Abstract
This article reports three studies that taken together support two hypotheses: (a) that the stressed power motivation syndrome is associated with relatively low natural killer cell activity (NKCA) and (b) that the unstressed affiliation motivation syndrome is associated with higher NKCA. In Study 1, college students who were relatively high in stressed power motivation had significantly lower NKCA than did their peers. In addition, students high in unstressed affiliation motivation had significantly greater NKCA than did those showing less evidence of this syndrome. Study 2 replicated these findings on a sample of middle-class men. In Study 3, which tested the hypotheses among adult patients from a Health Maintenance Organization, results were in the same direction but less significant. Meta-analyses clearly indicate that the combined evidence from the three studies reliably supports both hypotheses.
Similar content being viewed by others
References
Atkinson, J. W. (ed.). (1958).Motives in Fantasy, Action, and Society, Van Nostrand, New York.
Boyatzis, R. E. (1973). Affiliation motivation. In McClelland, D. C., and Steele, R. S. (eds.),Human Motivation, General Learning, Morristown, NJ, pp. 252–276.
Cook, T. D., and Campbell, D. T. (1979).Quasi-Experimentation: Design and Analysis Issues for Field Settings, Rand McNally, Chicago.
Cornfeld, D., and Hubbard, J. P. (1961). A four-year study of beta-hemolytic streptococci in 64 school children.N. Engl. J. Med. 264: 211.
Dorian, B. J., Keystone, E., Garfinkel, P. E., and Brown, G. M. (1982). Aberrations in lymphocyte subpopulations and functions during psychological stress.Clin. Exp. Immunol. 50: 132–138.
Goldberg, E. L., and Comstock, G. W. (1980). Epidemiology of life events: Frequencies in general populations.Am. J. Epidemiol. 111: 736–752.
Hays, W. L. (1981).Statistics, Holt, Rinehart & Winston, New York.
Hedges, L. V., and Olkin, I. (1985).Statistical Methods for Meta-Analysis, Academic Press, New York.
Herberman, R. B. (1982). Nautral killer cells.Hosp. Pract. April: 93–103.
Herberman, R. B., and Holden, H. T. (1978). Natural cell-mediated immunity. In Klein, G., and Weinhouse, S. (eds.),Advances in Cancer Research, Academic Press, New York, Vol. 27, pp. 305–377.
Holmes, T. H., and Masuda, M. (1974). Life change and illness susceptibility. In Dohrenwend, B. S., and Dohrenwend, B. P. (eds.),Stressful Life Events: Their Nature and Effects, Wiley, New York.
Hurst, M. W. (1979). Life changes and psychiatric symptom development: Issues of content, scoring, and clustering. In Barrett, J., and Rose, R. (eds.),Stress and Mental Illness, Raven Press, New York.
James, W. E. S., Badger, G. F., and Dingle, J. H. (1960). A study of illness in a group of Cleveland families: XIX. The epidemiology of the acquisition of group A streptococci and of associated illness.N. Engl. J. Med. 262: 687.
Jemmott, J. B., III (1987). Social motives and susceptibility to disease: Stalking individual differences in health risks.J. Personal. 55: 267–298.
Jemmott, J. B., III, and Locke, S. E. (1984). Psychosocial factors, immunologic mediation, and human susceptibility to infectious diseases: How much do we know?Psychol. Bull. 95: 78–108.
Jemmott, J. B., III, and Magloire, K. (1988). Academic stress, social support, and secretory immunoglobulin A.J. Personal. Soc. Psychol. 55(5): 803–810.
Jemmott, J. B., III, and McClelland, D. C. (1989). Secretory IgA as a measure of resistance to infectious disease: Comments on Stone, Cox, Valdimarsdottir, and Stone (1987).Behav. Med. 15: 63–71.
Jemmott, J. B., III, Borysenko, J. Z., Borysenko, M., McClelland, D. C., Chapman, R., Meyer, D., and Benson, H. (1983). Academic stress, power motivation, and decrease in salivary secretory immunoglobulin A secretion rate.Lancet 1: 1400–1402.
Kiecolt-Glaser, J. K., Garner, W., Speicher, C., Penn, G. M., Holliday, J., and Glaser, R. (1984a). Psychosocial modifiers of immunocompetence in medical students.Psychosom. Med. 46: 7–14.
Kiecolt-Glaser, J. K., Ricker, D., Messick, G., Speicher, C. E., Garner, W., and Glaser, R. (1984b). Urinary cortisol, cellular immunocompetency, and loneliness in psychiatry patients.Psychosom. Med. 46: 15–24.
Kiecolt-Glaser, J. K., Glaser, R., Williger, D., Stout, J., Messick, G., Sheppard, S., Ricker, D., Romisher, S. C., Briner, W., Bonnell, G., and Donnerberg, R. (1985). Psychosocial enhancement of immunocompetence in a geriatric population.Health Psychol. 4: 23–41.
Kronfol, Z., Silva, J., Jr., Greden, J., Dembinski, S., Gardner, R., and Carroll, B. (1983). Impaired lymphocyte function in depressive illness.Life Sci. 33: 241–247.
