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Bowel cancer characteristics in patients with regional enteritis

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Abstract

We report 10 carcinomas in 8 patients with regional enteritis. Five of the cancers were in the ileum, 4 in the right colon, and 1 in the rectum. The visualized small bowel cancers appeared as benign strictures in small bowel involved by regional enteritis. Most were poorly differentiated. The colon cancers had a more typical radiographic appearance of malignancy. In some patients with small bowel cancer the malignancy was discovered only on histologic evaluation; the malignant nature of the lesion was not appreciated by radiography or gross examination at surgery.

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References

  1. Kerber GW, Frank PH: Carcinoma of the small intestine and colon as a complication of Crohn's disease: radiologic manifestations.Radiology 150:639–645, 1984

    Google Scholar 

  2. Gyde SN, Prior P, Macartney JC, Thompson H, Waterhouse JAH, Allan RN: Malignancy in Crohn's disease.Gut 21:1024–1029, 1980

    Google Scholar 

  3. Darke SG, Parks AG, Grogono JL, Pollock DJ: Adenocarcinoma and Crohn's disease. A report of 2 cases and analysis of the literature.Br J Surg 60:169–175, 1973

    Google Scholar 

  4. Traube J, Simpson S, Riddell RH, Levin B, Kirsner JB: Crohn's disease and adenocarcinoma of the bowel.Dig Dis Sci 25:939–944, 1980

    Google Scholar 

  5. Floch HF, Slattery LR, Hazzi CG: Carcinoma of the small intestine in regional enteritis. Presentation of a case and review of the literature.Am J Gastroenterol 70:520–527, 1978

    Google Scholar 

  6. Lightdale CJ, Sternberg SS, Posner G, Sherlock P: Carcinoma complicating Crohn's disease. Report of seven cases and review of the literature.Am J Med 59:262–268, 1975

    Google Scholar 

  7. Zinkin LD, Brandwein C: Adenocarcinoma in Crohn's colitis.Dis Colon Rectum 23:115–117, 1980

    Google Scholar 

  8. Collier PE, Turowski P, Diamond DL: Small intestinal adenocarcinoma complicating regional enteritis.Cancer 55:516–521, 1985

    Google Scholar 

  9. Fresko D, Lazarus SS, Dotan J, Reingold M: Early presentation of carcinoma of the small bowel in Crohn's disease (“Crohn's carcinoma”).Gastroenterology 82:783–789, 1982

    Google Scholar 

  10. Frank JD, Shorey BA: Adenocarcinoma of the small bowel as a complication of Crohn's disease.Gut 14:120–124, 1973

    Google Scholar 

  11. Hamilton SR: Colorectal carcinoma in patients with Crohn's disease.Gastroenterology 89:398–407, 1985

    Google Scholar 

  12. Greenstein AJ, Janowitz HD: Cancer in Crohn's disease. The danger of the by-passed loop.Am J Gastroenterol 64:122–124, 1975

    Google Scholar 

  13. Perrett AD, Truelove SC, Massarella GR: Crohn's disease and carcinoma of the colon.Br Med J 2:466–468, 1968

    Google Scholar 

  14. Warren R, Barwick KW: Crohn's colitis with carcinoma and dysplasia.Am J Surg Pathol 7:151–159, 1983

    Google Scholar 

  15. Craft CF, Mendelsohn G, Cooper HS, Yardley JH: Colonic “precancer” in Crohn's disease.Gastroenterology 80:578–584, 1981

    Google Scholar 

  16. Simpson S, Traube J, Riddell R: The histologic appearance of dysplasia (precarcinomatous change) in Crohn's disease of the small and large intestine.Gastroenterology 81:492–501, 1981

    Google Scholar 

  17. Valdes-Dapena A, Rudolph I, Hidayat A, Roth JLA, Laucks RB: Adenocarcinoma of the small bowel in association with regional enteritis.Cancer 37:2938–2947, 1976

    Google Scholar 

  18. Greenstein AJ, Sachar D, Pucillo A, Kreel I, Geller S, Janowitz HD, Aufses A Jr: Cancer in Crohn's disease after diversionary surgery. A report of seven carcinomas occurring in excluded bowel.Am J Surg 135:86–90, 1978

    Google Scholar 

  19. Victor DW Jr, Thompson H, Allan RN, Alexander-Williams J: Cancer complicating defunctioned Crohn's disease.Clin Oncol 8:163–165, 1982

    Google Scholar 

  20. Lavery IC, Jagelman DG: Cancer in the excluded rectum following surgery for inflammatory bowel disease.Dis Colon Rectum 25:522–524, 1982

    Google Scholar 

  21. Shorter RG: Risks of intestinal cancer in Crohn's disease.Dis Colon Rectum 26:686–689, 1983

    Google Scholar 

  22. Ginzburg L, Schneider KM, Dreizin DH, Levinson C: Carcinoma of the jejunum occurring in a case of regional enteritis.Surgery 39:347–351, 1956

    Google Scholar 

  23. Greenstein AJ, Sachar DB, Smith H, Janowitz HD, Aufses AH Jr: A comparison of cancer risk in Crohn's disease and ulcerative colitis.Cancer 48:2742–2745, 1981

    Google Scholar 

  24. Smith TR, Conradi H, Bernstein R, Greweldinger J: Adenocarcinoma arising in Crohn's disease: report of two cases.Dis Colon Rectum 23:498–503, 1980

    Google Scholar 

  25. Hawker PC, Gyde SN, Thompson H, Allan RN: Adenocarcinoma of the small intestine complicating Crohn's disease.Gut 23:188–193, 1982

    Google Scholar 

  26. Heathcote J, Knauer CM, Oakes D, Archibald RWR: Perforation of an adenocarcinoma of the small bowel affected by regional enteritis.Gut 21:1093–1096, 1980

    Google Scholar 

  27. Warren S, Sommers SC: Cicatrizing enteritis (regional ileitis) as a pathologic entity.Am J Pathol 24:475–501, 1948

    Google Scholar 

  28. Weedon DD, Shorter RG, Ilstrup DM, Huizenga KA, Taylor WF: Crohn's disease and cancer.N Engl J Med 289:1099–1103, 1973

    Google Scholar 

  29. Korelitz BI: Carcinoma of the intestinal tract in Crohn's disease: results of a survey conducted by the National Foundation for Ileitis and Colitis.Am J Gastroenterol 78:44–46, 1983

    Google Scholar 

  30. Greenstein AJ, Sachar DB, Smith H, Janowitz HD, Aufses AH Jr: Patterns of neoplasia in Crohn's disease and ulcerative colitis.Cancer 46:403–407, 1980

    Google Scholar 

  31. Sachar DB: New concepts of cancer.Mt Sinai J Med 50:133–137, 1983

    Google Scholar 

  32. Kim U, Aufses AH Jr, Kreel I: Malignant tumors associated with granulomatous enterocolitis.Am J Gastroenterol 63:66–70, 1975

    Google Scholar 

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Miller, T.L., Skucas, J., Gudex, D. et al. Bowel cancer characteristics in patients with regional enteritis. Gastrointest Radiol 12, 45–52 (1987). https://doi.org/10.1007/BF01885102

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  • DOI: https://doi.org/10.1007/BF01885102

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