study Group. N Engl J Med 1998;338:409–415.

    Article  PubMed  CAS  Google Scholar 

  56. Stein PD, Alnas M, Skaf E, et al. Outcome and complications of retrievable inferior vena cava filters. Am J Cardiol 2004;94:1090–1093.

    Article  PubMed  Google Scholar 

  57. Lee AY, Levine MN, Baker RI, et al. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med 2003;349:146–153.

    Article  PubMed  CAS  Google Scholar 

  58. Schulman S. Clinical practice. Care of patients receiving long-term anticoagulant therapy. N Engl J Med 2003;349:675–683.

    Article  PubMed  Google Scholar 

  59. Grasso-Correnti N, Goldszer R, Goldhaber SZ. The critical pathways of an anticoagulation service. Crit Pathways Cardiol 2003;2:41–45.

    Article  Google Scholar 

  60. Piazza G, Goldhaber SZ. Periprocedural management of the chronically anticoagulated patient: Critical pathways for bridging therapy. Crit Pathways Cardiol 2003;2:96–103.

    Article  Google Scholar 

  61. Higashi MK, Veenstra DL, Kondo LM, et al. Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. JAMA 2002;287:1690–1698.

    Article  PubMed  CAS  Google Scholar 

  62. Joffe HV, Xu R, Johnson FB, Longtine J, Kucher N, Goldhaber SZ. Warfarin dosing and cytochrome P450 2C9 polymorphisms. Thromb Haemost 2004;91:1123–1128.

    PubMed  CAS  Google Scholar 

  63. Voora D, Eby C, Linder M, al. e. Prospective dosing of warfarin based on cytochrome P-450 2C9 genotype. Thromb Haemost 2005;93:700–705.

    PubMed  CAS  Google Scholar 

  64. Kucher N, Connolly S, Beckman JA, et al. International normalized ratio increase before warfarin-associated hemorrhage: brief and subtle. Arch Intern Med 2004;164:2176–2179.

    Article  PubMed  Google Scholar 

  65. Dorfman D, Goonan E, Boutiller M, Jarolim P, Tanasijevic M, Goldhaber SZ. Point-of-care (POC) versus central laboratory instrumentation for monitoring oral anticoagulation. Vasc Med 2005;10:1–5.

    Article  Google Scholar 

  66. Crowther MA, Douketis JD, Schnurr T, et al. Oral vitamin K lowers the international normalized ratio more rapidly than subcutaneous vitamin K in the treatment of warfarin-associated coagulopathy. A randomized, controlled trial. Ann Intern Med 2002;137:251–254.

    PubMed  CAS  Google Scholar 

  67. Deveras RA, Kessler CM. Reversal of warfarin-induced excessive anticoagulation with recombinant human factor VIIa concentrate. Ann Intern Med 2002;137:884–888.

    PubMed  CAS  Google Scholar 

  68. Goldhaber SZ, Turpie AG. Prevention of venous thromboembolism among hospitalized medical patients. Circulation 2005;111:e1–e3.

    Article  PubMed  Google Scholar 

  69. Samama MM, Cohen AT, Darmon JY, et al. A comparison of enoxaparin with placebo for the prevention of venous thromboembolism in acutely ill medical patients. Prophylaxis in Medical Patients with Enoxaparin Study Group. N Engl J Med 1999;341:793–800.

    Article  PubMed  CAS  Google Scholar 

  70. Leizorovicz A, Cohen AT, Turpie AG, Olsson CG, Vaitkus PT, Goldhaber SZ. Randomized, placebo-controlled trial of dalteparin for the prevention of venous thromboembolism in acutely ill medical patients. Circulation 2004;110:874–879.

    Article  PubMed  CAS  Google Scholar 

  71. Cohen A, Gallus A, Lassen M, et al. Fondaparinux vs. placebo for the prevention of venous thromboembolism in acutely ill medical patients (ARTEMIS). J Thromb Haemost 2003;1:P2046 (abstr).

    Article  Google Scholar 

  72. Kucher N, Koo S, Quiroz R, et al. Electronic alerts to prevent venous thromboembolism among hospitalized patients. N Engl J Med 2005;352:969–977.

    Article  PubMed  CAS  Google Scholar 

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Goldhaber, S.Z. (2007). Venous Disease. In: Willerson, J.T., Wellens, H.J.J., Cohn, J.N., Holmes, D.R. (eds) Cardiovascular Medicine. Springer, London. https://doi.org/10.1007/978-1-84628-715-2_82

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  • DOI: https://doi.org/10.1007/978-1-84628-715-2_82

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