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Low-Cost Microdevices for Point-of-Care Testing

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Point-of-Care Diagnostics on a Chip

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

Abstract

Microdevices enable clinical diagnostics to be miniaturized for use at the point-of-care (POC). Microdevices can be composed of microfilters, microchannels, microarrays, micropumps, microvalves, and microelectronics, and these mechanical and electrical components can be integrated onto chips to analyze and control biological objects at the microscale. The miniaturization of diagnostic tests offers many advantages over centralized laboratory testing, such as small reagent volumes, rapid analysis, small size, low power consumption, parallel analysis, and functional integration of multiple devices. Here, we review work on the development of microdevices to diagnose disease at POC settings.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, 1210 Amsterdam Avenue, New York, NY, 10027, USA

    Curtis D. Chin, Sau Yin Chin, Tassaneewan Laksanasopin & Samuel K. Sia

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  1. Curtis D. Chin
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  2. Sau Yin Chin
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  3. Tassaneewan Laksanasopin
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  4. Samuel K. Sia
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Correspondence to Samuel K. Sia .

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  1. , Department of Bioengineering, University of Pennsylvania, 210 South 33rd Street, Philadelphia, 19104-6321, Pennsylvania, USA

    David Issadore

  2. , School of Engineering, Applied Sciences, Harvard University, Oxford Street 29, Cambridge, 02138, Massachusetts, USA

    Robert M. Westervelt

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Chin, C.D., Chin, S.Y., Laksanasopin, T., Sia, S.K. (2013). Low-Cost Microdevices for Point-of-Care Testing. In: Issadore, D., Westervelt, R. (eds) Point-of-Care Diagnostics on a Chip. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29268-2_1

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