Skip to main content
Log in

Indirect radionuclide cystography: a sensitive technique for the detection of vesico-ureteral reflux

  • Original Article
  • Published:
Pediatric Nephrology Aims and scope Submit manuscript

Abstract

The detection or exclusion of vesico-ureteral reflux (VUR) has classically been by micturating cystourethrography (MCUG). Radionuclide cystography will detect VUR but fails to provide the same detailed anatomical informations as MCUG. This study allowed a comparison of indirect radionuclide cystography (IRC) and MCUG in 65 children. Renal reflux was detected by IRC in 32% of renal units, while VUR was seen in 36% by MCUG. When a comparison was made with MCUG, IRC had a sensitivity of 74.1% and a specificity of 90.5%. The markedly reduced radiation dose, avoidance of a bladder catheter plus the ability to monitor the urinary tract constantly during the entire procedure should ensure that IRC is the examination of choice in follow-up studies for VUR in all toilet-trained children.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Winter CC (1959) A new test for vesico-ureteral reflux. An external technique using radioisotopes. J Urol 81: 105–116

    Google Scholar 

  2. Rothwell DL, Constable AR, Albrecht M (1977) Radionuclide cystography in the investigation of vesico-ureteric reflux in children. Lancet I: 1072–1075

    Google Scholar 

  3. Handmaker H, McRae J, Buck EG (1973) Intravenous radionuclide voiding cystography (IRVC). Radiology 108: 703–705

    Google Scholar 

  4. Merrick MV, Uttley WS, Wild R (1979) A comparison of two techniques in detecting vesico-ureteric reflux. Br J Radiol 50: 792–795

    Google Scholar 

  5. Willi UV, Treves ST (1985) Radionuclide voiding cystography. In: Treves ST (ed) Paediatric nuclear medicine. Springer, New York Berlin Heidelberg, pp 105

    Google Scholar 

  6. Conway JJ, Belman AB, King LR (1974) Direct and indirect radionuclide cystography. Semin Nucl Med 4: 197–211

    Google Scholar 

  7. Pollet JE, Sharp PF, Smith FW (1981) Intrvenous radionuclide cystography for the detection of vesico-renal reflux. J Urol 125: 75–78

    Google Scholar 

  8. Nielsen JB, Jensen FT, Munch JT, Charles P, Djurhuis JC (1985) The diagnosis of vesico-ureteral reflux. Radiologic and medicine methods. Scand J Urol Nephrol 19:109–112

    Google Scholar 

  9. Bower G, Lovegrove FT, Geijsel H, Scaff A van der, Guelfi g (1985) Comparison of direct and indirect radionuclide cystography. J. Nucl Med 26: 465–468

    Google Scholar 

  10. Carlsen O, Lukman B, Nathan E (1986) Indirect radionuclide renocystography for determination of vesico-ureteral reflux in children. Eur J Nucl Med 12: 205–210

    Google Scholar 

  11. Chapman SJ, Chantler C, Haycock GB, Maisey MN, Saxton HM (1988) Radionuclide cystography in vesico-ureteric reflux. Arch Dis Child 63: 650–651

    Google Scholar 

  12. Majd M (1986) Comparison of direct and indirect isotope cystography (abstract) Radiology 158: 228

    Google Scholar 

  13. Conway JJ, Kruglik GD (1976) Effectiveness of direct and indirect radionuclide cystography in detecting vesicoureteral reflux. J Nucl Med 17: 81–83

    Google Scholar 

  14. Peters AM, Morony S, Gordon I (1990) Indirect radionuclide cystography demonstrates reflux under physiological conditions. Clin. Radiol 41: 44–47

    Google Scholar 

  15. Cremin BJ (1979) Observations on vesico ureteric reflux and intrarenal reflux. A review and survey of material. Clin Radiol 30: 607–621

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gordon, I., Peters, A.M. & Morony, S. Indirect radionuclide cystography: a sensitive technique for the detection of vesico-ureteral reflux. Pediatr Nephrol 4, 604–606 (1990). https://doi.org/10.1007/BF00858633

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00858633

Key words

Navigation