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Treatment of bone cysts with methylprednisolone acetate

A 9 to 11 year follow-up

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Summary

The long-term results are reported of the treatment of bone cysts by means of the injection of methylprednisolone acetate (MPA) into the bony cavity using Scaglietti's technique.

Eighteen patients were reviewed at a follow-up of 9–11 years from the beginning of the treatment. The results confirm the value of this technique and show a high percentage of recovery.

During the growth period, a recurrence of osteolytic activity in the lesion may be observed after complete healing, though this does not happen frequently. In these cases further prompt treatment with MPA injected into the small osteolytic areas brings about their complete resolution.

These observations lead us to conclude that a bone cyst can never be considered completely healed before complete skeletal maturity is reached. Regular radiological reviews must be carried out in order to recognise and treat promptly the first signs of a recurrence of cystic activity.

Résumé

Les auteurs rapportent les résultats à long terme du traitement des kystes osseux solitaires par injection endo-cavitaire d'acétate de methylprednisolone (technique de Scaglietti).

18 patients ont été revus avec un recul de 9 à 11 ans après le début du traitement. Les résultats observés confirment la validité de cette technique en montrant un haut pourcentage de guérisons.

Dans quelques cas, en cours de croissance, on a pu observer la reprise de l'activité ostéolytique après la guérison complète d'une lésion. Dans ces cas, la reprise rapide du traitement par l'acétate de methylprednisolone centré sur les nouvelles petites aires d'ostéolyse obtient la guérison.

Ces observations portent les auteurs à penser qu'on ne peut jamais considérer comme complète et définitive la guérison d'un kyste osseux, quelques années après son traitement si la croissance du squelette n'est pas encore terminée. Un contrôle radiographique périodique est donc nécessaire pour reconnaître et traiter dès ses premiers signes une reprise de l'activité ostéolytique.

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de Palma, L., Santucci, A. Treatment of bone cysts with methylprednisolone acetate. International Orthopaedics 11, 23–28 (1987). https://doi.org/10.1007/BF00266054

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