Skip to main content

Urolithiasis

  • Reference work entry
Pediatric Nephrology

Abstract

Urolithiasis is increasingly recognized in pediatric patients and is encountered in a variety of clinical settings: the 8-year-old boy who presents with hematuria, the 14-year old with cystinuria experiencing her fourth episode of renal colic in the past 6 years, the 10-year old with inflammatory bowel disease whose two renal stones were recognized incidentally during imaging for evaluation of abdominal pain, the premature infant with asymptomatic nephrocalcinosis and a stone, the 4-year old in the emergency room with gross hematuria and abdominal pain after recently starting indinavir medication. All have in common particulate material of mineral origin within the urinary tract. An understanding of how and why stones form, along with knowledge of the pathophysiologic states that promote urinary tract calculi, provide the basis for effective clinical management.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 369.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Walther PC, Lamm D, Kaplan GW. Pediatric urolithiasis: a 10-year review. Pediatrics 1980;65:1068–1072.

    PubMed  CAS  Google Scholar 

  2. Troup CW, Lawnicki CC, Bourne RB et al. Renal calculus in children. J Urol 1972;107:306–307.

    PubMed  CAS  Google Scholar 

  3. Nimkin K, Lebowitz RL, Share JC et al. Urolithiasis in a children’s hospital: 1985–1990. Urol Radiol 1992;14:139–143.

    Article  PubMed  CAS  Google Scholar 

  4. Polinsky MS, Kaiser BA, Baluarte HJ. Urolithiasis in childhood. Pediatr Clin North Am 1987;34:683–710.

    PubMed  CAS  Google Scholar 

  5. Pearle MS, Calhoun EA, Curhan GC. Urologic diseases in America project: urolithiasis. J Urol 2005;173:848–857.

    Article  PubMed  Google Scholar 

  6. Milliner DS. Epidemiology of calcium oxalate urolithiasis in man. In: Calcium Oxalate in Biological Systems. Kahn S (ed.). Boca Raton, FL, CRC Press.(1995)

    Google Scholar 

  7. Miyake O, Kakimoto K, Tsujihata M et al. Strong inhibition of crystal-cell attachment by pediatric urinary macromolecules: a close relationship with high urinary citrate secretion. Urol 2001;58:493–497.

    Article  PubMed  CAS  Google Scholar 

  8. Miyake O, Yoshimura K, Yoshioka T et al. High urinary excretion level of citrate and magnesium in children: potential etiology for the reduced incidence of pediatric urolithiasis. Urol Res 1998;26:290–213.

    Article  Google Scholar 

  9. Fujisawa M, Morikawa M, Arima S et al. Analysis of the urinary risk factors of urolithiasis in healthy children. Jap J Urol 1989;80:1187–1194.

    PubMed  CAS  Google Scholar 

  10. Bergsland KJ, Kinder JM, Asplin JR et al. Influence of gender and age on calcium oxalate crystal growth inhibition by urine from relatives of stone forming patients. J Urol 2002;167:2372–2376.

    Article  PubMed  CAS  Google Scholar 

  11. Robertson WG, Peacock M, Heyburn PJ. Risk factors in calcium stone disease of the urinary tract. Br J Urol 1978;50:449–454.

    Article  PubMed  CAS  Google Scholar 

  12. Milliner DS, Murphy ME. Urolithiasis in pediatric patients. Mayo Clinic Proc 1993;68:241–248.

    Article  CAS  Google Scholar 

  13. Lim DJ, Walker RDIII, Ellsworth PI et al. Treatment of pediatric urolithiasis between 1984 and 1994. J Urol 1996;156:702–705.

    Article  PubMed  CAS  Google Scholar 

  14. Choi H, Snyder HM, Duckett JW. Urolithiasis in childhood: current management. J Pediatr Surg 1987;22:158–164.

    Article  PubMed  CAS  Google Scholar 

  15. Pietrow PK, Pope JC, Adams MC et al. Clinical outcome of pediatric stone disease. J Urol 2002;167:670–673.s

    Article  PubMed  Google Scholar 

  16. Gearhart JP, Herzberg GZ, Jeffs RD. Childhood urolithiasis: experiences and advances. Pediatr 1991;87:445–450.

    CAS  Google Scholar 

  17. Diamond DA. Clinical patterns of paediatric urolithiasis. Br J Urol 1991;68:195–198

    Article  PubMed  CAS  Google Scholar 

  18. Perrone HC, dos Santos DR, Santos MV et al. Urolithiasis in childhood: metabolic evaluation. Pediatr Nephrol 1992;6:54–56.

    Article  PubMed  CAS  Google Scholar 

  19. Sarkissian A, Baloyan A, Arikyants N et al. Pediatric urolithiasis in Armenia: a study of 198 patients observed from 1991 to 1999. Pediatr Nephrol 2001;16:728–732.

    Article  PubMed  CAS  Google Scholar 

  20. Taylor EN, Curhan GC. Differences in 24-hour urine composition between black and white women. J Am Soc Nephrol 2007;18:654–659.

    Article  PubMed  CAS  Google Scholar 

  21. Rodgers AL, Lewandowski S. Effects of 5 different diets on urinary risk factors for calcium oxalate kidney stone formation: evidence of different renal handling mechanisms in different race groups. J Urol 2002;168:931–936.

    Article  PubMed  Google Scholar 

  22. Stamatelou KK, Francis ME, Jones CA, Nyberg LM et al. Time trends in reported prevalence of kidney stones in the United States: 1976–1994. Kidney Int 2003;63:1817–1823.

    Article  PubMed  Google Scholar 

  23. Stapleton FB. Clinical approach to children with urolithiasis. Semin Nephrol 1996;16:389–397.

    PubMed  CAS  Google Scholar 

  24. Kraus SJ, Lebowitz RL, Royal SA. Renal calculi in children: imaging features that lead to diagnoses: a pictorial essay. Pediatr Radiol 1999;29:624–630.

    Article  PubMed  CAS  Google Scholar 

  25. Robertson WG. What is the aetiology of urinary calculi? Pediatr Nephrol 1996;10:763.

    PubMed  CAS  Google Scholar 

  26. Anderson DA. The nutritional significance of primary bladder stones. British J Urol 1962;34:160.

    Article  Google Scholar 

  27. Ashworth M. Endemic bladder stones. British Med J 1990;301:826–827.

    Article  CAS  Google Scholar 

  28. Stapleton FB, McKay CP, Noe HN. Urolithiasis in children: the role of hypercalciuria. Pediatr Ann 1987;16:980–992.

    PubMed  CAS  Google Scholar 

  29. Stapleton FB, Linshaw MA, Hassanein K, et al. Uric acid excretion in normal children. J Pediatr 1978;92:911–914

    Article  PubMed  CAS  Google Scholar 

  30. Morgenstern BZ, Milliner DS, Murphy ME et al. Urinary oxalate and glycolate excretion patterns in the first year of life: A longitudinal study. J Pediatr 1993;123:248–251.

    Article  PubMed  CAS  Google Scholar 

  31. von Schnakenburg C, Byrd DJ, Latta K et al. Determination of oxalate excretion in spot urines of healthy children by ion chromatography. Eur J Clin Chem Clin Biochem 1994;32:27–29.

