Summary
With the aim of understanding better the behaviour of an uncommon lesion such as the choroid plexus papilloma, we have analysed a surgical series of 33 cases operated on at the Neurosurgical Department, University of Rome “La Sapienza”, between 1955 and 1992 and have reviewed the relevant literature. Our results support the view that a radical resection of these lesions, which if removed entirely, carry a very good prognosis. The hydro-cephalus should be treated only if persistent.
Adjuvant treatment such as radiotherapy and chemotherapy should be reserved for specific cases.
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Arseni C, Costantinescu A, Danaila L, Istrate C (1974) The choroid plexus papillomas. Neurochirurgia 17: 121–128
Bielschowsky M, Unger E (1906) Zur Kenntnis der primären Epithelgeschwulste der Adergeflechte des Gehirns. Arch Klin Chir 81: 61–82
Bohm E, Strang R (1961) Choroid plexus papillomas. J Neurosurg 18: 493–500
Boyd MC, Steinbock MB (1987) Choroid plexus tumours: problems in diagnosis and management. J Neurosurg 66: 800–805
Carpenter DB, Michelsen W Jost, Hays AP (1982) Carcinoma of the choroid plexus. J Neurosurg 56: 722–727
Coates TL, Hinshaw DB, jr, Peckman N, Thompson JR, Hasso AN, Holshouser BA, Knierim DS (1989) Pediatric choroid plexus neoplasms: MR, CT, and pathologic correlation. Radiology 173: 81–88
Coffin CM, Wick MR, Braun JT, Dehner LF (1986) Choroid plexus neoplasms: clinicopathological and immuno-histochemical studies. Am J Surg Pathol 10 (6): 394–404
Cruz-Sanchez FF, Rossi M Lo, Hughes JT, Coakham HB, Figols J, Eynaud PM (1989) Choroid plexus papillomas: an immunohistological study of 16 cases. Hystopathology 15: 61–69
Delfini R, Acqui M, Oppido PA, Capone R, Santoro A, Ferrante L (1991) Tumours of the lateral ventricles. Neurosurg Rev 14: 127–133
Doglioni C, Dell'Orto P, Coggi G, Luzzolino P, Bontempini L, Viale G (1987) Choroid plexus tumours. An immunocyto-chemical study with particular reference to the coexpression of intermediate filament proteus. Am J Pathol 127: 519–529
Dohrmann GJ, Collins JC (1975) Choroid plexus carcinoma. J Neurosurg 43: 225–232
Domingues Romev C, Taveras JM, Reimer P, Rosen BR (1991) Foramen magnum choroid plexus papilloma with drop metastasis in the lumbar spine. AJNR 12: 564–565
Ellenbogen RG, Winston KR, Kupsky WJ (1989) Tumors of the choroid plexus in children. Neurosurgery 25: 327–335
Fortuna A, Celli P, Ferrante L, Turano C (1979) A review of papillomas of the third ventricle: one case report. J Neurosurg Sci 23: 61–76
Giavella-Borradori A, Zeltzer PM, Bodey B, Nelson M, Britton H, Marlin A (1992) Choroid plexus tumours in childhood. Response to chemotherapy and immunophenotypic profile using a panel of monoclonal antibodies. Cancer 69: 809–816
Gradin WC, Taylor C, Fruin AH (1983) Choroid plexus papilloma of the third ventricle: case report and review of the literature. Neurosurgery 12: 217–220
Guidetti G, Spallone A (1981) The surgical treatment of choroid plexus papillomas: the results of 27 years' experience. Neurosurg Rev 4: 129–137
Gutin PH (1984) Preliminary experience with I125 brachytherapy of paediatric brain tumours. In: Humphreys RP (ed) Concepts in paediatric neurosurgery V. Karger, Basel
Hawkins JC (1980) Treatment of choroid plexus papillomas in children: a brief analysis of twenty years' experience. Neurosurgery 6: 380–384
Hayakawa I, Fusiwara K, Tsuchida T, Aoki M (1979) Choroid plexus carcinoma with metastasis to bone. Neurol Surg 7: 815–818
Herbert J, Cavallaro T, Dwork AJ (1990) A marker for primary choroid plexus neoplasms. Am J Pathol 136: 1317–1325
Heydermann E, Strudley I (1985) A new monoclonal antibody to epithelial membrane antigen (EMA) E-29. A comparison of its immunocytochemical reactivity with polyclonal Anti-EMA antibodies and with another monoclonal antibody HFMG-2. Br J Cancer 52: 355–361
Hisatashi I, Motoshige K (1991) Malignant choroid plexus papilloma of the IV ventricle. Childs Nerv Syst 7: 109–111
Hopper KD, Foley LC, Nieves NL, Smirniotopoulos J (1987) THe intraventricular extension of choroid plexus papillomas. AJNR 27: 445–450
James JE (1985) Choroid plexus papillomas. In: Wilkins RH, Rengachary SS (eds) Neurosurgery, Vol 1. McGraw-Hill, New York, pp 783–785
Jooma R, Grant DN (1983) Third ventricle choroid plexus papillomas. Childs Brain 10: 242–250
