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Craniocerebral epidermoids and dermoids

A review of 44 cases

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Summary

We review 40 epidermoids and 4 dermoids of the skull and brain treated surgically in our Department between 1976 and 1987. Fourteen were extradural and 30 intradural. The mean duration of symptoms was 3 years for extradural and 10 years for intradural tumours. Symptoms varied with tumour site, in some sites being helpful in differential diagnosis. Skull X-rays and CT were the key diagnostic investigations in extradural and CT in intradural lesions, the latter, with few exceptions, presenting a characteristic CT scan. In 7 cases MRI supplied important details on the tumour boundaries. All the diploic and orbital lesions were removed totally, with a good outcome. Twelve of the intradural lesions were removed totally, 9 subtotally and 9 partially, with a good outcome in 21 patients and a poor outcome in 4; 5 patients died. Outcome was unrelated to degree of removal.

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References

  1. Backer DP, Benyo R, Roessmann U (1967) Glial origin of monstrocellular tumour: case report of prolonged survival. J Neurosurg 26: 72–77

    Google Scholar 

  2. Bingas B (1964) Das monstrocelluläre Sarkom des Gehirns. Arch Psychiatr Nervenkr 205: 223–236

    Google Scholar 

  3. Brooks WH, Markesbery WR, Gupta GDet al (1978) Relationship of lymphocyte invasion and survival of brain tumour patients. Ann Neurol 4: 219–224

    Google Scholar 

  4. Brucher JM (1964) The classification and diagnosis of intracranial sarcomas. Acta Neurochir (Wien) [Suppl] 10: 190–200

    Google Scholar 

  5. Burger PC, Vollmer RT (1980) Histologic factors of prognostic significance in the glioblastoma multiforme. Cancer 46: 1179–1186

    Google Scholar 

  6. Burger PC, Vogel FS, Green SB, Strike TA (1985) Glioblastoma multiforme and anaplastic astrocytoma. Pathologic criteria and prognostic implications. Cancer 56: 1106–11

    Google Scholar 

  7. Dohrmann GJ, Farwell JR, Flannery JT (1976) Glioblastoma multiforme in children. J Neurosurg 44: 442–448

    Google Scholar 

  8. Frankel SA, German WJ (1958) Glioblastoma multiforme. Review of 219 cases with regard to natural history, pathology, diagnostic methods and treatment. J Neurosurg 15: 489–503

    Google Scholar 

  9. Garcia-Bengochea F, Collins GH (1969) Monstrocellular sarcoma of the brain: 6 year postoperative survival. Case report. J Neurosurg 31: 686–689

    Google Scholar 

  10. Gluszcz A (1970) Morphogenesis and evolution of intracerebral monstrocellular tumours (“Sarcoma monstrocellulare”). Clinical and histopathological study. Neuropathol Pol 8: 5–22

    Google Scholar 

  11. Gluszcz A, Alwasiak J, Papierz Wet al (1975) Morphological observations of dysplastic gliomas heterotransplanted to experimental animals. Acta Neuropathol (Berl) 31: 21–28

    Google Scholar 

  12. Gruszkiewicz J, Doron J, Griffel Bet al (1965) Monstrocellular sarcoma in a child. Zbl Neurochir 26: 17–22

    Google Scholar 

  13. Gullotta F, Bettag W (1967) Zur Frage der längeren Überlebenszeit bei Glioblastomen. Acta Neurochir (Wien) 16: 122–128

    Google Scholar 

  14. Hadfield MG, Silverberg SG (1972) Light and electromicroscopy of giant cell glioblastoma. Cancer 30: 989–996

    Google Scholar 

  15. Heyerdahl Strom E, Skullerud K (1983) Pleomorphic xanthoastrocytoma: report of 5 cases. Clin Neurol 2: 188–191

    Google Scholar 

  16. Hitselberger WE, Kernohan JW, Uihlein A (1961) Giant cell fibrosarcoma of the brain. Cancer 14: 841–852

    Google Scholar 

  17. Hoshino T, Wilson CB, Ellis WG (1975) Gemistocytic astrocytes in gliomas. An autoradiographic study. J Neuropathol Exp Neurol 34: 263–281