    Google Scholar 

  32. Gibbs DA, Watts RW. The variation of urinary oxalate excretion with age. J Lab Clin Med 1969;73:901–908.

    PubMed  CAS  Google Scholar 

  33. Stapleton FB, Nash DA. A screening test for hyperuricosuria. J Pediatr 1983;102:88–90.

    Article  PubMed  CAS  Google Scholar 

  34. Butani L, Kalia A. Idiopathic hypercalciuria in children – how valid are the existing diagnostic criteria? Pediatr Nephrol 2004;19:577–582.

    Article  PubMed  Google Scholar 

  35. Smith SL, Somers JM, Broderick N et al. The role of the plain radiograph and renal tract ultrasound in the management of children with renal tract calculi. Clin Radiol 2000;55:708–710.

    Article  PubMed  CAS  Google Scholar 

  36. Diament MJ, Malekzadeh M. Ultrasound and the diagnosis of renal and ureteral calculi. J Pediatr 1986;109:980–983.

    Article  PubMed  CAS  Google Scholar 

  37. Vrtiska TJ, Hattery RR, King BF et al. Role of ultrasound in medical management of patients with renal stone disease. Urol Radiol 1992;14:131–138.

    Article  PubMed  CAS  Google Scholar 

  38. Smergel E, Greenberg SB, Crisci KL et al. CT urograms in pediatric patients with ureteral calculi: do adult criteria work? Pediatr Radiol 2001;31:720–723.

    Article  PubMed  CAS  Google Scholar 

  39. Brenner DJ, Elliston C, Hall E et al. Estimated risks of radiation-induced fatal cancer from pediatric CT. Am J Radiol 2001;176:289–296.

    CAS  Google Scholar 

  40. Donnelly LF, Emery KH, Brody AS et al. Minimizing radiation dose for pediatric body applications of single detector helical CT: strategies at a large children’s hospital. Am J Radiol 2001;176:303–306

    CAS  Google Scholar 

  41. Rosser CJ, Zagoria R, Dixon R et al. Is there a learning curve in diagnosing urolithiasis with noncontrast helical computed tomography? Can Assoc Radiol J 2000;51:177–181.

    PubMed  CAS  Google Scholar 

  42. Singh A, Alter HJ, Littlepage A. A systematic review of medical therapy to facilitate passage of ureteral calculi. Ann Emerg Med 2007;50:552–563.

    Article  PubMed  Google Scholar 

  43. Parsons JK, Hergan LA, Sakamoto K et al. Efficacy of alpha-blockers for the treatment of ureteral stones. J Urol 2007;177:983–987.

    Article  PubMed  CAS  Google Scholar 

  44. Bernardo N, Smith A. Chemolysis of urinary calculi. Urol Clin N Am 2000;27:355.

    Article  CAS  Google Scholar 

  45. Smaldone MC, Cannon GM, Wu HY. Is ureteroscopy first line treatment for pediatric stone disease? J Urol 2007;178:2128–2131.

    Article  PubMed  Google Scholar 

  46. Reisiger K, Vardi I, Yan Y. Pediatric nephrolithiasis: does treatment affect renal growth? Pediatr Urol 2007;69:1190–1194.

    Article  Google Scholar 

  47. Schuster TG, Russell KY, Bloom DA. Ureteroscopy for the treatment of urolithiasis in children. J Urol 2002;167:1813–1816.

    Article  PubMed  Google Scholar 

  48. Thomas JC, DeMarco RT, Donohoe JM et al. Management of the failed pyeloplasty: a contemporary review. J Urol 2005;174:2363–2366.

    Article  PubMed  CAS  Google Scholar 

  49. Villanyi KK, Szekely JG, Farkas LM et al. Short-term changes in renal function after extracorporeal shock wave lithotripsy in children. J Urol 2001;166:222–224.

    Article  PubMed  CAS  Google Scholar 

  50. Lifshitz DA, Lingeman JE, Zafar FS et al. Alterations in predicted growth rate of pediatric kidneys treated with extracorporeal shock wave lithotripsy. J Endourol 1998;12:469–475.

    Article  PubMed  CAS  Google Scholar 

  51. Brinkman OA, Griehl A, Kuwertz-Broking E et al. Extracorporeal shock wave lithotripsy in children. Eur Urol 2001;39:591–597.

    Article  Google Scholar 

  52. Wadhwa P, Aron M, Bal CS, et al. Critical prospective appraisal of renal morphology and function in children undergoing shockwave lithotripsy and percutaneous nephrolithotomy. J Endourol 2007;21:961–966.

    Article  PubMed  Google Scholar 

  53. Lottmann HB, Archambaud F, Traxer O et al. The efficacy and parenchymal consequences of extracorporeal shock wave lithotripsy in infants. BJU Int 2000;85:311–315.

    Article  PubMed  CAS  Google Scholar 

  54. Griffith DP, Gleeson MJ, Lee H. Randomized, double-blind trial of Lithostat (acetohydroxamine acid) in the palliative treatment of infection-induced urinary calculi. Eur Urol 1991;20:243–247.

    PubMed  CAS  Google Scholar 

  55. Curhan GC, Willett WC, Rimm EB et al. A prospective study of dietary calcium and other nutrients and the risk of symptomatic kidney stones. N Engl J Med 1993;328:833–838.

    Article  PubMed  CAS  Google Scholar 

  56. Alon US, Berenbom A. Idiopathic hypercalciuria of childhood: 4- to 11-year outcome. Pediatr Nephrol 2000;14:1011–1015.

    Article  PubMed  CAS  Google Scholar 

  57. Muldowney FR, Freaney R, Moloney MF. Importance of dietary sodium in the hypercalciuria syndrome. Kidney Int 1982;22:292–296.

    Article  PubMed  CAS  Google Scholar 

  58. Jaeger P, Portmann L, Saunders L et al. Anticystinuric effects of glutamine and of dietary sodium restriction. N Engl J Med 1986;315:1120–1123.

    Article  PubMed  CAS  Google Scholar 

  59. Norman RW, Manette WA. Dietary restriction of sodium as a means of reducing urinary cystine. J Urol 1990;143:1193–1195.

    PubMed  CAS  Google Scholar 

  60. Peces R, Sanchez L, Gorostidi M et al. Effects in variation in sodium intake on cystinuria. Nephron 1991;57:421–423.

    Article  PubMed  CAS  Google Scholar 

  61. Rodriguez LM, Santos F, Malaga S et al. Effect of a low sodium diet on urinary elimination of cystine in cystinuric children. Nephron 1995;71:416–418.

    Article  PubMed  CAS  Google Scholar 

  62. Khan SR, Glenton PA, Backov R et al. Presence of lipids in urine, crystals and stones: implications for the formation of kidney stones. Kidney Int 2002;62:2062–2072.

    Article  PubMed  CAS  Google Scholar 

  63. Pak CYC, Arnold LH. Heterogenous nucleation of calcium oxalate by seeds of monosodium urate. Proc Soc Exp Biol Med 1975;149:930–932.

    PubMed  CAS  Google Scholar 

  64. Fleisch H. Inhibitors and promoters of stone formation. Kidney Int 1978;13:361–371.

    Article  PubMed  CAS  Google Scholar 

  65. Pak CY. Potential etiologic role of brushite in the formation of calcium (renal) stones. J Crystal Growth 1981;53:202–208.

    Article  CAS  Google Scholar 

  66. Coe FL, Kavalach AG. Hypercalciuria and hyperuricosuria in patients with calcium nephrolithiasis. N Engl J Med 1974;291:1344–1350.

