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Glutamate in the Immune System: Glutamate Receptors in Immune Cells, Potent Effects, Endogenous Production and Involvement in Disease

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Nerve-Driven Immunity

Abstract

Glutamate, an amino acid, is the principal excitatory neurotransmitter within the vertebrate nervous system. Glutamate is involved in most aspects of normal brain function including cognition, memory and learning, and also plays major roles in the development of the central nervous system, including synapse induction and elimination, and cell migration, differentiation and death. Glutamate further plays a signaling role in peripheral organs and tissues, such as the heart, kidney, intestine, lungs, muscles, liver, ovary, testis, bone, pancreas and the adrenal, pituitary and pineal glands.

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Authors and Affiliations

  1. Department of Cell Biology and Host-Pathogen Interactions, Cochin Institute, CNRS (UMR 8104), INSERM U1016, Paris Descartes University, Paris, France

    Yonatan Ganor

  2. The School of Behavioral Sciences, The Academic College of Tel-Aviv-Yaffo, Tel Aviv, Israel

    Mia Levite

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  1. Yonatan Ganor
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  2. Mia Levite
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Correspondence to Yonatan Ganor .

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  1. School of Behavioral Sciences, The Academic College of TLV Yaffo, Rabenu Yeruham Street 29, Yaffo, 61083, Israel

    Mia Levite

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Ganor, Y., Levite, M. (2012). Glutamate in the Immune System: Glutamate Receptors in Immune Cells, Potent Effects, Endogenous Production and Involvement in Disease. In: Levite, M. (eds) Nerve-Driven Immunity. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0888-8_4

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