Summary
Two patients with adult Still's disease and abnormal urinalysis underwent kidney biopsy 2 to 21 years after onset of the disease. Unexpectedly, mesangial glomerulonephritis was discovered. Even if a fortuitous association could not be excluded, the real prevalence of glomerular involvement in ASD should be determined by further studies in view of a potential immune complex pathogenesis of this condition.
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Larson, E.B., Featherstone, H.J., Petersdorf, R.G. Fever of undetermined origin: diagnosis and follow-up of 105 cases, 1970–1980. Medicine 1982, 61, 269–292.
Elkon, K.B., Hughes, G.R.V., Bywaters, E.G.L., Ryan, P.F.J., Inman, R.D., Bowley, N.B., James, M.P., Eady, R.A.J. Adult-onset Still's Disease: Twenty year follow-up and further studies of patients with active disease. Arthritis Rheum 1982, 25, 647–654.
Bujak, J.S., Aptekar, R.G., Decker, J.L., Wolff, S.M. Juvenile rheumatoid arthritis presenting in the adult as fever of unknown origin - Medicine 1973, 52, 431–444.
Del Paine, D.W., Leek, J.C. Still's arthritis in adults. Disease or syndrome? J Rheumatol 1983, 10, 758–761.
Bywaters, E.G.L. Still's disease in the adult. Ann Rheum Dis 1971, 30, 121–133.
Larson, E.B. Adult Still's Disease. Evolution of a clinical syndrome and diagnosis, treatment and follow-up of 17 patients. Medicine 1984, 63, 82–91.
Caroit, M., Mathieu, M., Kahn, M.F., De Seze. Maladie de Still de l'adulte et syndrome de Wissler Fanconi. Rev Rhum 1973, 40, 1–8.
Harrington, T.M., Moran, J.J., Davis, D.E. Amyloidosis in adult onset Still's Disease. J Rheumatol 1981, 8, 833–836.
Medsger, T.A., Christy, W.C. Carpal arthritis with ankylosis in late onset Still's Disease- Arthritis Rheum 1976, 19, 232–242.
Wendling, D., Humbert, P., Hory, B., Blanc, D., Dupond, J.L., Guidet, M. Le rein de la maladie de Still de l'adulte. Rev Rhum 1989, 56, 325–327.
Anttila, R. Renal involvement in juvenile rheumatoid arthritis. A Clinical and histopathological study. Acta Paediatr Scand. 1972, Suppl. 227, 1–73.
Schnitzer, T.J., Ansell, B.M. Amyloidosis in juvenile chronic polyarthritis. Arthritis Rheum 1977, 20, 245–252.
Clarkson, A.R., Woodroffe, A.J., Bannister, K.M., Lomax-Smith, J.D., Aarons, I. The syndrome of IgA nephropathy. Clin Nephrol 1984, 21, 7–14.
Jennette, C.J., Ferguson, A.L., Moore, M.A., Freeman, D.G. IgA nephropathy associated with sero-negative spondylarthropathies. Arthritis Rheum 1982, 25, 144–149.
Krothapalli, R., Neeland, B., Small, S., Duffy, W.B., Gyorkey, F., Senekjian, H.O. IgA nephropathy in a patient with ankylosing spondylitis and a solitary kidney. Clin Nephrol 1984, 21, 134–137.
Hordon, L.D., Sellars, L., Morley, A.R., Wilkinson, R., Thompson, M., Griffiths, D. Haematuria in rheumatoid arthritis: an association with mesangial glomerulonephritis. Ann Rheum Dis 1984, 43, 440–443.
Nicholls, K.M., Fairley, K.F., Dowling, J.P., Kincaid-Smith, P. The clinical course of mesangial IgA associated nephropathy in adults. Q J Med 1984, L III, 227–250.
Lammle, B., Steiger, U., Scharer, H., Schroder, E., Tholen, H. Morbus Still des Adulten-Bericht über 2 Fälle. Schweitz Med Wochenschr 1983, 113, 138–144.
Woodroffe, A.J., Gormly, A.A., McKenzie Wootton, A.M., Thomson, A.J., Sbymour, A.E., Clarkson, A.R. Immunologic studies in IgA nephropathy. Kidney Int 1980, 18, 366–374.
Wilton, J.M.A. Suppression by IgA of IgG mediated phagocytosis by human polymorphonuclear leucocytes. Clin Exp Immunol 1978, 34, 423–428.
Szabo, T., Szabo, M., Leukey, A., Szabo, J. Circulating immune complexes and phagocytic activity of polymorphonuclear cells in patients with glomerulonephritis. Clin Nephrol 1979, 12, 243–247.
Baart de la Faille Kuyper, E.H., Kater, L., Kuijten, R.H., Kooiker, C.J., Wagenaar, S.S., Van der Zouwen, P., Dorhout Mees, E.J. Occurrence of vascular IgA deposits in clinically normal skin of patients with renal disease. Kidney Int 1976, 9, 424–429.
Rotenstein, D., Gibbas, D., Majmudar, B., Chastain, E.A. Familial granulomatous arteritis with polyarthritis of juvenile onset. N Engl J Med 1982, 306, 86–90.
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Wendling, D., Hory, B. & Blanc, D. Adult Still's disease and mesangial glomerulonephritis. Report of two cases. Clin Rheumatol 9, 95–99 (1990). https://doi.org/10.1007/BF02030252
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DOI: https://doi.org/10.1007/BF02030252