Summary
Biopsy specimens were taken from parts of earlier fractured bones in seven patients with post-traumatic osteopenia and one healthy volunteer, who were all administered a double dose of tetracycline for the purpose of prelabelling. In the volunteer, specimens were taken from both the proximal tibia epiphysis and the iliac crest. The fraction of labelled surfaces and the rate of apposition were calculated. The results were also compared with normative data from the iliac crest. At least in the first year after fracture, post-traumatic osteopenia appears to be a condition with an increased appositional activity.
Zusammenfassung
Biopsien von Teilen früher frakturierter Knochen wurden entnommen bei sieben Fällen mit posttraumatischer Osteopenie und bei einem gesunden Freiwilligen, die alle mit einer doppelten Dosis Tetracyklin vorbereitet wurden. Von dem Freiwilligen nahm man eine Biopsie vom proximalen Teil der Tibiaepiphyse and von der Crista iliaca. Die Größe der gekennzeichneten Oberflächen und die Appositionsgeschwindigkeit wurde berechnet. Das Resultat wurde auch mit normalen Daten der Crista iliaca verglichen. Es scheint, als ob sich eine post-traumatische Osteopenie, wenigstens im ersten Jahr nach der Fraktur, in einem Zustand gesteigerter Appositionsaktivität befindet.
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Financial support was obtained from the Swedish Medical Research Council (project no. B 83-17X-02737-15)
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Obrant, K.J. Tetracycline double-labelling in post-traumatic osteopenia in man. Arch. Orth. Traum. Surg. 103, 81–82 (1984). https://doi.org/10.1007/BF00389576
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DOI: https://doi.org/10.1007/BF00389576