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In vivo and in vitro expression of canine distemper viral proteins in dogs and non-domestic carnivores

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Summary

The occurrence of the nucleo-, phospho-, matrix, fusion, and hemagglutinin proteins of the canine distemper virus (CDV) was investigated immunocytochemically in the brains of 3 dogs, 6 stone martens, 1 polecat, and 1 weasel. In addition, viral protein expression was studied in primary brain cell cultures of the 3 dogs after co-cultivation with Vero cells. Immunohistochemically, only minor differences, restricted to the H-4 epitope, were noted between the various species and CDV isolates. The data presented indicate that the mustelid virus is antigenically not distinct from the canine morbillivirus.

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Authors and Affiliations

  1. Institut für Veterinär-Pathologie der Justus-Liebig-Universität Giessen, Giessen, Federal Republic of Germany

    Susanne Alldinger, W. Baumgärtner & Petra van Moll

  2. Virus Department, Central Microbiological Laboratory of Stockholm County Council, Stockholm, Sweden

    C. Örvell

Authors
  1. Susanne Alldinger
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  2. W. Baumgärtner
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  3. Petra van Moll
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  4. C. Örvell
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Alldinger, S., Baumgärtner, W., van Moll, P. et al. In vivo and in vitro expression of canine distemper viral proteins in dogs and non-domestic carnivores. Archives of Virology 132, 421–428 (1993). https://doi.org/10.1007/BF01309550

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  • DOI: https://doi.org/10.1007/BF01309550

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