Lazarus, R. S. (1970). Cognitive and personality factors underlying stress and coping. In Levine, S., and Scotch, N. (eds.),Social Stress, Aldine, Chicago.
Linn, B. S., Linn, M. W., and Jenson, J. (1982). Degree of depression and immune responsiveness.Psychosom. Med. 44: 128 (abstract).
Locke, S. E., Kraus, L., Leserman, J., Hurst, M. W., Heisel, J. S., and Williams, R. M. (1984). Life change stress, psychiatric symptoms, and natural killer cell activity.Psychosom. Med. 46: 441–453.
Lundy, A. (1985). The reliability of the Thematic Apperception Test.J. Personal. Assess. 49: 141–145.
Mason, J. W. (1975). A historical view of the stress field. II.J. Hum. Stress 1(2): 22–36.
McAdams, D. P., and Constantian, C. A. (1983). Intimacy and affiliation motives in daily living: An experience sampling analysis.J. Personal. Soc. Psychol. 45: 851–861.
McClelland, D. C. (1975).Power: The Inner Experience, Irvington, New York.
McClelland, D. C. (1980). Motive dispositions: The merits of operant and respondent measures. In Wheeler, L. (ed.),Review of Personality and Social Psychology (Vol. 1), Sage, Beverly Hills, CA.
McClelland, D. C. (1985).Human Motivation, Scott, Foresman, Glenview, IL.
McClelland, D. C., and Jemmott, J. B., III (1980). Power motivation, stress, and physical illness.J. Hum. Stress 6(4): 6–15.
McClelland, D. C., Alexander, C., and Marks, E. (1982). The need for power, stress, immune function, and illness among male prisoners.J. Abnorm. Psychol. 91: 61–70.
McClelland, D. C., Floor, E., Davidson, R. J., and Saron, C. (1980). Stressed power motivation, sympathetic activation, immune function, and illness.J. Hum. Stress 6(2): 11–19.
Mims, C. A. (1986).The Pathogenesis of Infectious Disease. Academic Press, New York.
Mosteller, F. M., and Bush, R. R. (1954). Selected quantitative techniques. In Lindzey, G. (ed.),Handbook of Social Psychology (Vol. 1), Addison-Wesley, Cambridge, MA.
Palmblad, J. (1981). Stress and immunocompetence: Studies in man. In Ader, R. (ed.),Psychoneuroimmunology, Academic Press, New York, pp. 229–257.
Pross, H. F., and Baines, M. G. (1982). Studies of natural killer cells. I. In vivo parameters affecting normal cytotoxic function.Int. J. Cancer, 29: 383–390.
Rosenthal, R. (1978). Combining results of independent studies.Psychol. Bull. 85: 185–193.
Rosenthal, R. (1984).Meta-Analytic Procedures for Social Research, Sage, Beverly Hills, CA.
Rosenthal, R., and Rosnow, R. L. (1985).Contrast Analysis: Focused Comparisons in the Analysis of Variance, Cambridge University, New York.
Rossen, R. D., Butler, W. T., Waldman, R. H., Alford, R. H., Hornick, R. B., Togo, Y., and Kasel, J. A. (1970). The protein in nasal secretions.JAMA 211: 1157–1161.
Stone, A., Cox, D. S., Valdimarsdottir, H., and Neale, J. M. (1987). Secretory IgA as a measure of immunocompetence.J. Hum. Stress 13: 136–140.
Tomasi, T. B., and Grey, H. M. (1972). Structure and function of immunoglobulin A.Prog. Allergy 16: 81–213.
Webb, E. J., Campbell, D. T., Schwartz, R. D., Sechrest, K., and Grove, J. B. (1981).Nonreactive Measures in the Social Sciences, Houghton Mifflin, Boston, MA.
Winer, B. J. (1971).Statistical Principles in Experimental Design, McGraw-Hill, New York.
Winter, D. G. (1973).The Power Motive, Free Press, New York.
Winter, D. G. (1980).Correcting Projective Test Scores for the Effect of Significant Correlation with Length of Protocol (Technical Note), McBer and Company, Boston, MA.
Winter, D. G., and Stewart, A. J. (1977). Power motive reliability as a function of retest instructions.J. Consult. Clin. Psychol. 45: 436–440.
Author information
Authors and Affiliations
Additional information
This work was supported in part by Grant CA-29155 from the National Cancer Institute, Grant MH-1589 from the National Institute of Mental Health, Grant RR-01032 from the National Institutes of Health General Clinical Research Centers Program of the Division of Research Resources, Biomedical Research Support Grant RR-5487 (University Hospital), and a grant from the John D. and Catherine T. MacArthur Foundation. Additional support was provided under the Office of Naval Research Contract N-00014-79-C-1068 with funds of the Naval Medical Research and Developmental Command. The opinions or assertions contained herein are those of the authors and are not to be construed as official or reflecting the views of the Navy Department or Naval Service at large.
Rights and permissions
About this article
Cite this article
Jemmott, J.B., Hellman, C., McClelland, D.C. et al. Motivational syndromes associated with natural killer cell activity. J Behav Med 13, 53–73 (1990). https://doi.org/10.1007/BF00844899
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00844899