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Cronkhite-canada syndrome associated with colon cancer: Report of a case

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Abstract

A 68-year-old man with the clinical features of Cronkhite-Canada syndrome developed cancer of the ascending colon. Although Cronkhite-Canada syndrome has always been considered a benign condition, it may be a premalignant disorder, as suggested by the clinical course of the patient whose case is described herein.

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References

  1. Cronkhite LW, Canada WJ (1955) Generalized gastrointestinal polyposis. An unusual syndrome of polyposis, pigmentation, alopecia, and onychotrophia. N Engl J Med 252:1011–1015

    Google Scholar 

  2. Shibuya C (1972) An autopsy case of Cronkhite-Canada's syndrome. Generalized gastrointestinal polyposis, pigmentation, alopecia, and onychotrophia. Acta Pathol Jpn 22:171–183

    Google Scholar 

  3. Manousos O, Webster CU (1966) Diffuse gastrointestinal polyposis with ectodermal changes. Gut 7:375–379

    Google Scholar 

  4. Diner WC (1972) The Cronkhite-Canada syndrome. Radiology 105:715–716

    Google Scholar 

  5. Jarnum S, Jensen H (1966) Diffuse gastrointestinal polyposis with ectodermal changes. A case with severe malabsorption and enteric loss of plasma protein and electrolytes. Gastroenterology 50:107–118

    Google Scholar 

  6. Kindblom LG, Angervall L, Santesson B, Selander S (1977) Cronkhite-Canada syndrome. Case report. Cancer 39:2667–2673

    Google Scholar 

  7. Nonomura A, Ohta G, Ibata T, Shinozaki K, Nishino T (1980) Cronkhite-Canada syndrome associated with sigmoid cancer. Acta Pathol Jpn 30:825–845

    Google Scholar 

  8. Da Cruz GMG (1976) Generalized gastrointestinal polyposis. Am J Gastroenterol 47:504–510

    Google Scholar 

  9. Burnell RH (1976) Cronkhite-Canada syndrome. Med J Aust 1:347–348

    Google Scholar 

  10. Rappaport LB, Sperling HV, Stavrides AJ (1986) Colon cancer in the Cronkhite-Canada syndrome. J Clin Gastroenterol 8:199–202

    Google Scholar 

  11. Katayama Y, Kimura M, Konn M (1985) Cronkhite-Canada syndrome associated with a rectal cancer and adenomatous changes in colonic polyposis. Am J Surg Pathol 9:65–71

    Google Scholar 

  12. Daniel ES, Ludwig SL, Lewin KJ, Ruprecht RM, Rajacich GM, Schwabe AR (1982) The Cronkhite-Canada syndrome. An analysis of clinical and pathologic features and therapy in 55 patients. Medicine 61:293–309

    Google Scholar 

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Murai, N., Fukuzaki, T., Nakamura, T. et al. Cronkhite-canada syndrome associated with colon cancer: Report of a case. Surg Today 23, 825–829 (1993). https://doi.org/10.1007/BF00311628

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  • DOI: https://doi.org/10.1007/BF00311628

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