    Article  PubMed  CAS  Google Scholar 

  67. Lingeman JE, Smith LH, Wood JR et al. Basic considerations of urinary stone formation. In: Urinary Calculi. ESWL, Endourology and Medical Theraphy. Moster MB (ed.). Philadelphia, PA, Lea & Febiger, 1989:51–76.

    Google Scholar 

  68. Burdette DC, Thomas WC, Finlayson B. Urinary supersaturation with calcium oxalate before and during orthophosphate therapy. J Urol 1976;115:418–422.

    PubMed  CAS  Google Scholar 

  69. Pak CYC, Fuller C, Sakhaee K et al. Long-term treatment of calcium nephrolithiasis with potassium citrate. J Urol 1985;134:11–19.

    PubMed  CAS  Google Scholar 

  70. Sayer JA, Carr G, Simmons NL. Nephrocalcinosis: molecular insights into calcium precipitation within the kidney. Clin Sci 2004;106:549–561.

    Article  PubMed  CAS  Google Scholar 

  71. Ronnefarth G, Misselwitz J. Nephrocalcinosis in children: a retrospective survey. Pediatr Nephrol 2000;14:1016–1021.

    Article  PubMed  CAS  Google Scholar 

  72. Noe HN, Stapleton FB, Jerkins GR et al. Clinical experience with pediatric urolithiasis. J Urol 1983;129:1166–1168.

    PubMed  CAS  Google Scholar 

  73. Basaklar AC, Kale N. Experience with childhood urolithiasis. Report of 196 cases. British J Urol 1991;67:203–205.

    Article  CAS  Google Scholar 

  74. Coward RJ, Peters CJ, Duffy PG et al. Epidemiology of paediatric renal stone disease in the UK. Arch Dis Child 2003;88:962.

    Article  PubMed  CAS  Google Scholar 

  75. Ryall RL. Glycosaminoglycans, proteins, and stone formation: adult themes and child’s play. Pediatr Nephrol 1996;10:656–666.

    Article  PubMed  CAS  Google Scholar 

  76. Srivastava T, Alon US. Pathophysiology of hypercalciuria in children. Pediatr Nephrol 2007;22:1659–1673.

    Article  PubMed  Google Scholar 

  77. Vachvanichsanong P, Malagon M, Moore ES. Urinary tract infection in children associated with idiopathic hypercalciuria. Scand J Urol Nephrol 2001;35:112–116.

    Article  PubMed  CAS  Google Scholar 

  78. Stapleton FB. Idiopathic hypercalciuria: association with isolated hematuria and risk for urolithiasis in children. Kidney Int 1990;37:807–811.

    Article  PubMed  CAS  Google Scholar 

  79. Garcia CD, Miller LA, Stapleton FB. Natural history of hematuria associated with hypercalciuria in children. Am J Dis Child 1991;145:1204–1207.

    PubMed  CAS  Google Scholar 

  80. Polito C, La Manna A, Cioce F et al. Clinical presentation and natural course of idiopathic hypercalciuria in children. Pediatr Nephrol 2000;15:211–214.

    Article  PubMed  CAS  Google Scholar 

  81. Coe FL, Parks JH, Moore ES. Familial idiopathic hypercalciuria. N Engl J Med 1979;300:337–340.

    Article  PubMed  CAS  Google Scholar 

  82. Mehes K, Szelid Z. Autosomal dominant inheritance of hypercalciuria. Eur J Pediatr 1980;133:239–242.

    Article  PubMed  CAS  Google Scholar 

  83. Harangi F, Méhes K. Family investigations in idiopathic hypercalciuria. Eur J Pediatr 1993;152:64–68.

    Article  PubMed  CAS  Google Scholar 

  84. Goodman JO, Holmes RP, Assimos DG. Genetic factors in calcium oxalate stone disease. J Urol 1995;153:301–307.

    Article  PubMed  CAS  Google Scholar 

  85. Gambaro G, Vezzoli G, Casari G et al. Genetics of hypercalciuria and calcium nephrolithiasis: from the rare monogenic to the common polygenic forms. Am J Kidney Dis 2004;44:963–986.

    Article  PubMed  CAS  Google Scholar 

  86. Frick KK, Bushinsky DA. Molecular mechanisms of primary hypercalciuria. J Am Soc Nephrol 2003;14:1082–1095.

    Article  PubMed  Google Scholar 

  87. Freundlich M, Alonzo E, Bellorin-Font E, Weisinger JR. Reduced bone mass in children with idiopathic hypercalciuria and in their asymptomatic mothers. Nephrol Dial Transplant 2002;17:1396–1401.

    Google Scholar 

  88. Misael da Silva AM, dos Reis LM, Pereira RC et al. Bone involvement in idiopathic hypercalciuria. Clin Nephrol 2002;57:183–191.

    PubMed  CAS  Google Scholar 

  89. Langman CB, Schmeissing KJ, Sailer DM. Children with genetic hypercalciuria exhibit thiazide-response osteopenia. Pediatr Res 35 1994;368A.

    Google Scholar 

  90. Prie D, Ravery V, Boccon-Gibod L et al. Frequency of renal phosphate leak among patients with calcium nephrolithiasis. Kidney Int 2001;60:272–276.

    Article  PubMed  CAS  Google Scholar 

  91. Devuyst O, Christie PT, Courtoy PJ et al. Intra-renal and subcellular distribution of the human chloride channel, CLC-5, reveals a pathophysiological basis for Dent’s disease. Hum Mol Genet 1999;8:247–257.

    Article  PubMed  CAS  Google Scholar 

  92. Scheinman SJ. X-linked hypercalciuric nephrolithiasis: clinical syndromes and chloride channel mutations. Kidney Int 1998;53:3–17.

    Article  PubMed  CAS  Google Scholar 

  93. Lloyd SE, Gunther W, Pearce SHS et al. Characterisation of renal chloride channel CLCN5, mutations in hypercalciuric nephrolithiasis (kidney stones) disorders. Hum Mol Gen 1997;6:1233–1239.

    Article  PubMed  CAS  Google Scholar 

  94. Raja KA, Schurman S, D’Mello RG et al. Responsiveness of hypercalciuria to thiazide in Dent’s disease. J Am Soc Nephrol 2002;13:2938–2944.

    Article  PubMed  Google Scholar 

  95. Norden AGW, Scheinman SJ, Deschodt-Lanckman MM et al. Tubular proteinuria defined by a study of Dent’s (CLCN5 mutation) and other tubular diseases. Kidney Int 2000;57:240–249.

    Article  PubMed  CAS  Google Scholar 

  96. Langlois V, Bernard C, Scheinman SJ et al. Clinical features of X-linked nephrolithiasis in childhood. Pediatr Nephrol 12:625–629.

    Google Scholar 

  97. Bohles H, Brandl U, Schott G et al. Clinical and chemical factors in kidney calculus formation in childhood. An analysis of 40 patients. Monatsschrift Kinderheilkunde 1984;132:158–162.

    PubMed  CAS  Google Scholar 

  98. Neuhaus TJ, Belzer T, Blau N et al. Urinary oxalate excretion in urolithiasis and nephrocalcinosis. Arch Dis Child 2000;82:322–326.

    Article  PubMed  CAS  Google Scholar 

  99. Smith LH. Diet and hyperoxaluria in the syndrome of idiopathic calcium oxalate urolithiasis. Am J Kidney Dis 1991;17:370–375.

