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Quality of life in survivors of Hodgkin's disease

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Abstract

The great majority of patients with Hodgkin's disease (HD) are successfully treated. However, several reports on treatment sequela have been published. The object of this study was to examine the quality of life (QOL) among survivors of HD focusing on gender and treatment modalities. All patients treated for HD at our oncological unit between 1985 and 1993 (n=55) were registered. In December 1994, 49 survivors were mailed a questionnaire consisting of the EORTC QLQ-C30. Forty-two patients responded (86%). They reported a low frequency of symptoms and a high level of functioning. There was a significant correlation between mantle field irradiation and dyspnoea (p=0.023). Females reported a significantly superior global quality of life (p=0.016) and a lower fatigue score (p=0.040) compared to males. Almost half of the patients reported financial difficulties. To improve QOL among survivors of HD, groups at risk have to be identified. Patients treated with mantle field irradiation and males seems to be at a higher risk. Should the treatment of HD be altered towards less radiotherapy and more chemotherapy?

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References

  1. Cella DF, Pratt A, Holland JC. Persistent anticipatory nausea, vomiting and anxiety in cured Hodgkin's disease patients after completion of chemotherapy. Am J Psychiatry 1986; 143: 641–643.

    Google Scholar 

  2. Gotay CC. Quality of life among survivors of childhood cancer. A critical review and implications for intervention. J Psychosocial Oncol 1987; 5: 5–23.

    Google Scholar 

  3. Yellen SB, Cella DF, Bonomi A. Quality of life in people with Hodgkin's disease. Oncology 1993; 7: 41–45.

    Google Scholar 

  4. Fobair P, Hoppe RT, Bloom J, Cox R, Varghese A, Spiegel D. Psychosocial problems among survivors of Hodgkin's disease. J Clin Oncol 1986; 4: 805–914.

    Google Scholar 

  5. Cella DF, Tross S. Psychological adjustment to survival from Hodgkin's disease. J Consult Clin Psychol 1986; 54: 616–622.

    Google Scholar 

  6. Aaronson NK, Ahmedzai S, Bergman B, et al. for the European Organization for Research and Treatment of Cancer Study Group on Quality of Life. The European Organization for Research and Treatment of Cancer QLQ-C30. A quality of life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993; 85: 365–376.

    Google Scholar 

  7. Norum J, Wist E. Treatment of Hodgkin's disease in a small oncological unit. Eur J Haematol 1993; 50: 297–298.

    Google Scholar 

  8. Norum J, Bremnes RM, Wist E. The ChlVPP regimen, a risk factor for herpes zoster virus infection in patients treated for Hodgkin's disease. Eur J Haematol 1994; 53: 51–53.

    Google Scholar 

  9. Olweny CLM, Juttner CA, Rofe P, et al. Long term effects of cancer treatment and consequences of cure. Cancer survivors enjoy quality of life similar to their neighbours. Eur J Cancer 1993; 29: 826–830.

    Google Scholar 

  10. Wassermann AL, Thompson EI, Williams JA, Fairclough DL. The psychological status of survivors of childhood/ adolescent Hodgkin's disease. Am J Dis Child 1987; 141: 626–631.

    Google Scholar 

  11. Teta MJ, Del Po MC, Kasl SV, Meigs JW, Myers MH, Mulvihill JJ. Psychosocial consequences of childhood and adolescent cancer survival. J Chronic Dis 1986; 9: 751–759.

    Google Scholar 

  12. Norum J, Wist E. Psychological distress in survivors of Hodgkin's disease. Support Care Cancer 1996; 4: (in press).

  13. Bloom JR, Fobair P, Gritz E, et al. Psychosocial outcomes of cancer. A comparative analysis of Hodgkin's disease and testicular cancer. J Clin Oncol 1993; 11: 979–988.

    Google Scholar 

  14. Cella D. Psychosocial adjustments over time to the successful treatment of early versus late stage Hodgkin's disease in adult men. Doctoral Thesis, Graduate School of Loyola University, Chicago, IL, 1983.

  15. Hellman S, Jaffe ES, DeVita VT. Hodgkin's disease. In: DeVita VT, Hellman S, Rosenberg SA, eds. Cancer, principles and practice of oncology. Philadelphia: Lippincott, 1989; i: 1696–1740.

    Google Scholar 

  16. Kornblith AB, Anderson J, Cella DF, et al. Hodgkin disease survivors at increased risk for problems in psychosocial adaptation. Cancer 1992; 70: 2214–2224.

    Google Scholar 

  17. Kornblith AB, Anderson J, Cella DF, et al. Comparison of psychosocial adaptation and sexual function of survivors of advanced Hodgkin disease treated by MOPP, ABVD or MOPP alternating with ABVD. Cancer 1992; 70: 2508–2516.

    Google Scholar 

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Norum, J., Wist, E.A. Quality of life in survivors of Hodgkin's disease. Qual Life Res 5, 367–374 (1996). https://doi.org/10.1007/BF00433921

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  • DOI: https://doi.org/10.1007/BF00433921

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