Jooma R, Hayward RD, Grant DN (1984) Intracranial neoplasms during the first year of life: analysis of one hundred consecutive cases. Neurosurgery 14: 31–41
Kimura M, Takayasu M, Suzuki Y, Negoro M, Nagasaka T, Nakashima N, Sugita K (1992) Primary choroid plexus papilloma located in the suprasellar region: case report. Neurosurgery 31: 563–566
Laurence KM (1974) The biology of choroid plexus papillomas and carcinomas of the lateral ventricle. In: Vinken PJ, Bruyns GW (eds) Handbook of clinical neurology. Tumours of the brain and skull, Part 2, Vol 17. North Holland, Amsterdam, Elsevier, New York, pp 555–595
Lena G, Genitori L, Molina J, Legatte JRS, Choux M (1990) Choroid plexus tumours in children. Review of 24 cases. Acta Neurochir (Wien) 106: 68–72
Lewis P (1967) Carcinoma of the choroid plexus. Brain 90: 177–186
Maria BL, Graham ML, Strauss LC, Wharam MD (1985) Response of a recurrent choroid plexus tumour to combination chemotherapy. J Neurooncol 3: 259–262
Matson DD, Crofton FDL (1960) Papilloma of the choroid plexus in childhood. J Neurosurg 17: 1002–1027
Matsushima T, Inoue T, Takeshita I, Fukui M, Iwaki T, Kitamoto T (1988) Choroid plexus papillomas: an immunohisto-chemical study with particular reference to the co-expression of pre-albumin. Neurosurgery 23: 384–389
Mc Girr SJ, Ebersold MJ, Scheithauer BW, Quast LN, Shaw EG (1988) Choroid plexus papillomas: long-term follow up results in a surgically treated series. J Neurosurg 69: 843–849
Muller W, Klein PJ, Vierbuchen MJ, Uhlenbruck G (1980) Lectin binding sites in choroid plexus and choroid plexus papillomas. Neurosurg Rev 3: 57–65
Namer IJ, Pamir MN, Benli K, Erbengi A, Ruacan S (1985) Carcinome primitif du plexus choroïde. Presentation de deux cas et revue de la litterature. Neurochirurgie 31: 429–434
Nathrath WBJ, Heidenkummer P, Bjorklund V, Bjorklund B (1985) Distribution of tumour polypeptide antigen (TPA) in normal human tissue. J Histochem Cytochem 33: 99–109
Pascual-Castroviejo I, Villarejo F, Perez-Higueras A, Morales C, Pascual-Pascual SI (1983) Childhood choroid plexus neoplasm. A study of 14 cases less than 2 years old. Eur J Pediatr 140: 51–56
Piquet V, De Tribolet N (1984) Choroid plexus papilloma of the cerebellopontine angle presenting as a subarachnoid hemorrhage: case report. Neurosurgery 15: 114–116
Raimondi AJ, Gutierrez FA (1975) Diagnosis and surgical treatment of choroid plexus papillomas. Childs Brain 1: 81–115
Russell DS, Rubinstein LJ (1989) Pathology of tumours of the nervous system, 5th Ed. Williams and Wilkins, Baltimore
Sahar A, Feinsod M, Beller AJ (1980) Choroid plexus papilloma: hydrocephalus and cerebrospinal fluid dynamics. Surg Neurol 13: 476–478
Spallone A, Guidetti G, Mercuri S, Russo A, Lerardi A, Silipo P (1982) Choroid plexus papillomas. Neuroradiological diagnosis. Neurochirurgia 25: 165–169
Thompson SR, Harwood-Nash RC, Fitz CR (1973) The neuro-radiology of childhood choroid plexus neoplasm. Am J Roentgenol 118: 116–133
Tomita T, McLone DG (1985) Brain tumors during the first twenty-four months of life. Neurosurgery 17: 913–919
Tomita T, McLone DG, Flannery AM (1988) Choroid plexus papillomas in neonates, infants and children. Pediatr Neurosci 14: 23–30
Valladares JB, Perry RH, Kalbag RM (1980) Malignant choroid plexus papilloma with extraneural metastasis. Case report. J Neurosurg 52: 251–255
Velasco-Siles JM, Raimondi AJ (1982) Choroid plexus papilloma. In: Section of Paediatric Neurosurgery of the American Association of Neurological Surgery (ed) Pediatric neurosurgery. Surgery of the developing nervous system. Grune and Stratton, New York, pp 451–460
Vraa-Jensen G (1950) Papilloma of the choroid plexus with pulmonary metastasis. Acta Psychiatr Neurol (Köln) 25: 299–306
Wagle V, Melanson D, Ethier R, Bertrand G, Villemure JG (1987) Choroid plexus papilloma: magnetic resonance computed tomography and angiographic observations. Surg Neurol 27: 466–468
Zülch KJ (1956) Biologie und Pathologie der Hirngeschwülste. In: Zülch KJ, Christensen E (eds) Pathologische Anatomie der raumbedingenden intrakraniellen Prozesse. Handbuch der Neurochirurgie, Band 3. Springer, Berlin Göttingen Heidelberg, pp 1–70
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Tacconi, L., Delfini, R. & Cantore, G. Choroid plexus papillomas: Consideration of a surgical series of 33 cases. Acta neurochir 138, 802–810 (1996). https://doi.org/10.1007/BF01411257
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DOI: https://doi.org/10.1007/BF01411257