    PubMed  CAS  Google Scholar 

  100. Hatch M. Oxalate status in stone-formers. Urol Res 1993;21:55–59.

    Article  PubMed  CAS  Google Scholar 

  101. Hesse A, Schneeberger W, Engfeld S et al. Intestinal hyperabsorption of oxalate in calcium oxalate stone formers: application of a new test with [13C2] oxalate. J Am Soc Nephrol 1999;10:S329–S333.

    PubMed  CAS  Google Scholar 

  102. Williams HE, Wandzilak TR. Oxalate synthesis, transport, and the hyperoxaluric syndromes. J Urol 1989;141:742–749.

    PubMed  CAS  Google Scholar 

  103. Holmes RP, Goodman HO, Assimos DG. Contribution of dietary oxalate to urinary oxalate excretion. Kidney Int 2001;59:270–276.

    Article  PubMed  CAS  Google Scholar 

  104. Chen CL, Fang HC, Chou KJ et al. Acute oxalate nephropathy after ingestion of star fruit. Am J Kidney Dis 2001;37:418–422.

    Article  PubMed  CAS  Google Scholar 

  105. Hoppe B, Hesse A, Bromme S et al. Urinary excretion substances in patients with cystic fibrosis: risk of urolithiasis? Pediatr Nephrol 1998;12:275–279.

    Article  PubMed  CAS  Google Scholar 

  106. Monico CG, Ford GC, Persson XMT et al. Potential mechanisms of marked hyperoxaluria not due to primary hyperoxaluria I or II. Kidney Int 2002;62:392–400.

    Article  PubMed  CAS  Google Scholar 

  107. Sidhu H, Hoppe B, Hesse A et al. Absence of Oxalobacter formigenes in cystic fibrosis patients: a risk factor for hyperoxaluria. Lancet 1998;352:1026–1029.

    Article  PubMed  CAS  Google Scholar 

  108. Kumar R, Mukherjee M, Bhandari M et al. Role of Oxalobacter formigenes in calcium oxalate stone disease: a study from North India. Eur Urol 2002;41:318–322.

    Article  PubMed  CAS  Google Scholar 

  109. Kaufman DW, Kelly JP, Curhan GC et al. 2008;Oxalobacter formigenes may reduce the risk of calcium oxalate kidney stones. J Am Soc Nephrol doi: 10.1681.

    Google Scholar 

  110. Lieske JC, Goldfarb DS, de Simone C et al. Use of a probiotic to decrease enteric hyperoxaluria. Kidney Int 2005;68:1244–1249.

    Article  PubMed  CAS  Google Scholar 

  111. Danpure CJ. Primary hyperoxaluria. In: The Metabolic and Molecular Bases of Inherited Disease, 8th edn. Schriver CR, Beaudet AL, Sly WS, Valle D, Childs B (eds.). New York, McGraw-Hill, 2001.

    Google Scholar 

  112. Giafi CF, Rumsby G. Primary hyperoxaluria type 2: enzymology. J Nephrol 1998;11:29–31.

    PubMed  Google Scholar 

  113. Cochat P, Deloraine A, Rotily M et al. Epidemiology of primary hyperoxaluria type I. Nephrol Dial Transplant 1995;10:3–7.

    Article  PubMed  Google Scholar 

  114. Van Acker KJ, Eyskens FJ, Espeel MF et al. Hyperoxaluria with hyperglycoluria not due to alanine:glyoxylate aminotransferase defect: a novel type of primary hyperoxaluria. Kidney Int 1996;50:1747–1752.

    Article  PubMed  CAS  Google Scholar 

  115. Monico CG, Rossetti S, Schwanz H et al. Comprehensive mutation screening in 55 type 1 primary hyperoxaluria probands shows feasibility of a gene-based diagnosis. J Am Soc Nephrol 2007;18:1905–1914.

    Article  PubMed  CAS  Google Scholar 

  116. Milliner DS. Diagnostic algorithm for the primary hyperoxalurias. Am J Nephrol 2005;25:154–160.

    Article  PubMed  Google Scholar 

  117. Milliner DS, Wilson DM, Smith LH. Phenotypic expression of primary hyperoxaluria: comparative features of types I and II. Kidney Int 2001;59:31–3.

    Article  PubMed  CAS  Google Scholar 

  118. Milliner DS, Eickholt JT, Bergstralh EJ et al. Primary hyperoxaluria: results of long-term treatment with orthophosphate and pyridoxine. New Engl J Med 1994;331:1553–1558.

    Article  PubMed  CAS  Google Scholar 

  119. Cochat P, Koch Nogueira PC, Mahmoud MA et al. Primary hyperoxaluria in infants: medical, ethical, and economic issues. J Pediatr 1999;135:746–750.

    Article  PubMed  CAS  Google Scholar 

  120. Toussaint C. Pyridoxine-responsive PHI: treatment. J Nephrol 1998;11:49–50.

    PubMed  Google Scholar 

  121. Smith LH, Werness PG, VandenBerg CJ et al. Orthophosphate treatment in calcium urolithiasis. Scand J Urol Nephrol 53:253–263.

    Google Scholar 

  122. Leumann E, Hoppe B, Neuhaus TJ. Management of primary hyperoxaluria: effect of oral citrate administration. Pediatr Nephrol 1993;7:207–211.

    Article  PubMed  CAS  Google Scholar 

  123. Hoppe B, Beck B, Gatter N et al. Oxalobacter formigenes: a potential tool for the treatment of primary hyperoxaluria type 1. Kidney Int 2006;70:1305–1311.

    Article  PubMed  CAS  Google Scholar 

  124. Milliner DS. Treatment of the primary hyperoxalurias: a new chapter. Kidney Int 2006;70:1198–1200.

    Article  PubMed  CAS  Google Scholar 

  125. Hatch M, Cornelius J, Allison M et al. Oxalobacter sp. Reduces urinary oxalate excretion by promoting enteric oxalate excretion. Kidney Int 2006;69:691–698.

    Article  PubMed  CAS  Google Scholar 

  126. Dent CE, Senor B. Studies on the treatment of cystinuria. Brit J Urol 1955;27:317–332.

    Article  PubMed  CAS  Google Scholar 

  127. Bruno M, Marangella M. Cystinuria: recent advances in pathophysiology and genetics. Contrib Nephrol 1997;122:173–177.

    Article  PubMed  CAS  Google Scholar 

  128. Goodyer P, Boutros M, Rozen R. The molecular basis of cystinuria: an update. Exp Nephrol 2000;8:123–127.

    Article  PubMed  CAS  Google Scholar 

  129. Scriver CR. Cystinuria. N Engl J Med 1986;315:1155–1157.

    Article  PubMed  CAS  Google Scholar 

  130. Goodyer P, Saadi I, Ong P et al. Cystinuria subtype and the risk of nephrolithiasis. Kidney Int 1998;54:56–61.

    Article  PubMed  CAS  Google Scholar 

  131. Purroy J, Bisceglia L, Calonge MJ et al. Genomic structure and organization of the human rbat gene (SLC3A1). Genomics 1996;37:249–252.

    Article  PubMed  CAS  Google Scholar 

  132. Chesney RW. Mutational analysis of patients with cystinuria detected by a genetic screening network: powerful tools in understanding the several forms of the disorder. Kidney Int 1998;54:279–280.

    Article  PubMed  CAS  Google Scholar 

  133. Rosenberg LE, Downing SJ, Durant JL et al. Cystinuria: biochemical evidence for three genetically distinct diseases. J Clin Invest 1966;45:365–371.