    Google Scholar 

  18. Jellinger K (1978) Glioblastoma multiforme: morphology and biology. Acta Neurochir (Wien) 42: 5–32

    Google Scholar 

  19. Jelsma R, Bucy PC (1967) The treatment of glioblastoma multiforme of the brain. J Neurosurg 27: 388–400

    Google Scholar 

  20. Johnson HA, Haymaker WE, Rubini JRet al (1960) A radioautographic study of a human brain and glioblastoma multiforme afterin vivo uptake of tritiated thymidine. Cancer 13: 636–642

    Google Scholar 

  21. Kepes JJ, Rubinstein LG, Eng LF (1979) Pleomorphic xanthoastrocytoma: a distinctive meningocerebral glioma of young subjects with relatively favourable prognosis. Cancer 44: 1839–1852

    Google Scholar 

  22. Manuelidis EE (1966) The fate of heterogeneously transplanted glioblastoma multiforme in the eye of the guinea pig. Am J Pathol 48: 65–89

    Google Scholar 

  23. Muller W, Dahmen HG (1978) Lymphocytes within glial cells (“emperipolesis”) in a case of a granular cell tumour. Acta Neuropathol (Berl) 44: 163–165

    Google Scholar 

  24. Palma L, Di Lorenzo N, Guidetti B (1978) Lymphocytic infiltrates in primary glioblastomas and recidivous gliomas. Incidence, fate and relevance to prognosis in 228 operated cases. J Neurosurg 49: 854–871

    Google Scholar 

  25. Goldman SA, Gandy SE (1987) Squamous cell carcinoma as a late complication of intracerebroventricular cyst. J Neurosurg 66: 618–620

    Google Scholar 

  26. Gluszcz A (1962) A cancer arising in a dermoid of the brain. A case report. J Neuropathol Exp Neurol 21: 383–387

    Google Scholar 

  27. Grant FC, Austin GM (1950) Epidermoids: clinical evaluation and surgical results. J Neurosurg 7: 190–198

    Google Scholar 

  28. Gross SW (1945) Radiographic visualization of an intracerebral dermoid cyst. J Neurosurg 2: 72–75

    Google Scholar 

  29. Guidetti B, Gagliardi FM (1977) Epidermoid and dermoid cyst. Clinical evaluation and late surgical results. J Neurosurg 47: 12–18

    Google Scholar 

  30. Hamel E, Frowein A, Karimi-Nejad A (1980) Intracranial intradural epidermoids and dermoids. Neurosurg Rev 3: 215–219

    Google Scholar 

  31. Hamer J (1980) Diagnosis by computerized tomography of intradural dermoid with spontaneous rupture of the cyst. Acta Neurochir (Wien) 51: 219–226

    Google Scholar 

  32. Handa J, Handa H, Mukai T (1979) Radiolucent intracranial dermoid cyst. Report of an unusual case. Neuroradiology 17: 211–214

    Google Scholar 

  33. Handa J, Okamoto K, Nakasu Y, Nakasu S, Nakano Y (1981) Computed tomography in intracranial epidermoid tumors with special reference to atypical features. Acta Neurochir (Wien) 8: 221–228

    Google Scholar 

  34. Hasegawa H, Biton S, Nakata M, Fujiwara M, Yasuda H (1981) Intracranial epidermoid mimicking meningioma. Surg Neurol 15: 372–374

    Google Scholar 

  35. Hori T, Numata H, Hokama Y, Muraoka K, Takami M, Saito Y (1983) Trigeminal pain caused by a parapontine epidermal cyst. Surg Neurol 19: 517–519

    Google Scholar 

  36. Hudgins RJ, Rhyner PA, Edwards MSB (1987) Magnetic resonance imaging of a pineal region dermoid. Surg Neurol 27: 558–562

    Google Scholar 

  37. Hwang WZ, Hasegawa T, Ito H, Shimoji T, Ikeda K, Yamamoto S (1985) Intracranial epidermoids-concerning the low absorption value on computerized tomography. Acta Neurochir (Wien) 78: 33–37

    Google Scholar 

  38. Imamura Y, Ninchoji T, Nakajima S, Uemura K (1982) Epidermoid tumor in the fourth ventricle, with particular reference to metrizamide CT cisternography findings. Surg Neurol 18: 444–447

