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90Y Microspheres: Concepts and Principles

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Liver Radioembolization with 90Y Microspheres

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Why use radiation in the liver at all since it is known to be much more sensitive to radiation damage than the tumors growing in it? This is an excellent and oft-stated question by many in oncology. With the development of internal brachytherapy, the delivery of tumoricidal doses of radiation to tumors of all origins and in all segments of the liver became a reality. Recent advances in medical oncology (anti-angiogenic agents, new systemic chemotherapy agents) have produced encouraging response rates and increased median survivals for many solid tumors. However, despite clearance of disease elsewhere in the body, the liver is usually the site of tumor resistance and ultimately the patient’s death. Moreover, with increased skill and more sophisticated and specialized catheters, today’s interventional radiologists are able to help oncology patients more than ever before. Precise access to the particular artery feeding a chemoinsensitive or unresectable tumor is now a widely available service in most medical centers that treat cancer patients.

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Author information

Authors and Affiliations

  1. PLLC, Wake Radiology Oncology, 300 Ashville Avenue, Suite 110, Cary, NC, 27511, USA

    Andrew S. Kennedy MD, FACRO & William A. Dezarn PhD, DABR

  2. Chapel Hill, School of Medicine, University of North Carolina, Chapel Hill, NC, 27599, USA

    Patrick McNeillie BS, MS1

Authors
  1. Andrew S. Kennedy MD, FACRO
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  2. William A. Dezarn PhD, DABR
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  3. Patrick McNeillie BS, MS1
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Editor information

Editors and Affiliations

  1. Department of Radiology Clínica Universitaria, Universidad de Navarra, Avenida de Pio XII, 36, 31008, Pamplona, Spain

    José I. Bilbao PhD (Professor) (Professor)

  2. Department of Clinical Radiology, University Hospitals - Grosshadern and Innenstadt Ludwig-Maximilians-University of Munich, Marchioninistrasse 15, 81377, Munich, Germany

    Maximilian F. Reiser MD (Professor and Chairman) (Professor and Chairman)

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© 2008 Springer-Verlag Berlin Heidelberg

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Kennedy, A.S., Dezarn, W.A., McNeillie, P. (2008). 90Y Microspheres: Concepts and Principles. In: Bilbao, J.I., Reiser, M.F. (eds) Liver Radioembolization with 90Y Microspheres. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-35423-9_1

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  • DOI: https://doi.org/10.1007/978-3-540-35423-9_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-35421-5

  • Online ISBN: 978-3-540-35423-9

  • eBook Packages: MedicineMedicine (R0)

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