Abstract
A case is presented of an intraocular T-cell lymphoma mimicking a ring melanoma of the iris and being the first manifestation of systemic disease. A 51-year-old woman was referred with an anterior uveitis, initially presenting as a granulomatous iritis. Nodules had developed in the circumference and the lesion now imitated a malignant melanoma of the iris, which was also the diagnosis from a biopsy specimen with routine staining. Clinical, haematological and serologcial examination revealed no other symptoms or signs. Lymphocytic markers applied to the biopsy specimen and to the enucleated eye revealed a highly malignant T-cell lymphoma infiltrating the iris, ciliary body, anterior choroid, retina and the adjacent vitreous body. Further examination later showed T-cell lymphoma in the bone marrow, the only other organ involved. The patient died in a leukaemic phase about 1 year after the first admission. Previous cases of T-cell lymphoma with ocular involvement are reviewed.
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Jensen, O.A., Johansen, S. & Kiss, K. Intraocular T-cell lymphoma mimicking a ring melanoma. First manifestation of systemic disease. Graefe's Arch Clin Exp Ophthalmol 232, 148–152 (1994). https://doi.org/10.1007/BF00176784
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DOI: https://doi.org/10.1007/BF00176784