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Pneumatosis intestinalis

Two case reports and a retrospective review of the literature from 1985 to 1995

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Summary

Pneumatosis intestinalis (PI) is characterized by subserosal or submucosal gas-filled cysts of the gastrointestinal tract. The course may be benign or may lead to the need for urgent surgery. Knowledge of the differential diagnosis, course, and treatment modalities are key in providing optimal care to patients who present with this entity. In this article, two cases of “benign” pneumatosis seen at our institution over a one-month period are presented, along with a retrospective review of the English literature from January 1985 to March 1995. Incidence, symptoms, gross and microscopic appearance, radiographic appearance, etiology, differential diagnosis and therapy are reviewed.

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References

  1. DuVernoi JG: Anatomische Beobachtungen der unter der aeussern und innern haut der Gedaerme eingeschlossenen luft. Phys Med Abhandl Acad Wissensch Petersb 2:182, 1783

    Google Scholar 

  2. Ecker JA, Williams RG, Clay KL: Pneumatosis cystoides intestinalis-bullous emphysema of the intestine. Am J Gastroenterol 56:125–136, 1971

    PubMed  Google Scholar 

  3. Koss LG: Abdominal gas cysts (pneumatosis cystoides intestinorum hominis): An analysis with a report of a case and a critical review of the literature. Arch Pathol 53:523–549, 1952

    Google Scholar 

  4. Sequeira W: Pneumatosis cystoides intestinalis in systemic sclerosis and other diseases. Semin Arthritis Rheum 19:269–277, 1990

    PubMed  Google Scholar 

  5. Knechtle SJ, Davidoff AM, Rice RP: Pneumatosis intestinalis: Surgical management and clinical outcome. Ann Surg 212:160–165, 1990

    PubMed  Google Scholar 

  6. Pieterse AS, Leong ASY, Rowland R: The mucosal changes and pathogenesis of pneumatosis cystoides intestinalis. Hum Pathol 16:683–688, 1985

    PubMed  Google Scholar 

  7. Keyting WS, McCarver RR, Kovarik JL, Daywitt AI: Pneumatosis intestinalis: A new concept. Radiology 76:733–741, 1961

    PubMed  Google Scholar 

  8. Galandiuk S, Fazio VW: Pneumatosis cystoides intestinalis: A review of the literature. Dis Colon Rectum 29:358–363, 1986

    PubMed  Google Scholar 

  9. Kay-Butler JJ: Interstitial emphysema of the cecum. Gut 3:267–268, 1962

    PubMed  Google Scholar 

  10. Sibbons P, Spitz L, van Velzen D: The role of lymphatics in the pathogenesis of pneumatosis in experimental bowel ischemia. J Pediatr Surg 27:339–343, 1992

    PubMed  Google Scholar 

  11. Cristl SU, Gibson GR, Murgatroyd PR, Scheppach W, Cummings JH: Impaired hydrogen metabolism in pneumatosis cystoides. Gastroenterology 104:392–397, 1993

    PubMed  Google Scholar 

  12. McKay LF, Eastwood MA, Brydon WG: Methane excretion in man: A study of breath, flatus, and faeces. Gut 26:69–74, 1985

    PubMed  Google Scholar 

  13. Hernanz-Schulman M, Kirkpatrick J Jr, Schwachman H, Herman T, Schulman G, Vawter GF: Pneumatosis intestinalis in cystic fibrosis. Radiology 160:497–499, 1986

    PubMed  Google Scholar 

  14. Yale CE, Balish E: The natural course of clostridium perfringens-induced pneumatosis cystoides intestinalis. J Med 23:279–288, 1992

    PubMed  Google Scholar 

  15. Andorsky RI: Pneumatosis cystoides intestinalis after organ transplantation. Am J Gastroenterol 85:189–194, 1990

    PubMed  Google Scholar 

  16. Berne TV, Halls JM: Intramural intestinal gas in adults. Surg Gynecol Obstet 156:479–484, 1983

    PubMed  Google Scholar 

  17. Day DL, Ramsay NKC, Letourneau JG: Pneumatosis intestinalis after bone marrow transplantation. AJR 151:85–87, 1988

    PubMed  Google Scholar 

  18. Bates FT, Gurney JW, Goodman LR, Santamaria JJ, Hansen RM, Ash RC: Pneumatosis intestinalis in bone marrow transplant patients: Diagnsosis on routine chest radiographs. AJR 152:991–994, 1989

    PubMed  Google Scholar 

  19. Benya EC, Sivit CJ, Quinones RR: Abdominal complications after bone marrow transplantation in children: Sonographic and CT findings. AJR 161:1023–1027, 1993

    PubMed  Google Scholar 

  20. King S, Shuckett B: Sonographic diagnosis of portal venous gas in two pediatric patients with benign pneumatosis intestinalis. Pediatr Radiol 22:577–578, 1992

    PubMed  Google Scholar 

  21. Karp DR, Kantor OS, Halverson JD, Atkinson JP: Successful management of catastrophic gastrointestinal involvement in polyarteritis nodosa. Arthritis Rheum 31:683–687, 1988

    PubMed  Google Scholar 

  22. Patel A, Creery D: Pneumatosis intestinalis in AIDS: An unreported complication. Br J Clin Pract 44:768–770, 1990

    PubMed  Google Scholar 

  23. Sivit CJ, Josephs SH, Taylor GA, Kushner DC: Pneumatosis intestinalis in children with AIDS. AJR 155:133–134, 1990

    PubMed  Google Scholar 

  24. Berne TV, Donovan AJ: Nonoperative treatment of perforated duodenal ulcer. Arch Surg 124:830–832, 1989

    PubMed  Google Scholar 

  25. Berdon WE, Grossman H, Baker DH, Mizrahi A, Barlow O, Blanc WA: Necrotizing enterocolitis in the premature infant. Radiology 83:879–887, 1964

