Summary
We report the case of a 58 year old woman with an epidermoid cyst of the right cerebello-pontine angle that was subtotally excised. She recurred 2 years later and received radiotherapy with resolution of symptoms and shrinkage of the cyst. The natural history of epidermoid cysts and the role of radiotherapy in their management is discussed.
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References
Russell DS, Rubinstein LJ: Pathology of tumors of the central nervous system (3 ed). Edward Arnold Ltd, London, 1971, p 429
Salazar J, Vaquero J, Saucedo G, Bravo G: Posterior fossa epidermoid cysts. Acta Neurochir (Wien) 85: 34–39, 1987
Conley FK: Epidermoid and dermoid tumors: Clinical features and management. In: Wilkins RH, Rengachary SS (eds) Neurosurgery. McGraw-Hill Book Co, New York, 1985, pp 668–673
Berger MS, Wilson CB: Epidermoid cysts of the posterior fossa. J Neurosurg 62: 214–219, 1985
Altschuler EM, Jungreis CA, Sekhar LN, Jannetta PJ, Sheptak PE: Operative treatment of intracranial epidermoid cysts and cholesterol granulomas: Report of 21 cases. Neurosurgery 26: 606–613, 1990
Yasargil MG, Abernathey CD, Sarioglu AC: Microsurgical treatment of intracranial dermoid and epidermoid tumors. Neurosurgery 24: 561–567, 1989
Franklin JK, Wise BL: Intracranial epidermoid and dermoid tumors. J Neurosurg 16: 564–569, 1959
Rajan A, Ashley S, Gorman C, Jose CC, Horwich A, Bloom HJG, Marsh H, Brada M: Craniopharyngioma-long term results following limited surgery and radiotherapy. Radiother Oncol 26: 1–10, 1993
Alvord EC: Growth rates of epidermoid tumors. Ann Neurol 2: 367–370, 1977
Tannock IF: Tumor growth and cell kinetics. In: Tannock IF, Hill RP (eds) The basic science of oncology. Pergamon Press, New York, 1987, pp 140–159
Collins VP, Loeffler RK, Tivey H: Observations on growth rates of human tumors. Am J Roentgenol Radium Ther Nucl Med 76: 988–1000, 1956
Rothberg S, Crounse RG, Lee JL: Glycine-C14 incorporation into the proteins of normal stratum corneum and the abnormal stratum corneum of psoriasis. J Invest Dermatol 37: 497–505, 1961
Abramson RC, Morawetz RB, Schlitt M: Multiple complications from an intracranial epidermoid cyst: case report and literature review. Neurosurgery 24: 574–578, 1989
Haig PV: Primary epidermoids of the skull including one with malignant change. AJR 76: 1076–1080, 1956
Fox H, South EA: Squamous cell carcinoma developing in an intracranial epidermoid cyst (cholesteatoma). J Neurol Neurosurg Psychiatry 28: 276–281, 1965
Netsky MG: Epidermoid tumors. Review of the literature. Surg Neurol 29: 477–483, 1988
Wong SW, Ducker TB, Powers JN: Fulminating parapontine epidermoid carcinoma in a four-year-old boy. Cancer 37: 1525–1531, 1976
Lewis AJ, Cooper PW, Kassel EE, Schwartz ML: Squamous cell carcinoma arising in a suprasellar epidermoid cyst. Case report J Neurosurg 59: 538–541, 1983
Geara FB, Peters LJ, Ang KK, Wike JL, Brock WA: Radiosensitivity measurement of keratinocytes and fibroblasts from radiotherapy patients. Int J Radiat Oncol Biol Phys 24: 287–293, 1992
Hall EJ: Radiobiology for the radiologist (4 ed). JB Lippincott Co, Philadelphia, 1994, p 477
Al-Mefty O, Kersh JE, Routh A, Smith RR: The long-term side effects of radiation therapy for benign brain tumors in adults. J Neurosurg 73: 502–512, 1990
Emami B, Lyman J, Brown A, Coia L, Goitein M, Munzenrider JE, Shank B, Solin LJ, Wesson M: Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 21: 109–122, 1991
Sheline GE, Wara WM, Smith V: Therapeutic irradiation and brain injury. Int J Radiat Oncol Biol Phys 6: 1215–1228, 1980
Tsang RW, Laperriere NJ, Simpson WJ, Brierley J, Panzarella T, Smyth HS: Glioma arising after radiation therapy for pituitary adenoma. Cancer 72: 2227–2233, 1993
Brada M, Ford D, Ashley S, Bliss JM, Crowley S, Mason M: Risk of second brain tumor after conservative surgery and radiotherapy for pituitary adenoma. Br Med J 304: 1343–1346, 1992
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Parikh, S., Milosevic, M., Wong, C.S. et al. Recurrent intracranial epidermoid cyst treated with radiotherapy. J Neuro-Oncol 24, 293–297 (1995). https://doi.org/10.1007/BF01052846
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DOI: https://doi.org/10.1007/BF01052846