    Google Scholar 

  39. Kazner E, Wende S, Grumme T, Lanksch W, Stochdorph O (1982) Computed tomography in intracranial tumors. Differential diagnosis and clinical aspects. Springer, Berlin Heidelberg New York, pp 320–322

    Google Scholar 

  40. Kirsch WM, Stears JC (1970) Radiographic identification and surgical excision of a epidermoid tumor of the pineal gland. J Neurosurg 33: 708–713

    Google Scholar 

  41. Kohno K, Sakaki S, Nakano K, Yano M, Matsuoka K (1984) Brain abscess secondary to intracranial extradural epidermoid cyst. Surg Neurol 22: 541–546

    Google Scholar 

  42. Laster D, Moody D, Ball M (1977) Epidermoid tumors with intraventricular and subarachnoid fat: report of two cases. Am J Roentgenol 128: 504–507

    Google Scholar 

  43. Leal O, Miles J (1978) Epidermoid cyst in the brain stem. Case report. J Neurosurg 48: 811–813

    Google Scholar 

  44. Lee SH, Delgado TE, Buchheit WA (1977) Intracranial dermoid tumor: diagnosis by computed tomography. A case report. Neurosurgery 1: 281–283

    Google Scholar 

  45. Lewis AJ, Cooper PW, Kassel EE, Schwartz ML (1983) Squamous cell carcinoma arising in a suprasellar epidermoid cyst. Case report. J Neurosurg 59: 538–541

    Google Scholar 

  46. Long JM, Kier EL, Schechter MM (1973) The radiology of epidermoid tumors in the cerebellopontine angle. Neuroradiology 6: 188–192

    Google Scholar 

  47. Mac Carty CS, Leavens ME, Love JG, Kernohan JW (1959) Dermoid and epidermoid tumors in the central nervous system of adults. Surg Gynecol Obstet 108: 191–198

    Google Scholar 

  48. Maravilla KR (1977) Intraventricular fat fluid level secondary to rupture of an intracranial dermoid cyst. Am J Roentgenol 128: 500–501

    Google Scholar 

  49. Martinez-Lage JF, Quinonez MA, Poza M, Puche A, Casas C, Costa RT (1985) Congenital epidermoid cyst over the anterior fontanelle. Child's Nerv Syst 1: 319–323

    Google Scholar 

  50. Mikhael MA, Mattar AG (1978) Intracranial pearly tumors: the roles of computed tomography, angiography and pneumo-encephalography. J Comput Assist Tomogr 2: 421–429

    Google Scholar 

  51. Mikhael MA (1982) Transient spasm of carotid siphon complicating ruptured cranial dermoid cyst. Radiology 144: 824

    Google Scholar 

  52. Mori K, Handa H, Moritake K, Takeuchi J, Nakano Y (1982) Suprasellar epidermoid. Neurochirurgia 25: 138–142

    Google Scholar 

  53. Nagashima C, Takahama M, Sakaguchi A (1982) Dense cerebellopontine epidermoid cyst. Surg Neurol 17: 172–177

    Google Scholar 

  54. Nosaka Y, Nagao S, Tabuchi K, Nishimoto A (1979) Primary intracranial epidermoid carcinoma. Case report. J Neurosurg 50: 830–833

    Google Scholar 

  55. Obrador S, Lopez-Zafra JJ (1969) Clinical features of the epidermoids of the basal cisterns of the brain. J Neurol Neurosurg Psychiatry 32: 450–454

    Google Scholar 

  56. Olivecrona H (1932) On suprasellar cholesteatomas. Brain 55: 122–134

    Google Scholar 

  57. Olivecrona H (1949) Cholesteatoma of the cerebello-pontine angle. Acta Psychiatr Neurol Scand 24: 639–643

    Google Scholar 

  58. Olson JJ, Beck DW, Crawford SC, Menezes AH (1987) Comparative evaluation of intracranial epidermoid tumors with computed tomography and magnetic resonance imaging. Neurosurgery 21: 357–360

    Google Scholar 

  59. Pannel BW, Hendrick BE, Hoffman HJ, Humphreys RP (1982) Dermoid cyst of the anterior fontanelle. Neurosurgery 10: 317–323

