Summary
The cortical projection areas of thalamic neurons with basal ganglia and/or cerebellar inputs were studied electrophysiologically in unanesthetized monkeys. Thalamic neurons which receive inhibition from the pallidum were found to project to the motor cortex (area 4) as well as to premotor cortex. The neurons with pallidal input and motor cortical projection were located mainly in VLo. This result indicates that the basal ganglia innervate the motor cortex through the thalamus. Thus the basal ganglia can modify the cortical output for controlling movements directly through this pathway as compared with its influence through the prefrontal and premotor cortices.
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References
Asanuma C, Thach WT, Jones EG (1983) Distribution of cerebellar terminations and their relation to other afferent terminations in the ventral lateral thalamic region of the monkey. Brain Res Rev 5: 237–265
DeVito JL, Anderson ME (1982) An autoradiographic study of efferent connections of the globus pallidus in Macaca mulatta. Exp Brain Res 46: 107–117
Kalil K (1981) Projections of the cerebellar and dorsal column nuclei upon the thalamus of the rhesus monkey. J Comp Neurol 195: 25–50
Kemp JM, Powell TPS (1971) The connexions of the striatum and globus pallidus: synthesis and speculation. Philos Trans R Soc Lond B 262: 441–457
Kievit J, Kuypers HGJM (1977) Organization of the thalamocortical connexions to the frontal lobe in the rhesus monkey. Exp Brain Res 29: 299–322
Kim R, Nakano K, Jayaraman A, Carpenter MB (1976) Projections of the globus pallidus and adjacent structures: an autoradiographic study in the monkey. J Comp Neurol 169: 263–290
Kuo J-S, Carpenter MB (1973) Organization of pallidothalamic projections in the rhesus monkey. J Comp Neurol 151: 201–236
Miyata M, Sasaki K (1983) HRP studies on thalamocortical neurons related to the cerebellocerebral projection in the monkey. Brain Res 274: 213–224
Olszewski J (1952) The thalamus of the Macaca mulatta, an atlas for use with the stereotaxic instrument. S Karger, Basel New York
Schell GR, Strick PL (1984) The origin of thalamic inputs to the arcuate premotor and supplementary motor areas. J Neurosci 4: 539–560
Stanton GB (1980) Topographical organization of ascending cerebellar projections from the dentate and interposed nuclei in Macaca mulatta: an anterograde degeneration study. J Comp Neurol 190: 699–731
Strick PL (1976) Anatomical analysis of ventrolateral thalamic input to primate motor cortex. J Neurophysiol 39: 1020–1031
Uno M, Ozawa N, Yoshida M (1978) The mode of pallidothalamic transmission investigated with intracellular recording from cat thalamus. Exp Brain Res 33: 493–507
Uno M, Yoshida M, Hirota I (1970) The mode of cerebellothalamic relay transmission investigated with intracellular recording from cells of the ventrolateral nucleus of cat's thalamus. Exp Brain Res 10: 121–139
Yamamoto T, Hassler R, Huber C, Wagner A, Sasaki K (1983) Electrophysiological studies on the pallidoand cerebellothalamic projections in squirrel monkeys (Saimiri sciureus). Exp Brain Res 51: 77–87
Yamamoto T, Noda T, Miyata M, Nishimura Y (1984) Electrophysiological and morphological studies on thalamic neurons receiving entopedunculoand cerebello-thalamic projections in the cat. Brain Res 301: 231–242
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Nambu, A., Yoshida, S. & Jinnai, K. Projection on the motor cortex of thalamic neurons with pallidal input in the monkey. Exp Brain Res 71, 658–662 (1988). https://doi.org/10.1007/BF00248759
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DOI: https://doi.org/10.1007/BF00248759