Abstract
This paper is devoted to the analysis and the extraction of information from bio-medical images. The proposed technique is based on object and contour detection, curve evolution and segmentation. We present a particular active contour model for 2D and 3D images, formulated using the level set method, and based on a 2-phase piecewise-constant segmentation. We then show how this model can be generalized to segmentation of images with more than two segments. The techniques used are based on the Mumford-Shah [21] model. By the proposed models, we can extract in addition measurements of the detected objects, such as average intensity, perimeter, area, or volume. Such informations are useful when in particular a time evolution of the subject is known, or when we need to make comparisons between different subjects, for instance between a normal subject and an abnormal one. Finally, all these will give more informations about the dynamic of a disease, or about how the human body growths. We illustrate the efficiency of the proposed models by calculations on two-dimensional and three-dimensional bio-medical images.
This work was supported in part by ONR Contract N00014-96-1-0277 and NSF Contract DMS-9973341.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ambrosio, L., Tortorelli, V.M.: Approximation of functionals depending on jumps by elliptic functionals via Γ-convergence. Comm. Pure Appl. Math. 43 (1990) 999–1036.
Ambrosio, L., Tortorelli, V.M.: On the Approximation of Free Discontinuity Problems. Bolletino U.M.I. (7)6-B (1992) 105–123.
Caselles, V., Catté, F., Coll, T., Dibos, F.: A geometric model for active contours in image processing. Numerische Mathematik 66 (1993) 1–31.
Caselles, V., Kimmel, R., Sapiro, G.: On geodesic active contours. Int. J. of Computer Vision 22/1 (1997) 61–79.
Chambolle, A.: Image segmentation by variational methods: Mumford and Shah functional and the discrete approximations. SIAM J. Appl. Math. 55(3) (1995) 827–863.
Chambolle, A.: Finite-differences discretizations of the Mumford-Shah functional. M2AN Math. Model. Numer. Anal. 33(2) (1999) 261–288.
Chan, T., Vese, L.: Active contours without edges. IEEE Transactions on Image Processing. 10/2 (2001) 266–277.
Chan, T., Vese, L.: Image segmentation using level sets and the piecewiseconstant Mumford-Shah model. UCLA CAM Report 00-14 (2000).
Kass, M., Witkin, A., Terzopoulos, D.: Snakes: Active contour models. Int. J. of Computer Vision 1 (1988) 321–331.
Kichenassamy, S., Kumar, A., Olver, P., Tannenbaum, A., Yezzi, A.: Gradient flows and geometric active contour models. Proceedings of ICCV, Cambridge, (1995) 810–815.
Kimmel, R., Malladi, R., Sochen, N.: Images as Embedded Maps and Minimal Surfaces: Movies, Color, Texture, and Volumetric Medical Images. International Journal of Computer Vision, 39/2 (2000) 111–129.
Koepfler, G., Lopez, C., Morel, J.M.: A multiscale algorithm for image segmentation by variational method. SIAM Journal of Numerical Analysis 31-1 (1994) 282–299.
Malladi, R., Kimmel, R., Adalsteinsson, D., Caselles, V., Sapiro, G., Sethian, J.A.: A Geometric Approach to Segmentation and Analysis of 3D Medical Images. Proc. of IEEE/SIAM Workshop on Biomedical Image Analysis, San-Francisco, California, (1996).
Malladi, R., Sethian, J.A.: A Real-Time Algorithm for Medical Shape Recovery. Proc. of International Conf. on Computer Vision. Mumbai, India (1998) 304–310.
Malladi, R., Sethian, J.A.: Level Set Methods for Curvature Flow, Image Enhancement, and Shape Recovery in Medical Images. Visualization and Mathematics, Eds. H. C. Hege, K. Polthier, Springer Verlag, Heidelberg (1997) 329–345.
Malladi, R., Sethian, J.A., Vemuri, B.C.: A Topology Independent Shape Modeling Scheme. Proc. SPIE Conf. on Geometric Methods in Computer Vision II 2031 (1993) 246–258, San Diego.
Malladi, R., Sethian, J.A., Vemuri, B.C.: Evolutionary Fronts for TopologyIndependent Shape Modeling and Recovery. Proc. of the Third European Conference on Computer Vision, LNCS 800 (1994) 3–13, Stockholm, Sweden.
Malladi, R., Sethian, J.A., Vemuri, B.C.: Shape Modeling with Front Propagation: A Level Set Approach. IEEE Transactions on Pattern Analysis and Machine Intelligence. 17/2 (1995) 158–175.
March, R.: Visual Reconstruction with discontinuities using variational methods. Image and Vision Computing 10 (1992) 30–38.
Morel J.M., Solimini, S.: Variational Methods in Image Segmentation. Birkhäuser, PNLDE 14 (1994).
Mumford, D., Shah, J.: Optimal approximation by piecewise smooth functions and associated variational problems. Comm. Pure Appl. Math. 42 (1989) 577–685.
Osher, S., Sethian, J.A.: Fronts Propagating with Curvature-Dependent Speed: Algorithms Based on Hamilton-Jacobi Formulation. Journal of Computational Physics 79 (1988) 12–49.
Samson, C., Blanc-Féraud, L., Aubert, G., Zerubia, J.: A Level Set Model for Image Classification. M. Nilsen et al. (Eds.): Scale-Space’99, LNCS 1682 (1999) 306–317, Springer-Verlag Berlin Heidelberg.
Sapiro, G., Kimmel, R., Caselles, V.: Measurements in medical images via geodesic deformable contours. Proc. SPIE-Vision Geometry IV, Vol. 2573 (1995), San Diego, California.
Shah, J.: A Common Framework for Curve Evolution, Segmentation and Anisotropic Diffusion. IEEE Conference on Computer Vision and Pattern Recognition (1996).
Shah, J.: Riemannian Drums, Anisotropic Curve Evolution and Segmentation. M. Nilsen et al. (Eds.): Scale-Space’99, LNCS 1682 (1999) 129–140, Springer-Verlag Berlin Heidelberg.
Yezzi, A. Jr., Kichenassamy, S., Kumar, A., Olver, P., Tannenbaum, A.: A Geometric Snake Model for Segmentation of Medical Imagery. IEEE Transactions on Medical Imaging. 16/2 (1997) 199–209.
Yezzi, A., Tsai, A., Willsky, A.: A statistical approach to snakes for bimodal and trimodal imagery. Int. Conf. on Computer Vision (1999).
Zhao, H.-K., Chan, T., Merriman, B., Osher, S.: A Variational Level Set Approach to Multiphase Motion. J. Comput. Phys. 127 (1996) 179–195.
Zhu, S.C., Lee, T.S., Yuille, A.L.: Region competition: Unifying snakes, region growing, energy/Bayes/MDL for multi-band image segmentation. Proceedings of the IEEE 5th ICCV, Cambridge (1995) 416–423.
Zhu, S.C., Yuille, A.L.: Region competition: Unifying snakes, region growing, and Bayes/MDL for multi-band image segmentation. IEEE Transactions on Pattern Analysis and Machine Intelligence 18 (1996) 884–900.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2002 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Chan, T.F., Vese, L.A. (2002). Active Contour and Segmentation Models using Geometric PDE’s for Medical Imaging. In: Malladi, R. (eds) Geometric Methods in Bio-Medical Image Processing. Mathematics and Visualization. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55987-7_4
Download citation
DOI: https://doi.org/10.1007/978-3-642-55987-7_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-62784-2
Online ISBN: 978-3-642-55987-7
eBook Packages: Springer Book Archive