    Google Scholar 

  60. Rappaport ZH (1985) Epidermoid tumour of the cerebellopontine angle as a cause of trigeminal neuralgia. Neurochirurgia 8: 211–212

    Google Scholar 

  61. Rengachary S, Kishore PRS, Watanabe I (1978) Intradiploic epidermoid cyst of the occipital bone with torcular obstruction. J Neurosurg 48: 475–478

    Google Scholar 

  62. Rosario M, Becker DH, Conley FK (1981) Epidermoid tumours involving the fourth ventricle. Neurosurgery 9: 9–13

    Google Scholar 

  63. Rubinstein LJ (1972) Tumors of the central nervous system. Atlas of tumor pathology, Series 2, Fascicle 6. Armed Forces Institute of Pathology, Washington, DC, pp 288–292

    Google Scholar 

  64. Sabin HI, Bordi LT, Symon L (1987) Epidermoid cysts and cholesterol granulomas centered on the posterior fossa: twenty years of diagnosis and management. Neurosurgery 21: 798–805

    Google Scholar 

  65. Salazar J, Vaquero J, Saucedo G, Bravo G (1987) Posterior fossa epidermoid cysts. Acta Neurochir (Wien) 85: 34–39

    Google Scholar 

  66. Schubiger O, Valvanis A, Gessaga E (1983) Dense suprasellar epidermoid cyst. Neuroradiology 24: 269–271

    Google Scholar 

  67. Schulze H (1956) Zur Roentgendiagnostik der intrakraniellen Epidermoide. Fortschr Geb Roentgenstr Nuklearmed 84: 440–446

    Google Scholar 

  68. Scott M (1960) Epidermoid tumour (tumor perlée, cholesteatoma) of the brain: clinicopathologic study of two cases. J Neurosurg 17: 35–42

    Google Scholar 

  69. Tan TI (1972) Epidermoids and dermoids of the central nervous system (with two exceptional cases not represented in the literature). Acta Neurochir (Wien) 26: 13–24

    Google Scholar 

  70. Toglia JU, Netsky MG, Alexander E Jr (1965) Epithelial (epidermoid) tumors of the cranium. J Neurosurg 23: 384–393

    Google Scholar 

  71. Tytus JS, Pennybacker J (1956) Pearly tumors in relation to the central nervous system. J Neurol Neurosurg Psychiatry 19: 241–259

    Google Scholar 

  72. Ulrich J (1964) Intracranial epidermoids. A study on their distribution and spread. J Neurosurg 21: 1051–1058

    Google Scholar 

  73. Vion-Dury J, Vincitelli F, Jiddane M, Van Bunne Y, Rumeau C, Grisoli F, Salamon G (1987) MR imaging of epidermoid cysts. Neuroradiology 29: 333–338

    Google Scholar 

  74. Wakabayashi T, Tamaki N, Satoh H, Matsumoto S (1983) Epidermoid tumor presenting as painful tic convulsif. Surg Neurol 19: 244–246

    Google Scholar 

  75. Wakai S, Narita J, Hashimoto K, Nagai M (1983) Dermoid cyst communicating with the subarachnoid space and lateral ventricle: demonstration by metrizamide computed tomographic cisternography. Neurosurgery 13: 696–698

    Google Scholar 

  76. Yanai Y, Tsuji R, Ohmori S, Tatara, Kubota S, Nagashima C (1985) Malignant change in an intradiploic epidermoid: report of a case and review of the literature. Neurosurgery 16: 252–256

    Google Scholar 

  77. Zylak CJ, Childe AE, Ross RT, Parkinson D (1969) Lucent unilateral supratentorial dermoid cyst. Report of an unusual case. Am J Roentgenol 106: 329–332

    Google Scholar 

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Authors and Affiliations

  1. Department of Neurosurgery, Verona City Hospital, Verona, Italy

    G. Rubin M.D., R. Scienza, A. Pasqualin & R. Da Pian

  2. Department of Neuroradiology, Verona City Hospital, Verona, Italy

    L. Rosta

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  1. G. Rubin M.D.
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Rubin, G., Scienza, R., Pasqualin, A. et al. Craniocerebral epidermoids and dermoids. Acta neurochir 97, 1–16 (1989). https://doi.org/10.1007/BF01577734

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