    Article  PubMed  CAS  Google Scholar 

  134. Feliubadalo L, Font M, Purroy J et al. Non-type I cystinuria caused by mutations in SLC7A9, encoding a subunit (b(,+ AT) of rbat. Nature Genet 1999;23:52–57.

    PubMed  CAS  Google Scholar 

  135. Strologo LD, Pras E, Pontesilli C et al. Comparison between SLC3A1 and SLC7A9 cystinuria patients and carriers: a need for a new classification. J Am Soc Nephrol 2002;13:2547–2553.

    Article  Google Scholar 

  136. Font-Llitjos M, Jimenez-Vidal M, Bisceglia L et al. New insights into cystinuria: 40 new mutations, genotype-phenotype correlation, and digenic inheritance causing partial phenotype. J Med Genet 2005;42:58–68.

    Article  PubMed  CAS  Google Scholar 

  137. Goodyer PR, Clow C, Reade T et al. Prospective analysis and classification of patients with cystinuria identified in a newborn screening program. J Pediatr 1993;122:568–572.

    Article  PubMed  CAS  Google Scholar 

  138. Becker G. Cystine stones. Nephrology 2007;12:S4–S10.

    Article  PubMed  CAS  Google Scholar 

  139. Dello Strologo L, Laurenzi C, Legato A et al. Cystinuria in children and young adults: success of monitoring free-cystine urine levels. Pediatr Nephrol 2007;22:1869–1873.

    Article  PubMed  Google Scholar 

  140. Pak CY, Fuller C, Sakhaee K et al. Management of cystine nephrolithiasis with alpha-mercaptopropionylglycine. J Urol 1986;136:1003–1008.

    PubMed  CAS  Google Scholar 

  141. Milliner DS. cystinuria. In: Endocrinology and Metabolism Clinics of North America. Smith LH (ed.). Philadelphia, PA, WB Saunders.(1990)

    Google Scholar 

  142. Jaeger P. cystinuria. In: Inherited Disorders of the Kidney. Morgan SH, Grunfeld JP (eds.). New York, Oxford University, 1998.

    Google Scholar 

  143. Stapleton FB. Hematuria associated with hypercalciuria and hyperuricosuria: a practical approach. Pediatr Nephrol 1994;8:756–761.

    Article  PubMed  CAS  Google Scholar 

  144. La Manna A, Polito C, Marte A et al. Hyperuricosuria in children: clinical presentation and natural history. Pediatrics 2001;107:86–90.

    Article  PubMed  CAS  Google Scholar 

  145. Baldree LA, Stapleton FD. Uric acid metabolism in children. Pediatr Clin North Am 1990;2:391–418.

    Google Scholar 

  146. Benjamin D, Sperling O, Weinberger A. Familial hypouricemia due to isolated renal tubular defect. Nephron 1977;18:220–225.

    Article  PubMed  CAS  Google Scholar 

  147. Furth SL, Casey JC, Pyzik PL et al. Risk factors for urolithiasis in children on the ketogenic diet. Pediatr Nephrol 2000;15:125–128.

    Article  PubMed  CAS  Google Scholar 

  148. Padova J, Pachevsky A, Onesti G. The effect of glucose loads on renal uric acid secretion in diabetic patients. Metabolism 1964;28:472–476.

    Google Scholar 

  149. Beck LH. Hypouricemia in the syndrome of inappropriate secretion of antidiuretic hormone. N Engl J Med 1979;301:528–530.

    Article  PubMed  CAS  Google Scholar 

  150. Greene ML, Fujimoto WY, Seegmiller JE. Urinary xanthine stones: a rare complication of allopurinol therapy. N Engl J Med 1969;280:426–427.

    Article  PubMed  CAS  Google Scholar 

  151. Carpenter TO, Lebowitz L, Nelson D et al. Hereditary xanthinuria presenting in infancy with nephrolithiasis. J Pediatr 1986;109:307–309.

    Article  PubMed  CAS  Google Scholar 

  152. Zibolen M, Srsnova K, Srsen S. Increased urolithiasis in patients with alkaptonuria in childhood. Clin Genet 2000;58:79–80.

    Article  PubMed  CAS  Google Scholar 

  153. Simmonds HA, Sahota AS, Van Acker KJ. Adenine phosphoribosyltransferase deficiency and 2,8-dihydroxyadenine urolithiasis. In: The Metabolic and Molecular Bases of Inherited Disease, 7th edn. Scriver CR (ed.). New York, McGraw-Hill, 1995.

    Google Scholar 

  154. Edvardsson V, Palsson R, Olafsson I et al. Clinical features and genotype of adenine phosphoribosyltransferase deficiency in Iceland. Am J Kidney Dis 2001;38:473–480.

    Article  PubMed  CAS  Google Scholar 

  155. Parks JH, Coe FL. A urinary calcium-citrate index for the evaluation of nephrolithiasis. Kidney Int 1986;30:85–90

    Article  PubMed  CAS  Google Scholar 

  156. Tekin A, Tekgul S, Atsu N et al. A study of the etiology of idiopathic calcium urolithiasis in children: hypocitruria is the most important risk factor. J Urol 2000;164:162–165.

    Article  PubMed  CAS  Google Scholar 

  157. Baggio B, Gambaro G, Favaro S, et al. Juvenile renal stone disease: a study of urinary promoting and inhibiting factors. J Urol 1983;130:1133–1135.

    PubMed  CAS  Google Scholar 

  158. Akcay T, Konukolu D, Dincer Y. Urinary glycosaminoglycan excretion in urolithiasis. Arch Dis Child 1999;80:271–272.

    Article  PubMed  CAS  Google Scholar 

  159. Ryall RL. Glycosaminoglycans, proteins, and stone formation: adult themes and child’s play. Pediatr Nephrol 1996;10:656–666.

    Article  PubMed  CAS  Google Scholar 

  160. Wagner CA. When proton pumps go sour: urinary acidification and kidney stones. Kidney Int 2008;73:1103–1105.

    Article  PubMed  CAS  Google Scholar 

  161. Caldas A, Broyer M, Duchaux M et al. Primary distal tubular acidosis in childhood: clinical study and long-term follow-up of 28 patients. J Pediatr 1992;121:233–241.

    Article  PubMed  CAS  Google Scholar 

  162. Brenner RJ, Spring DB, Sebastian A et al. Incidence of radiographically evident bone disease, nephrocalcinosis, and nephrolithiasis in various types of renal tubular acidosis. New Engl J Med 1982; 307:217–221.

    Google Scholar 

  163. Santos F, Chan JCM. Renal tubular acidosis in children. Am J Nephrol 1986;6:289–295.

    Article  PubMed  CAS  Google Scholar 

  164. Buckalew VM, Purvis ML, Shulman MG et al. Hereditary renal tubular acidosis. Med 1974;53:229–254.

    Google Scholar 

  165. Ismail EAR, Saad SA, Sabry MA. Nephrocalcinosis and urolithiasis in carbonic anhydrase II deficiency syndrome. Eur J Pediatr 1997;156:957–962.

    Article  PubMed  CAS  Google Scholar 

  166. Strisciuglio P, Hu PY, Lim EJ et al. Clinical and molecular heterogeneity in carbonic anhydrase II deficiency and prenatal diagnosis in an Italian family. J Pediatr 1998;132:717–720.

    Article  PubMed  CAS  Google Scholar 

  167. Nagai R, Kooh SW, Balfe JW et al. Renal tubular acidosis and osteopetrosis with carbonic anhydrase II deficiency: pathogenesis of impaired acidification. Pediatr Nephrol 1997;11:633–636.

