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Subarachnoid buprenorphine administered by implantable micropumps

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Summary

This report concerns 23 patients, the majority of whom are suffering from low back and chest pain caused by chest, urological or gynaecological cancer.

These patients were treated with subarachnoid burpenorphine, administered in a single bolus or by slow infusion from micropumps, at a daily dose adapted to patient's need (0.06–0.15 mg). The painful symptomatology was successfully controlled in all the cases treated, allowing the patients to live a virtually normal life. In no cases was respiratory depression or tolerance observed.

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Authors and Affiliations

  1. Clinica Neurochirurgica, Università di Genova, Italy

    N. Francaviglia, C. Silvestro, F. Carta & V. Davini

  2. Clinica Neurochirurgica, Università di Sassari, Italy

    C. Perria

  3. Centro Ricerche, Boehringer Biochemia Robin S.p.A., Milano, Italy

    I. Scaricabarozzi & P. V. Cipolla

Authors
  1. N. Francaviglia
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  2. C. Silvestro
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  3. F. Carta
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  4. V. Davini
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  5. C. Perria
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  6. I. Scaricabarozzi
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  7. P. V. Cipolla
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Francaviglia, N., Silvestro, C., Carta, F. et al. Subarachnoid buprenorphine administered by implantable micropumps. Acta neurochir 102, 62–68 (1990). https://doi.org/10.1007/BF01402188

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