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Loop Diuretics and Mortality in Patients with Acute Kidney Injury

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Reducing Mortality in Acute Kidney Injury

Abstract

Critically ill patients are at high risk of fluid retention. Loop diuretics are frequently used for prevention or treatment of volume overload in patients with or at risk for acute kidney injury (AKI). Other indications include hyperkalemia, hypercalcemia, and hyperazotemia. Several trials investigated the impact of loop diuretics on survival in patients with AKI. Their results are mostly inconclusive. The most recent KDIGO guidelines do not recommend the use of loop diuretics for prevention or treatment of AKI.

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Authors and Affiliations

  1. Department of Cardiac Anesthesia and Intensive Care, Silesian Center for Heart Diseases in Zabrze, Medical University of Silesia in Katowice, 9 M. Curie Skłodowska Street, Zabrze, 41-800, Poland

    Łukasz J. Krzych MD, PhD & Piotr Czempik MD

Authors
  1. Łukasz J. Krzych MD, PhD
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  2. Piotr Czempik MD
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Corresponding author

Correspondence to Łukasz J. Krzych MD, PhD .

Editor information

Editors and Affiliations

  1. Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy

    Giovanni Landoni

  2. Cardiac Anesthesia & ICU, AORN Dei Colli, Monaldi Hospital Cardiac Anesthesia & ICU, Naples, Italy

    Antonio Pisano

  3. IRCCS San Raffaele Scientific Institute, Dept of Anesthesia & Intensive care, Milano, Milano, Italy

    Alberto Zangrillo

  4. Austin Hospital, Heidelberg, Victoria, Australia

    Rinaldo Bellomo

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© 2016 Springer International Publishing Switzerland

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Krzych, Ł.J., Czempik, P. (2016). Loop Diuretics and Mortality in Patients with Acute Kidney Injury. In: Landoni, G., Pisano, A., Zangrillo, A., Bellomo, R. (eds) Reducing Mortality in Acute Kidney Injury. Springer, Cham. https://doi.org/10.1007/978-3-319-33429-5_21

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  • DOI: https://doi.org/10.1007/978-3-319-33429-5_21

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-33427-1

  • Online ISBN: 978-3-319-33429-5

  • eBook Packages: MedicineMedicine (R0)

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