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Behavioral characteristics and laboratory parameters in homo- and bisexual men in West Berlin: An evaluation of five years of testing and counselling on AIDS

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Summary

Sera of 1980 homo- and bisexual men who visited the Landesinstitut für Tropenmedizin Berlin (West) between April 1983 and December 1987 were tested for HIV antibodies; 24.3% were positive.

Of HIV-antibody-positive men, 78.9% reported both active and passive anal intercourse, 58.8%, rectal enemas, and 53.3%, use of butyl nitrite. There was a sexual partner with known positive HIV-antibody status or AIDS in 33.9%, and in 32.4% there was a history of sexual activity in the USA. In the year before the test, 18.8% had had more than 50 partners. All these behavioral characteristics were found to be significantly correlated to HIV antibodies.

We noted a substantial reduction of high-risk behavior from 1983 to 1987. The most important behavioral factor for HIV infection in 1983 and 1984 was sexual activity in the USA, and from 1984 to 1987, the numbers of lifetime partners.

Persons infected with HIV were significantly more often carriers of antibodies against HAV, HBV, CMV, EBV, and syphilis. Prevalence of antibodies against HIV, HAV, HBV, and syphilis increased with age, duration of homosexual practice, and the number of partners. Overall crude prevalence rates of HIV antibodies, anti-HBc, anti-HAV, and antibodies to syphilis declined during the observation period.

Clinical findings such as fever, oral lesions, and lymphadenopathy syndrome (LAS) were found to be highly indicative of HIV infection. Lower hemoglobin values, a reduced white cell count, and hyperimmunoglobulinemia were significantly more frequent in subjects with HIV antibodies.

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Abbreviations

AIDS:

Acquired immunodeficiency syndrome

CDC:

Centers for Disease Control

CMV:

Cytomegalovirus

DVV:

Deutsche Vereinigung zur Bekämpfung von Viruskrankheiten

EBV:

Epstein Barr virus

HAV:

Hepatitis A virus

HBV:

Hepatitis B virus

HIV:

Human immunodeficiency virus

HSV:

Herpes simplex virus

IgA:

Immunoglobulin A

IgG:

Immunoglobulin G

IgM:

Immunoglobulin M

LAS:

Lymphadenopathy syndrome

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Authors and Affiliations

  1. Landesinstitut für Tropenmedizin, Berlin

    S. Deininger, U. Laukamm-Josten & U. Bienzle

  2. Institut für Medizinische Statistik und Informationsverarbeitung, Freie Universität Berlin, Deutschland

    R. Müller & I. Guggenmoos-Holzmann

Authors
  1. S. Deininger
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  2. R. Müller
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  3. I. Guggenmoos-Holzmann
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  4. U. Laukamm-Josten
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  5. U. Bienzle
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Deininger, S., Müller, R., Guggenmoos-Holzmann, I. et al. Behavioral characteristics and laboratory parameters in homo- and bisexual men in West Berlin: An evaluation of five years of testing and counselling on AIDS. Klin Wochenschr 68, 906–913 (1990). https://doi.org/10.1007/BF01649037

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  • DOI: https://doi.org/10.1007/BF01649037

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