Abstract
Cells under stress produce metallothionein as one way of coping with the biological consequences of that stress. A broad array of conditions are known to elicit increases in metallothionein (MT) synthesis, including exposure to various toxic chemicals [1], increased demands on biosynthetic machinery [2], irradiation [3], psychological stress [4], and inflammation [5]. In each of these circumstances, immune function may also be altered, and these changes may contribute yet further to the conditions that are stressful to cells. Metallothionein produced under these conditions may have important implications for immune function, and for the subsequent susceptibility to further exposure to stress.
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Lynes, M.A. et al. (1999). Metallothionein-mediated alterations in autoimmune disease processes. In: Klaassen, C.D. (eds) Metallothionein IV. Advances in Life Sciences. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8847-9_63
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DOI: https://doi.org/10.1007/978-3-0348-8847-9_63
Publisher Name: Birkhäuser, Basel
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