Skip to main content
SpringerLink
Log in

Bone metastases in Wilms' tumor—report of three cases and review of literature

  • Originals
  • Published:
Pediatric Radiology Aims and scope Submit manuscript

Abstract

Bone metastases are extremely rare in patients with classical Wilms' tumor (WT). We describe the clinical and radiologic features, treatment and outcome of three patients with WT (one with favorable histology and two with anaplasia) in whom bone metastases were detected at diagnosis or relapse. Bone metastases were documented by skeletal radiographs, computed tomography and/or bone scintigraphy. The patient with favorable histology WT had no evidence of pulmonary metastases and is now free of disease following aggressive chemotherapy and radiotherapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. The National Wilms' Tumor Study Committee (1991) Wilms' tumor: status report. J Clin Oncol 9:877

    Google Scholar 

  2. Marsden HB, Lennox EL, Lawler W, Kinnier-Wilson LM (1980) Bone metastases in childhood renal tumours. Br J Cancer 41:875

    PubMed  Google Scholar 

  3. Marsden HB, Lawler W, Kumar PM (1978) Bone metastasizing renal tumor of childhood: morphological and clinical features, and differences from Wilms' tumor. Cancer 42:1922

    PubMed  Google Scholar 

  4. Eklof O, Mortensson W, Sandstedt B, Ahstrom L (1984) Bone metastases in Wilms' tumor: occurrence and radiological appearance. Ann Radiol (Paris) 27:97

    Google Scholar 

  5. Bond JV, Martin EC (1975) Bone metastases in Wilms' tumour. Clin Radiol 26:103

    PubMed  Google Scholar 

  6. Ledlie EM, Mynors LS, Draper GJ, Gorbach PD (1970) Natural history and treatment of Wilms' tumour: an analysis of 335 cases occurring in England and Wales 1962–66. BMJ4:195

    PubMed  Google Scholar 

  7. Meister L, Uri A, Agrons G, Scher C (1993) Wilms' tumor bone metastases at diagnosis. Med Pediatr Oncol 21:446

    PubMed  Google Scholar 

  8. Levick RK, Steiner GM (1983) Skeletal survey in Wilms' tumour assessment. Ann Radiol (Paris) 26:235

    Google Scholar 

  9. Ebb DH, Kerasidis H, Vezina G, Packer RJ, Carabell S, Ivy P (1992) Spinal cord compression in widely metastatic Wilms' tumor. Paraplegia in two children with anaplastic Wilms' tumor. Cancer 69:2726

    PubMed  Google Scholar 

  10. Sumner TE, Crowe JE, Parker MD, White JP (1980) Solitary spinal metastasis from Wilms' tumor. Pediatr Radiol 9:175

    PubMed  Google Scholar 

  11. Lupi L, Bighi S, Limone GL, Merio L, Panzavolta R (1987) A case report of bone metastases in Wilms' tumor: diagnostic aspects and a review of the literature. Rays 12:61

    PubMed  Google Scholar 

  12. Garrett IR (1993) Bone destruction in cancer. Semin Oncol 20:4

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA

    S. Gururangan & J. A. Wilimas

  2. Department of Pediatrics, University of Tennessee, Memphis, Tennessee, USA

    S. Gururangan, J. A. Wilimas & B. D. Fletcher

  3. Department of Diagnostic Imaging, St. Jude Children's Research Hospital, 332 N. Lauderdale, 38101, Memphis, Tennessee, USA

    B. D. Fletcher

  4. Department of Radiology, University of Tennessee, Memphis, Tennessee, USA

    B. D. Fletcher

Authors
  1. S. Gururangan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. A. Wilimas
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. B. D. Fletcher
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

The work reported her was supported in part by the National Center Institute, Cancer Center Support (CORE) grant CA 21765 and by the American Lebanese Syrian Associated Charities (ALSAC)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gururangan, S., Wilimas, J.A. & Fletcher, B.D. Bone metastases in Wilms' tumor—report of three cases and review of literature. Pediatr Radiol 24, 85–87 (1994). https://doi.org/10.1007/BF02020158

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02020158

Keywords

Search

Navigation