    Article  PubMed  CAS  Google Scholar 

  168. Bruce LJ, Unwin RJ, Wrong O et al. The association between familial distal renal tubular acidosis and mutations in the red cell anion exchanger (band 3, AE1) gene. Biochem Cell Biol 1998;76:723–728.

    PubMed  CAS  Google Scholar 

  169. Karet FE, Gainza FJ, Gyory AZ et al. Mutations in the chloride-bicarbonate exchanger gene AE1 cause autosomal dominant but not autosomal recessive distal renal tubular acidosis. Proc Natl Acad Sci USA 1998;95:6337–6342.

    Article  PubMed  CAS  Google Scholar 

  170. Wiebers DO, Wilson DM, McLeod RA et al. Renal stones in Wilson’s disease. Am J Med 1979;67:249–254.

    Article  PubMed  CAS  Google Scholar 

  171. Eriksson P, Denneberg T, Enestrom S et al. Urolithiasis and distal renal tubular acidosis preceding primary Sjögren’s syndrome: a retrospective study 5–53 years after the presentation of urolithiasis. J Int Med 1996;239:483–488.

    Article  CAS  Google Scholar 

  172. Restaino I, Kaplan BS, Stanley C et al. Nephrolithiasis, hypocitraturia, and a distal renal tubular acidification defect in type I glycogen storage disease. J Pediatr 1992;122:392–396.

    Google Scholar 

  173. Chen YT, Coleman RA, Scheinman JI et al. Renal disease in type 1 glycogen storage disease. N Engl J Med 1988;318:7–11.

    Article  PubMed  CAS  Google Scholar 

  174. Weinstein DA, Somers MJG, Wolfsdorf JI. Decreased urinary citrate excretion in type 1a glycogen storage disease. J Pediatr 2001;138:378–382.

    Article  PubMed  CAS  Google Scholar 

  175. Chen YT. Type I glycogen storage disease: kidney involvement, pathogenesis and its treatment. Pediatr Nephrol 1991;5:71–76.

    Article  PubMed  CAS  Google Scholar 

  176. Chang WN, Cheng YF. Nephrolithiasis and nephrocalcinosis in cerebrotendinous xanthomatosis: report of three siblings. Eur Neurol 1995;35:55–57.

    Article  PubMed  CAS  Google Scholar 

  177. Brenner RJ, Spring DB, Sebastian A et al. Incidence of radiologically evident bone disease, nephrocalcinosis, and nephrolithiasis in various types of renal tubular acidosis. N Engl J Med 1982;307:217–221.

    Article  PubMed  CAS  Google Scholar 

  178. Rodriguez-Soriano J, Vallo A. Renal tubular acidosis. Pediatr Nephrol 1990;4:268–275.

    Article  PubMed  CAS  Google Scholar 

  179. Uribarri J, Oh MS, Pak CYC. Renal stone risk factors in patients with type IV renal tubular acidosis. Am J Kidney Dis 1994;23:784–787.

    PubMed  CAS  Google Scholar 

  180. Abate N, Chandalia M, Cabo-Chan AV et al. The metabolic syndrome and uric acid nephrolithiasis: novel features of renal manifestation of insulin resistance. Kidney Int 2004;65:386.

    Article  PubMed  CAS  Google Scholar 

  181. Cameron MA, Baker LA, Maalouf NM et al. Circadian variation in urine ph and uric acid nephrolithiasis risk. Nephrol Dial Transplant 2007;22:2375–2378.

    Article  PubMed  Google Scholar 

  182. Asplin JR, Coe FL. Hyperoxaluria in kidney stone formers treated with modern bariatric surgery. J Urol 2007;177:565–569.

    Article  PubMed  Google Scholar 

  183. Miller NL. Modern bariatric surgery and nephrolithiasis – are we on the verge of a new epidemic? J Urol 2008;179:403–404.

    Article  PubMed  Google Scholar 

  184. Sinha MK, Callazo-Clavell ML, Rule A et al. Hyperoxaluric nephrolithiasis is a complication of Rou-en-Y gastric bypass surgery. Kidney Int 2007;72:100–107.

    Article  PubMed  CAS  Google Scholar 

  185. Osther PJ, Mathiasen H, Hansen AB et al. Urinary acidification and urinary excretion of calcium and citrate in women with bilateral medullary sponge kidney. Urol Int 1994;52:126–130.

    Article  PubMed  CAS  Google Scholar 

  186. Torres VE, Erickson SB, Smith LH et al. The association of nephrolithiasis and autosomal dominant polycystic kidney disease. Am J Kidney Dis 1988;11:318–325.

    PubMed  CAS  Google Scholar 

  187. Levine E, Grantham JJ. Calcified renal stones and cyst calcifications in autosomal dominant polycystic and kidney disease: clinical and CT study in 84 patients. Am J Radiol 1992;159:77–81.

    CAS  Google Scholar 

  188. Praga M, Martinez MA, Andres A et al. Association of thin basement membrane nephropathy with hypercalciuria, hyperuricosuria, and nephrolithiasis. Kidney Int 1998;54:915–920.

    Article  PubMed  CAS  Google Scholar 

  189. Black J, Stapleton FB, Roy S et al. Varied types of urinary calculi in patients with cystinosis without tubular acidosis. Pediatrics 1986;78:295–297.

    PubMed  CAS  Google Scholar 

  190. Saleem MA, Milford DV, Alton H et al. Hypercalciuria and ultrasound abnormalities in children with cystinosis. Pediatr Nephrol 1995;9:45–47.

    Article  PubMed  CAS  Google Scholar 

  191. Van’t Hoff WG, Gretz N. The treatment of cystinosis with cysteamine and phosphocysteamine in the United Kingdom and Eire. Pediatr Nephrol 1995;9:685–689.

    Article  PubMed  Google Scholar 

  192. Fischbach M, Terzic J, Cavalier A et al. Renal stones in nephropathic cystinosis treated with phosphocysteamine. Pediatr Nephrol 1997;11:787–788.

    Article  PubMed  CAS  Google Scholar 

  193. Azizi E, Eshel G, Aladjem M. Hypercalciuria and nephrolithiasis as a presenting sign in Wilson disease. Eur J Pediatr 1989;148:548–549.

    Article  PubMed  CAS  Google Scholar 

  194. Smith LH, Fromm H, Hofmann AF. Acquired hyperoxaluria, nephrolithiasis, and intestinal disease: description of a syndrome. N Engl J Med 1972;286:1371–1375.

    Article  PubMed  CAS  Google Scholar 

  195. Smith LH, Werness PG, McCall JT. (1980) Enteric hyperoxaluria and other hyperoxaluric states. Contemporary Issues in Nephrology, In: Coe FL (guest ed), Brenner BM, Stein JA (eds.). New York, Churchill-Livingstone.

    Google Scholar 

  196. Chidekel AS, Dolan TF. Cystic fibrosis and calcium oxalate nephrolithiasis. Yale J Biol Med 1996;69:317–321.

    PubMed  CAS  Google Scholar 

  197. Bohles H, Beggardt B, Beeg T et al. Antibiotic treatment-induced tubular dysfunction as a risk factor for renal stone formation in cystic fibrosis. J Pediatr 2002;140:103–109.

