Abstract
The anti-inflammatory efficacy of nepitrin (5,3′,4′-trihydroxy-6-methoxy flavone), a flavonoid, was investigated in both acute and chronic models of inflammation in rats. Nepitrin was found to possess significant anti-inflammatory activity in the exudative and proliferative phases of inflammation. This action of nepitrin could be due to its anti-bradykinin and anti-angiotensin action. Nepitrin also possessed anti-pyretic and weak analgesic activity. The study reveals that nepitrin may be useful as an anti-inflammatory and anti-arthritic agent.
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Agarwal, O.P. The anti-inflammatory action of nepitrin, a flavonoid. Agents and Actions 12, 298–302 (1982). https://doi.org/10.1007/BF01965393
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DOI: https://doi.org/10.1007/BF01965393