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Slow subcutaneous immunoglobulin therapy in a patient with reactions to intramuscular immunoglobulin

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Abstract

A 35-year-old man with common variable hypogammaglobulinemia had repeated anaphylactic reactions to intramuscular human immune serum globulin (HISG), preventing him from receiving the injections. He was able to tolerate slow subcutaneous HISG infusions without local or systemic side effects at a dose of 12 ml/week given at a rate of 2 ml/hr. He has been maintained on these infusions for 2 years in an infection-free state.

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References

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Author notes

  1. Michael J. Welch MD

    Present address: Department of Clinical Research, Scripps Clinic and Research Foundation, 10666 North Torrey Pines Road, 92037, La Jolla, California

Authors and Affiliations

  1. Department of Pediatrics and the Center for Interdisciplinary Research in Immunologic Diseases, UCLA School of Medicine, 90024, Los Angeles, California

    Michael J. Welch MD & E. Richard Stiehm MD

Authors
  1. Michael J. Welch MD
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  2. E. Richard Stiehm MD
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Welch, M.J., Stiehm, E.R. Slow subcutaneous immunoglobulin therapy in a patient with reactions to intramuscular immunoglobulin. J Clin Immunol 3, 285–286 (1983). https://doi.org/10.1007/BF00915353

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  • DOI: https://doi.org/10.1007/BF00915353

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