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Preoperative (Neoadjuvant) Chemotherapy for Breast Cancer: Outline of the British Columbia Trial

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Preoperative (Neoadjuvant) Chemotherapy

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 103))

Abstract

The results of the major adjuvant chemotherapy trials show a positive impact of this treatment on the natural history of breast cancer (Jones and Salmon 1984) and, therefore, despite some contrary opinions, adjuvant therapy will likely remain the main form of systemic therapy for newly diagnosed high-risk patients. The number of failure cases after the therapy with conventional adjuvant therapy is, however, still high. In the absence of new curative agents for breast cancer, improvement of scheduling and manipulation of old drugs is the only option left for clinicians to improve survival. Neoadjuvant (preoperative) chemotherapy is an example of such manipulation and its application in the management of breast cancer will be a part of this discussion.

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Author information

Authors and Affiliations

  1. Cancer Control Agency of British Columbia, 600 West 10th Avenue, Vancouver, B.C., V5Z 4E6, Canada

    J. Ragaz

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  1. J. Ragaz
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Editors and Affiliations

  1. Cancer Control Agency of British Columbia, 600 West 10th Avenue, Vancouver, B.C., V5Z 4E6, Canada

    Joseph Ragaz M. D. , Pierre R. Band M. D.  & James H. Goldie M.D. ,  & 

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© 1986 Springer-Verlag Berlin Heidelberg

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Ragaz, J. (1986). Preoperative (Neoadjuvant) Chemotherapy for Breast Cancer: Outline of the British Columbia Trial. In: Ragaz, J., Band, P.R., Goldie, J.H. (eds) Preoperative (Neoadjuvant) Chemotherapy. Recent Results in Cancer Research, vol 103. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82671-9_9

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  • DOI: https://doi.org/10.1007/978-3-642-82671-9_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-82673-3

  • Online ISBN: 978-3-642-82671-9

  • eBook Packages: Springer Book Archive

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