    Article  PubMed  Google Scholar 

  198. Katz SM, Krueger LJ, Falkner B. Microscopic nephrocalcinosis in cystic fibrosis. N Engl J Med 1988;319:263–266.

    Article  PubMed  CAS  Google Scholar 

  199. Turner MA, Goldwater D, David TJ. Oxalate and calcium excretion in cystic fibrosis. Arch Dis Child 2000;83:244–247.

    Article  PubMed  CAS  Google Scholar 

  200. Jacinto JS, Modanlou HD, Crade M et al. Renal calcification incidence in very low birth weight infants. Pediatr 1988;81:31–35.

    CAS  Google Scholar 

  201. Narendra A, White MP, Rolton HA et al. Nephrocalcinosis in preterm babies. Arch Dis Child Fetal Neonatal Ed 2001;85:F207–F213.

    Article  PubMed  CAS  Google Scholar 

  202. Karlowicz MG, Katz ME, Adelman RD et al. Nephrocalcinosis in very low birth weight neonates: family history of kidney stones and ethnicity as independent risk factors. J Pediatr 1993;122:635–638.

    Article  PubMed  CAS  Google Scholar 

  203. Short A, Cooke RWI. The incidence of renal calcification in preterm infants. Arch Dis Child 1991;66:412–417.

    Article  PubMed  CAS  Google Scholar 

  204. Campfield T, Braden G. Urinary oxalate excretion by very low birth weight infants receiving parenteral nutrition. Pediatrics 1989;84:860–863.

    PubMed  CAS  Google Scholar 

  205. Monge M, Garcia-Nieto VM, Domenech E et al. Study of renal metabolic disturbances related to renal lithiasis at school age in very low birth weight children. Nephron 1998;79:269–273.

    Article  PubMed  CAS  Google Scholar 

  206. Noble CB, Klein LT, Staiman VR et al. Ureteral obstruction secondary to indinavir in the pediatric HIV population. Pediatr Radiol 1998;28:627–629.

    Article  PubMed  CAS  Google Scholar 

  207. Kopp JB, Miller KD, Mican JM et al. Crystalluria and urinary tract abnormalities associated with indinavir. Ann Int Med 1997;127:119–125.

    PubMed  CAS  Google Scholar 

  208. Saltel E, Angel JB, Futter NG et al. Increased prevalence and analysis of risk factors for indinavir nephrolithiasis. J Urol 2000;164:1895–1897.

    Article  PubMed  CAS  Google Scholar 

  209. Gagnon RF, Tecimer SN, Watters AK et al. Prospective study of urinalysis abnormalities in HIV-positive individuals treated with indinavir. Am J Kidney Dis 2000;36:507–515.

    Article  PubMed  CAS  Google Scholar 

  210. Zinn HL, Orentlicher RJ, Haller JO et al. Radiographically occult ureteral calculi in an HIV-positive child undergoing indinavir therapy. Emerg Radiol 2000;7:114–116.

    Article  Google Scholar 

  211. Van Rossum AM, Dieleman JP, Fraaij PL et al. Indinavir-associated asymptomatic nephrolithiasis and renal cortex atrophy in two HIV-1 infected children. AIDS 2001;15:1745–1747.

    Article  PubMed  CAS  Google Scholar 

  212. Cochat P, Cochat N, Jouvenet M et al. Ceftriaxone-associated nephrolithiasis. Nephrol Dial Transplant 5:974–976.

    Google Scholar 

  213. De Moor RA, Egberts ACG, Schroder CH. Ceftriaxone-associated nephrolithiasis and biliary pseudolithiasis. Eur J Pediatr 1999;158:975–977.

    Article  PubMed  CAS  Google Scholar 

  214. Pickens CL, Milliron AR, Russner AL et al. Abuse of guaifenesin-containing medications generates an excess of a carboxylate salt of beta-(2-methoxyphenoxy)-lactic acid, a guaifenesin metabolite, and results in urolithiasis. Urol 1999;54:23–27.

    Article  PubMed  CAS  Google Scholar 

  215. Daudon M, Estepa L. Drug induced lithiases. Presse Medicale 1998;11:675–683.

    Google Scholar 

  216. Ahlstrand C, Tiselius HG. Urine composition and stone formation during treatment with acetazolamide. Scand J Urol Nephrol 1987;21:225–228.

    Article  PubMed  CAS  Google Scholar 

  217. Levisohn PM. Safety and tolerability of topiramate in children. J Child Neurol 2000;15:S22–S26.

    Article  PubMed  Google Scholar 

  218. Kubota M, Nishi-Nagase M, Sakakihara Y et al. Zonisamide-induced urinary lithiasis in patients with intractable epilepsy. Brain Develop 2000;22:230–233.

    Article  CAS  Google Scholar 

  219. Carlsen J, Durcan J, Zabriskie N et al. Nephrolithiasis with dorzolamide. Arch Ophthalm 1999;117:1087–1088.

    Article  CAS  Google Scholar 

  220. Siwinska A, Gluszek J, Maciejewski J et al. Intravenous aminophylline increases the degree of saturation of urine with calcium phosphate and struvite. Int Urol Nephrol 1997;29:141–146.

    Article  PubMed  CAS  Google Scholar 

  221. Singh A, Sarkar SR, Gaber LW et al. Acute oxalate nephropathy associated with orlistat, a gastrointestinal lipase inhibitor. Am J Kidney Dis 2007;49:153–157.

    Article  PubMed  CAS  Google Scholar 

  222. Valaseri A, Van Reen R. Pediatric bladder stone disease: current status of research. J Pediatr 1968;72:546.

    Article  Google Scholar 

  223. Frassetto L, Morris RC, Sellmeyer DE et al. Diet, evolution and aging: the pathophysiologic effects of the post-agricultural inversion of the potassium-to-sodium and base-to-chloride ratios in the human diet. Eur J Nutr 2001;40:200–213.

    Article  PubMed  CAS  Google Scholar 

  224. Taylor EN, Curhan GC. Fructose consumption and the risk of kidney stones. Kidney Int 2008;73:207–212.

    Article  PubMed  CAS  Google Scholar 

  225. Asselman M, Verkoelen CF. Fructase intake as a risk factor for kidney stone disease. Kidney Int 2008;73:139–140.

    Article  PubMed  CAS  Google Scholar 

  226. Reddy ST, Wang CY, Sakhaee K et al. Effect of low-carbohydrate high-protein diets on acid-base balance, stone-forming propensity, and calcium metabolism. Am J Kidney Dis 2002;40:265–274.

    Article  PubMed  CAS  Google Scholar 

  227. Kielb S, Koo HP, Bloom DA, et al. Nephrolithiasis associated with the ketogenic diet. J Urol 2000;164:464–466.

    Article  PubMed  CAS  Google Scholar 

  228. Sampath A, Kossoff EH, Furth SL et al. Kidney stones and the ketogenic diet: risk factors and prevention. J Child Neurol 2007;22:375–378.

    Article  PubMed  Google Scholar 

  229. Groesbeck DK, Bluml RM, Kossoff EH. Long-term use of the ketogenic diet in the treatment of epilepsy. Dev Med Child Neurol 2006;48:978–981.

    Article  PubMed  Google Scholar 

  230. Herzberg GZ, Fivush BA, Kinsman SL et al. Urolithiasis associated with the ketogenic diet. J Pediatr 1990;117:743–745.

    Article  PubMed  CAS  Google Scholar 

  231. Rodman JS. Struvite stones. Nephron 1999;81:50–59.

    Article  PubMed  CAS  Google Scholar 

  232. Michaels EK, Fowler JE. Extracorporeal shock wave lithotripsy for struvite calculi: prospective study with extended follow-up. J Urol 1991;146:728–732.

