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Prolactin in Inflammatory Response

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Recent Advances in Prolactin Research

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 846))

Abstract

Prolactin (PRL) is a peptide hormone produced by the pituitary gland and diverse extrapituitary sites, which triggers activation of various signaling pathways after binding to its receptor (PRLr) resulting in the activation of specific genes associated with the pleiotropic activities of PLR. To date, various PRLr isoforms have been described, generated by post-transcriptional or post-translational processes. PRL has been associated with the modulation of a variety of actions in the immune response and inflammatory processes in several physiologic and pathologic conditions. However, PRL can have opposite effects, which might be regulated by interaction with the various isoforms of PRLR and PRL variants, as well as the cellular and molecular microenvironment influence.

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Authors and Affiliations

  1. Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, 44340, Guadalajara, JAL, México

    Ana Laura Pereira Suarez & Priscila A. Martínez Neri

  2. Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco A. C., Av., Normalistas 800, Colinas de la Normal, 44270, Guadalajara, JAL, México

    Gonzalo López-Rincón, Priscila A. Martínez Neri & Ciro Estrada-Chávez

  3. Departamento de Investigación y Desarrollo Laboratorios Virbac América Latina, 44670, Guadalajara, JAL, México

    Gonzalo López-Rincón

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  1. Ana Laura Pereira Suarez
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  2. Gonzalo López-Rincón
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  3. Priscila A. Martínez Neri
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  4. Ciro Estrada-Chávez
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Correspondence to Ciro Estrada-Chávez .

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  1. Department of Biological Sciences, University of Toledo, Toledo, Ohio, USA

    Maria Diakonova, PhD

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Suarez, A., López-Rincón, G., Martínez Neri, P., Estrada-Chávez, C. (2015). Prolactin in Inflammatory Response. In: Diakonova, PhD, M. (eds) Recent Advances in Prolactin Research. Advances in Experimental Medicine and Biology, vol 846. Springer, Cham. https://doi.org/10.1007/978-3-319-12114-7_11

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