Abstract
The biocompatibility of Mg-PSZ ceramics aged to peak strength at 1100° C was assessed by in vitro and in vivo experiments. The former consisted of immersing the material in saline solution, boiling under reflux, for 1000 hours. A 6% loss in strength was the only discernible change in the ceramic. The in vivo experiments comprised implanting Mg-PSZ samples in the paraspinalis muscles of rabbits for 6 months. There was no significant adverse soft tissue response to the implants. Neither was there any change in the surface phase content, surface roughness or strength of the implants during the course of the experiment.
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References
H. S. Dobbs, J. Mater. Sci. 16 (1981) 1204.
I. C. Clarke, Eng. in Medicine 10 (1981) 115.
G. Heimke, private communication.
Idem, “Ceramics in Surgery”, edited by P. Vincenzini (Elsevier, Amsterdam, 1983).
R. H. J. Hannink and R. C. Garvie, J. Mater. Sci. 17 (1982) 2637.
R. C. Garvie, Second International Conference on the Science and Technology of Zirconia (Zirconia-83) Stuttgart, June 1983.
R. C. Garvie, M. F. Goss and C. Urbani, Sci. Ceram. 12 (1984) 575.
S. T. Gulati, J. D. Helfinstine and A. D. Davis, Bull. Amer. Ceram. Soc. 59 (1980) 211.
B. Mussler, M. V. Swain and N. Claussen, J. Amer. Ceram. Soc. 65 (1982) 566.
J. T. Hogan, M. V. Swain and J. Field, Fracture 3 (1977) 993.
W. Dawihl and G. Altmeyer, Zeit. f. Werkstofftech. 7 (1976) 208.
H. H. Sturhahn, W. Dawihl and G. Thamerus, Ber. Dt. Keram. Ges. 52 (1975) 84.
W. Dawihl and U. Dworak, Arch. Eisenhuttenwes. 41 (1976) 757.
M. V. Swain and M. F. Goss, CSIRO, Advanced Materials Laboratory Report No. AML-87-10 (1981).
R. T. Pascoe and R. C. Garvie, “Ceramic Microstructures '76”, edited by R. M. Fulrath and J. A. Pask (Westview, Boulder, 1977).
M. V. Swain, J. Mater. Sci. Lett. 15 (1980) 1577.
R. T. Pascoe, R. H. J. Hannink and R. C. Garvie, Sci. Ceram. 9 (1977) 447.
R. C. Garvie and P. S. Nicholson, J. Amer. Ceram. Soc. 55 (1972) 152.
S. F. Hulbert, J. J. Klawitter and W. C. Richardson, Jr., 3rd Annual Meeting of the Biomedical Engineering Society, Baltimore, April 1972.
J. Scales, private communication.
F. Daniels and R. A. Alberty, “Physical Chemistry”, 2nd edn (Wiley, New York and London, 1963).
S. M. Wiederhorn, “Mechanical and Thermal Properties of Ceramics”, National Bureau of Standards Special Publication 303 (1968) 217.
G. W. Snedecor and W. G. Cochran, “Statistical Methods”, 6th edn (Iowa State University, Ames, 1969).
S. A. Bortz and E. J. Onesto, Bull. Amer. Ceram. Soc. 52 (1973) 898.
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Garvie, R.C., Urbani, C., Kennedy, D.R. et al. Biocompatibility of magnesia-partially stabilized zirconia (Mg-PSZ) ceramics. J Mater Sci 19, 3224–3228 (1984). https://doi.org/10.1007/BF00549808
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DOI: https://doi.org/10.1007/BF00549808