    PubMed  CAS  Google Scholar 

  233. Segura JW. Staghorn calculi. Urol Clin North Am 1997;24:71–80.

    Article  PubMed  CAS  Google Scholar 

  234. Samuel M, Duffy P, Capps S et al. Xanthogranulomatous pyelonephritis in childhood. J Pediatr Surg 2001;36:598–601.

    Article  PubMed  CAS  Google Scholar 

  235. Bingol-Kologlu M, Ciftci AO, Senocak ME, et al. 2002;Eur J Pediatr Surg 12:42–48.

    Article  PubMed  CAS  Google Scholar 

  236. Schulman H, Barki Y, al HertzanuYet. Diffuse xanthogranulomatous pyelonephritis in childhood. J Clin Ultrasound 25:207–210.

    Google Scholar 

  237. Meria P, Desgrippes A, Fournier R et al. The conservative management of corynebacterium group D2 encrusted pyelitis. Br J Urol Int 1999;84:270–275.

    Article  CAS  Google Scholar 

  238. Nadler RB, Hoffman TA, McClennan BL et al. Corynebacterium urealyticum (CIC, group D2) associated with staghorn calculus: treatment by percutaneous debulking and chemolysis. J Endourol 1996;10:31–34.

    Article  PubMed  CAS  Google Scholar 

  239. Aguado JM, Morales JM, Salto E et al. Encrusted pyelitis and cystitis by corynebacterium urealyticum (CDC group D2): a new and threatening complication following renal transplant. Transplantation 1993;56:617–622.

    Article  PubMed  CAS  Google Scholar 

  240. Morales JM, Aguado JM, Diaz-Gonzalez R et al. Alkaline-encrusted pyelitis/cystitis and urinary tract infection due to corynebacterium urealyticum: a new severe complication after renal transplantation. Transplant Proc 1992;24:81–82.

    PubMed  CAS  Google Scholar 

  241. Soriano F, Ponte C, Santamaria M et al. Struvite crystal formation by Corynebacterium group D2 in human urine and its prevention by acetohydroxamic acid. Eur Urol 1987;13:271–273.

    PubMed  CAS  Google Scholar 

  242. Verbaeys A, Minnaert H, De Paepe M et al. Results of urometabolic evaluation in 127 patients with renal calculus disease. Urology 1985;25:22–25.

    Article  PubMed  CAS  Google Scholar 

  243. Hsu THS, Streem SB. Metabolic abnormalities in patients with caliceal diverticular calculi. J Urol 1998;160:1640–1642.

    Article  PubMed  CAS  Google Scholar 

  244. Husmann DA, Milliner DS, Segura JW. Ureteropelvic junction obstruction with concurrent renal pelvic calculi in the pediatric patient: a long-term followup. J Urol 1995;156:741–743.

    Article  Google Scholar 

  245. Glenn JF. Analysis of 51 patients with horseshoe kidney. N Engl J Med 1959;261:684–687.

    Article  PubMed  CAS  Google Scholar 

  246. Silver RI, Gros DAC, Jeffs RD et al. Urolithiasis in the exstrophy-epispadias complex. J Urol 1997;158:1322–1326.

    Article  PubMed  CAS  Google Scholar 

  247. Mathoera RB, Kok DJ, Nijman RJM. Bladder calculi in augmentation cystoplasty in children. Pediatr Urol 2000;56:482–487.

    Article  CAS  Google Scholar 

  248. Khoury AE, Salomon M, Doche R et al. Stone formation after augmentation cystoplasty: the role of intestinal mucus. J Urol 1997;158:1133–1137.

    Article  PubMed  CAS  Google Scholar 

  249. Shekarriz B, Upadhyay J, Demirbilek S et al. Surgical complications of bladder augmentation: comparison between various enterocystoplasties in 133 patients. Urol 2000;55:123–128.

    Article  PubMed  CAS  Google Scholar 

  250. Wenzl JE, Burke EC, Stickler GB et al. Nephrolithiasis and nephrocalcinosis in children. Pediatr 1968;41:57–61.

    CAS  Google Scholar 

  251. Noe HN. Hypercalciuria and pediatric stone recurrences with and without structural abnormalities. J Urol 2000;164:1094–1096.

    Article  PubMed  CAS  Google Scholar 

  252. DeFoor W, Asplin J, Jackson E et al. Results of prospective trial to compare normal urine supersaturation in children and adults. J Urol 2005;174:1708–1710.

    PubMed  CAS  Google Scholar 

  253. Stapleton FB, Chesney RW, Behrmann AT et al. Increased urinary excretion of renal N-acetyl-β-glucosaminidase in hypercalciuria. Am J Dis Child 1985;139:950–952.

    PubMed  CAS  Google Scholar 

  254. Balla AA, Salah AM, Abdalmotaal E et al. N-acetyl-β-D-glucosaminidase excretion in healthy children and in pediatric patients with urolithiasis. World J Urol 1998;16:413–416.

    Article  PubMed  CAS  Google Scholar 

  255. Bonilla-Felix M, Villegas-Medina O, Vehaskari VM. Renal acidification in children with idiopathic hypercalciuria. J Pediatr 1994;124:529–534.

    Article  PubMed  CAS  Google Scholar 

  256. Hamed IA, Czerwinski AW, Coats B et al. Familial absorptive hypercalciuria and renal tubular acidosis. Am J Med 1979;67:385–391.

    Article  PubMed  CAS  Google Scholar 

  257. Backman U, Danielson BG, Johansson G et al. Incidence and clinical importance of renal tubular defects in recurrent renal stone formers. Nephron 1980;25:96–101.

    Article  PubMed  CAS  Google Scholar 

  258. Gambaro G, Favaro S, D’Angelo A. Risk for renal failure in nephrolithiasis. Am J Kidney Dis 2001;37:233–243.

    Article  PubMed  CAS  Google Scholar 

  259. Lindell A, Denneberg T, Granerus G. Studies on renal function in patients with cystinuria. Nephron 1997;77:76–85.

    Article  PubMed  CAS  Google Scholar 

  260. Worcester EM, Parks JH, Evan AP et al. Renal function in patients with nephrolithiasis. J Urol 2006;176:600.

    Article  PubMed  Google Scholar 

  261. Worcester EM, Coe FL, Evan AP et al. Reduced renal functio and benefits of treatment in cystinuria vs other forms of nephrolithiasis. BJU Int 2006;97:1285.

    Article  PubMed  CAS  Google Scholar 

  262. Moore ES, Coe FL, McMann BJ et al. Idiopathic hypercalciuria in children: prevalence and metabolic characteristics. J Pediatr 1978; 92:906–910.

    Google Scholar 

  263. Barratt TM, Kasidas GP, Murdoch I et al. Urinary oxalate and glycolate excretion and plasma oxalate concentration. Arch Dis Child 1991;66:501–503.

    Google Scholar 

  264. Norman ME, Feldman NI, Cohn RM et al. Urinary citrate excretion in the diagnosis of distal renal tubular acidosis. J Pediatr 1978; 92:394–400.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Milliner, D.S. (2009). Urolithiasis. In: Avner, E., Harmon, W., Niaudet, P., Yoshikawa, N. (eds) Pediatric Nephrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-76341-3_58

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-76341-3_58

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-76327-7

  • Online ISBN: 978-3-540-76341-3

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics