Summary
The long-term results are reported of the treatment of bone cysts by means of the injection of methylprednisolone acetate (MPA) into the bony cavity using Scaglietti's technique.
Eighteen patients were reviewed at a follow-up of 9–11 years from the beginning of the treatment. The results confirm the value of this technique and show a high percentage of recovery.
During the growth period, a recurrence of osteolytic activity in the lesion may be observed after complete healing, though this does not happen frequently. In these cases further prompt treatment with MPA injected into the small osteolytic areas brings about their complete resolution.
These observations lead us to conclude that a bone cyst can never be considered completely healed before complete skeletal maturity is reached. Regular radiological reviews must be carried out in order to recognise and treat promptly the first signs of a recurrence of cystic activity.
Résumé
Les auteurs rapportent les résultats à long terme du traitement des kystes osseux solitaires par injection endo-cavitaire d'acétate de methylprednisolone (technique de Scaglietti).
18 patients ont été revus avec un recul de 9 à 11 ans après le début du traitement. Les résultats observés confirment la validité de cette technique en montrant un haut pourcentage de guérisons.
Dans quelques cas, en cours de croissance, on a pu observer la reprise de l'activité ostéolytique après la guérison complète d'une lésion. Dans ces cas, la reprise rapide du traitement par l'acétate de methylprednisolone centré sur les nouvelles petites aires d'ostéolyse obtient la guérison.
Ces observations portent les auteurs à penser qu'on ne peut jamais considérer comme complète et définitive la guérison d'un kyste osseux, quelques années après son traitement si la croissance du squelette n'est pas encore terminée. Un contrôle radiographique périodique est donc nécessaire pour reconnaître et traiter dès ses premiers signes une reprise de l'activité ostéolytique.
Similar content being viewed by others
References
Allegra F (1978) Dispositivo “ago-vite” per il trattamento locale delle cisti ossee con metil-prednisolone acetato. Arch Putti Chir Organi Mov 29: 405–407
Bartolozzi P (1976) Su 2 aghi-cannula per il trattamento topico di lesioni scheletriche. Arch Putti Chir Organi Mov 27: 251–254
Bocchi L, Orso CA, Bianchini C, Mazzarella F (1982) Cisti ossea e suo trattamento con corticosteroidi. Risultati a distanza. Arch Putti Chir Organi Mov 68: 763–770
Campanacci M, de Sessa L, Bellando Randone P (1975) Cisti ossea (Revisione di 275 osservazioni. Risultati della cura chirurgica e primi risultati delle cura incruenta con metilprednisolone acetato). Arch Putti Chir Organi Mov 62: 471–490
Campanacci M, de Sessa L, Trentani C (1977) Cura incruenta della cisti ossea con iniezioni locali di metilprednisolone acetato secondo Scaglietti. Ital J Orthop Traumatol 3: 27–36
Croce F, Cuccurullo GDG, Passaretti U, Sadile F (1981) Ulteriore esperienza sulla terapia della cisti ossea giovanile con triamcinolone acetonide. Arch Putti Chir Organi Mov 31: 18–25
de Palma L (1978) L'impiego dell'acetato di metilprednisolone nel trattamento delle cisti ossee solitarie. Arch Putti Chir Organi Mov 29: 341–351
Di Pisa A, Ingrosso G, Parenti G (1983) Revisione ed aggiornamento sulla terapia della cisti ossea nell'età evoluziva. Arch Orthop Reumatol 96: 81–88
Grilli FP, Niccoli C (1979) Trattamento della cisti ossea solitaria con metilprednisolone acetato endocavitario. Minerva Med 70: 1463–1466
Gualtieri I, Gualtierei G, Montefusco E (1976) Risultati ottenuti nel trattamento delle cisti ossee mediante infiltrazione con acetato di metilprednisolone. Osp Ital Chir 29: 155
Scaglietti O (1974) Sull'azioe osteogenica dell'acetato di prednisolone. Bol Soc Tosco-Umbra Chir 35: 11–22
Scaglietti O (1974) L'azione osteogenetica dell'acetato di metilprednisolone. Boll Sci Med Bologna 146: 159–160
Scaglietti O, Marchetti PG, Bartolozzi P (1976) Sull' azione topica dei corticosteroidi in microcristalli in alcune lesioni dello scheletro. Arch Putti Chir Organi Mov 27: 9–32
Scaglietti O, Marchetti PG, Bartolozzi P (1978) Risultati a distanza dell'azione topica dell'acetato di metilprednisolone in microcristalli in alcune lesioni dello scheletro. Arch Putti Chir Organi Mov 29: 11–28
Scaglietti O, Marchetti PG, Bartolozzi P (1979) The effects of methylprednisolone acetate in the treatment of bone cysts. J Bone Joint Surg [Br] 61: 200–204
Scaglietti O, Marchetti PG, Bartolozzi P (1982) Final result obtained in the treatment of bone cysts with methylprednisolone acetate (Depo-Medrol) and a discussion of results achieved in other bone lesions. Clin Orthop 165: 33–42
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
de Palma, L., Santucci, A. Treatment of bone cysts with methylprednisolone acetate. International Orthopaedics 11, 23–28 (1987). https://doi.org/10.1007/BF00266054
Issue Date:
DOI: https://doi.org/10.1007/BF00266054