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Regional localization of carbonic anhydrase genesCA1 andCA3 on human chromosome 8

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Somatic Cell and Molecular Genetics

Abstract

The human carbonic anhydrase isozymes represent a family of homologous proteins which are important in respiratory function, fluid secretion, and maintenance of cellullar acid-base homeostasis. Using somatic cell genetic techniques we have mapped two of the CA genes (CA1and CA3)to human chromosome 8. In situ hybridization data demonstrates that both CA1and CA3map to the same region (q13–q22) of chromosome 8.

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Authors and Affiliations

  1. Department of Genetics and Biometry and the MRC Human Biochemical Genetics Unit, The Gallon Laboratory, University College London, Wolfson House, 4, Stephenson Way, NW1 2HE, London, UK

    Mary B. Davis, Lynne F. West, Julie C. Lloyd & Yvonne H. Edwards

  2. Department of Biochemistry, University College London, Gower Street, WC1E 6BT, London, UK

    Jonathan H. Barlow & Peter H. W. Butterworth

Authors
  1. Mary B. Davis
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  2. Lynne F. West
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  3. Jonathan H. Barlow
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  4. Peter H. W. Butterworth
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  5. Julie C. Lloyd
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  6. Yvonne H. Edwards
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Davis, M.B., West, L.F., Barlow, J.H. et al. Regional localization of carbonic anhydrase genesCA1 andCA3 on human chromosome 8. Somat Cell Mol Genet 13, 173–178 (1987). https://doi.org/10.1007/BF01534697

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  • DOI: https://doi.org/10.1007/BF01534697

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