Skip to main content
Log in

Subretinal neovascular membranes associated with chronic membranoproliferative glomerulonephritis type II

  • Clinical Investigations
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Subretinal neovascular membranes were observed in three patients with chronic membranoproliferative glomerulonephritis type II (dense deposit disease). The first signs of glomerulonephritis occurred at respective ages of 13, 10 and 10 years; subretinal neovascular membranes were noted at respective ages of 25, 32 and 32 years. All patients had bilateral, widespread retinal pigment epithelial abnormalities. Our findings indicate that subretinal neovascularization is a complication of dense deposit disease. In one patient, the early recognition and laser treatment of an extrafoveal subretinal neovascular membrane prevented further loss of vision.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Duvall-Young J, MacDonald M, McKechnie N (1989) Fundus changes in (type II) mesangiocapillary glomerulonephritis simulating drusen: a histopathological report. Br J Ophthalmol 73:297–302

    Google Scholar 

  2. Duvall-Young J, Short CD, Raines MF, Gokal R, Lawler W (1989) Fundus changes in mesangiocapillary glomerulonephritis type II: clinical and fluorescein angiographic findings. Br J Ophthalmol 73:900–906

    Google Scholar 

  3. Ormos J, Magori A, Sonkodi S, Streitmann K (1979) Type II membranoproliferative glomerulonephritis with electron-dense basement membrane alteration in the spleen. Arch Pathol Lab Med 103:265–266

    Google Scholar 

  4. Raines MF, Duvall-Young J, Short CD (1989) Fundus changes in mesangiocapillary glomerulonephritis type 11: vitreous fluorophotometry. Br J Ophthalmol 73:907–910

    Google Scholar 

  5. Thorner P, Baumal R (1982) Extraglomerular dense deposits in dense deposit disease. Arch Pathol Lab Med 106:628–631

    Google Scholar 

  6. West CD, McAdams AJ (1983) Membranoproliferative glomerulonephritis. In: Massry SG, Glassock RS (eds) Textbook of nephrology. Williams and Wilkins, Baltimore, pp 6.46–6.52

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Leys, A., Michielsen, B., Leys, M. et al. Subretinal neovascular membranes associated with chronic membranoproliferative glomerulonephritis type II. Graefe's Arch Clin Exp Ophthalmol 228, 499–504 (1990). https://doi.org/10.1007/BF00918479

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00918479

Keywords

Navigation