Summary
Seventy-five patients with neurological symptoms of Lyme borreliosis were randomly assigned to intravenous treatment with either penicillin G or doxycycline. After 12 months the treatments were equally effective regarding the clinical picture and laboratory findings. No patient was considered to be a treatment failure. However, one-third of the patients showed delayed recovery, particularly after a longer primary disease duration. A slow recovery, lasting years, was typical of subacute or chronic borreliosis.
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Kohlhepp, W., Oschmann, P. & Mertens, HG. Treatment of Lyme borreliosis. J Neurol 236, 464–469 (1989). https://doi.org/10.1007/BF00328508
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DOI: https://doi.org/10.1007/BF00328508