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Pick's disease with compound intraneuronal inclusion bodies

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Summary

This report presents findings from an unusual case of Pick's disease that was characterized by unique compound inclusion bodies consisting of a small eosinophilic core within the hematoxylinophilic Pick bodies. These structures are compared to other inclusions observed in Pick's disease and motor neuron disease.

Zusammenfassung

Diese Mitteilung betrifft Befunde eines ungewöhnlichen Falles von Pickscher Krankheit, der durch unikale Einschlußkörperchen mit kleinem eosinophilen Zentrum innerhalb der hämatoxylinophilen Pick bodies (Silberkugeln) gekennzeichnet war. Diese Gebilde werden mit anderen Einschlüssen verglichen, die man bei der Pickschen Krankheit und bei Erkrankungen des motorischen Neurons findet.

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References

  • Alzheimer, A.: Über eigenartige Krankheitsfälle des späteren Alters. Z. ges. Neurol. Psychiat.4, 356–385 (1911).

    Google Scholar 

  • Hirano, A., Dembitzer, H. M., Kurland, L. T., Zimmerman, H. M.: The fine structure of some intraganglionic alterations. J. Neuropath. exp. Neurol.27, 167–182 (1968b).

    Google Scholar 

  • —, Tuazon, R., Zimmerman, H. M.: Neurofibrillary changes, granulovacuolar bodies and argentophilic globules observed in tuberous sclerosis. Acta neuropath. (Berl.)11, 257–261 (1968a).

    Google Scholar 

  • Lüers, Th., Spatz, H.: Picksche Krankheit (Progressive umschriebene Großhirnatrophia). In: Handb. d. spez. pathol. Anat. Histol., Bd. 13/1, S. 614–715. Berlin-Göttingen-Heidelberg: Springer 1957.

    Google Scholar 

  • Pick, A.: Über die Beziehungen der senilen Hirnatrophie zur Aphasie. Prag. med. Wschr.17, 165–167 (1892).

    Google Scholar 

  • Rewcastle, N. B., Ball, M. J.: Electron microscopic structure of the “inclusion bodies” in Pick's disease. Neurology (Minneap.)18, 1205–1213 (1968).

    Google Scholar 

  • Schochet, S. S., Jr., Hardman, J. M., Ladewig, P. P., Earle, K. M.: Intraneuronal conglomerates in sporadic motor neuron disease. Arch. Neurol. (Chic.)20, 548–553 (1969).

    Google Scholar 

  • —, Lampert, P. W., Lindenberg, R.: Fine structure of the Pick and Hirano bodies in a case of Pick's disease. Acta neuropath. (Berl.)11, 330–337 (1968).

    Google Scholar 

  • Seitelberger, F.: General Neuropathology of degenerative processes of the nervous system. In: Ehrenpries, S., and O. C. Solnitzky (Eds.): Neurosciences Research, Vol. 2, pp. 253–299 New York: Academic Press 1969.

    Google Scholar 

  • Williams, H. W.: The peculiar cells of Pick's disease. Arch. Neurol. Psychiat. (Chic.)34, 508–519 (1935).

    Google Scholar 

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Authors and Affiliations

  1. Department of Pathology, University of Iowa College of Medicine, 52240, Iowa City, Iowa, USA

    S. S. Schochet Jr. & K. M. Earle

  2. Neuropathology Branch, Armed Forces Institute of Pathology, Washington

    S. S. Schochet Jr. & K. M. Earle

Authors
  1. S. S. Schochet Jr.
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  2. K. M. Earle
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Schochet, S.S., Earle, K.M. Pick's disease with compound intraneuronal inclusion bodies. Acta Neuropathol 15, 293–297 (1970). https://doi.org/10.1007/BF00684727

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  • DOI: https://doi.org/10.1007/BF00684727

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