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Radiologic study of 42 cases of Wilson disease

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Abstract

This paper reports 42 cases of bone and joint radiographic changes in hepatolenticular degeneration. The cases were proven clinically by opthalmologic and laboratory study, and their radiographic and joint changes were divided into five groups: no abnormal findings, osteoporosis, osteomalacia (rickets), distinct changes, and miscellaneous. Distinct changes include marginal bone fragments, angulation of carpal bones, squaring of metacarpal heads, and calcification of the joint capsule or tendon insertion. The mechanism causing the bone changes in hepatolenticular degeneration is also discussed.

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Authors and Affiliations

  1. Department of Radiology, Capital Hospital, Chinese Academy of Medical Sciences, Beijing, Peoples Republic of China

    Xie Yu-zhang M.D. & Zhang Xue-zhe M.D.

  2. Department of Neurology, Capital Hospital, Chinese Academy of Medical Sciences, Beijing, Peoples Republic of China

    Xu Xian-hao M.D., Zhang Zhen-xin M.D. & Feng Ying-kun M.D.

Authors
  1. Xie Yu-zhang M.D.
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  2. Zhang Xue-zhe M.D.
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  3. Xu Xian-hao M.D.
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  4. Zhang Zhen-xin M.D.
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  5. Feng Ying-kun M.D.
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Yu-zhang, X., Xue-zhe, Z., Xian-hao, X. et al. Radiologic study of 42 cases of Wilson disease. Skeletal Radiol 13, 114–119 (1985). https://doi.org/10.1007/BF00352081

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