    PubMed  Google Scholar 

  26. Grosfeld JL, Cheu H, Schlatter M, West KW, Rescorla FJ: Changing trends in necrotizing enterocolitis. Ann Surg 214:300–306, 1991

    PubMed  Google Scholar 

  27. Reynolds HL Jr, Gauderer MWL, Hrabovsky EE, Shurin SB: Pneumatosis cystoides intestinalis in children beyond the first year of life: Manifestations and management. J Pediatr Surg 26:1376–1380, 1991

    PubMed  Google Scholar 

  28. West KW, Rescorla FJ, Grosfeld JL, Vane DW: Pneumatosis intestinalis in children beyond the neonatal period. J Pediatr Surg 24:818–822, 1989

    PubMed  Google Scholar 

  29. Chabot VH, Slovis TL, Cullen M: Recurrent pneumatosis intestinalis in young infants. Pediatr Radiol 22:120–122, 1992

    PubMed  Google Scholar 

  30. Keene JG: Pneumatosis cystoides intestinalis and intramural intestinal. J Emerg Med 7:645–650, 1989

    PubMed  Google Scholar 

  31. Micklefield GH, Kuntz H, May B: Pneumatosis cystoides intestinalis: Case reports and review. Mater Med Pol 22:70–72, 1990

    PubMed  Google Scholar 

  32. Marshak RH, Lindner AE, Makalansky D: Pneumatosis cystoides coli. Gastrointest Radiol 2:85–89, 1977

    PubMed  Google Scholar 

  33. Moote DJ, Fried LA, LeBrun GP, Fraser DB: Pneumatosis coli: Is there a relationship with sigmoid colon redundancy. Gastrointest Radiol 14:79–82, 1989

    PubMed  Google Scholar 

  34. Finelli DS, McClary R, Cerda JJ: Pneumatosis cystoides intestinalis: Report of two cases and review of the literature. Mil Med 152:574–578, 1987

    PubMed  Google Scholar 

  35. Feczko PJ, Mezwa DG, Farah MC, White BD: Clinical significance of pneumatosis of the bowel wall. RadioGraphics 12:1069–1078, 1992

    PubMed  Google Scholar 

  36. Heng Y, Schuffler M, Haggit R, Rhorman CA: Pneumatosis intestinalis: A review. Am J Gastroenterol 90:1747–1758, 1995

    PubMed  Google Scholar 

  37. MacKenzie EP: Pneumatosis intestinalis: Review of the literature and report of 13 cases. Pediatrics 7:537–549, 1951

    PubMed  Google Scholar 

  38. Daly BD, Guthrie JA, Couse NF: Pneumoperitoneum without peritonitis. Postgrad Med J 67:999–1003, 1991

    PubMed  Google Scholar 

  39. Hoover EL, Cole GD, Mitchell LS, Adams CD, Hassett J: Avoiding laparotomy in nonsurgical pneumoperitoneum. Am J Surg 164:99–103, 1992

    PubMed  Google Scholar 

  40. Van Vugt AB, Sleeboom LA, Dekker WM, Mallens WMC, Ten Velde J: Giant cysts in diverticular disease of the sigmoid colon. Neth J Surg 37:183–186, 1985

    PubMed  Google Scholar 

  41. Spigelman AD, Williams CB, Ansell JK, Rutter KRP, Phillips RKS: Pneumatosis coli: A source of diagnostic confusion. Br J Surg 77:155, 1990

    PubMed  Google Scholar 

  42. Underwood JW, Finnis D, Scott W: Pneumatosis coli: A familial association. Br J Surg 65:64–65, 1978

    PubMed  Google Scholar 

  43. Calne RY: Gas cysts of the large bowel simulating multiple polyposis. Br J Surg 47:212–215, 1959

    PubMed  Google Scholar 

  44. Thomson WO, Gillespie G, Blumgart LH: The clinical significance of pneumatosis cystoides. Br J Surg 64:590–592, 1977

    PubMed  Google Scholar 

  45. Suarez V, Chesner IM, Price AB, Newman J: Pneumatosis cystoides intestinalis: Histological mucosal changes mimicking inflammatory bowel disease. Arch Pathol Lab Med 113:898–901, 1989

    PubMed  Google Scholar 

  46. Smerud MJ, Johnson CD, Stephens DH: Diagnosis of bowel infarction: A comparison of plain films and CT scans in 23 cases. AJR 154:99–103, 1990

    PubMed  Google Scholar 

  47. Seaman WB, Fleming RJ, Baker DH: Pneumatosis intestinalis of the small bowel. Semin Roentgenol 1:234–242, 1966

    Google Scholar 

  48. Hosomi N, Yoshioka H, Kuroda C, Sawai Y, Inoue E, Kadota T, Narumi Y, Kuriyama K, Fujita M, Iishi H, Ohtani T, Okuda S: Pneumatosis cystoides intestinalis: CT findings. Abdom Imaging 19:137–139, 1994

    PubMed  Google Scholar 

  49. Rabushka LS, Kuhlman JE: Pneumatosis intestinalis: Appearance on MR examination. Clin Imaging 18:258–261, 1994

    PubMed  Google Scholar 

  50. Mujahed Z, Evans JA: Gas cysts of the intestine (pneumatosis intestinalis). Surg Gynecol Obstet 107:151–160, 1958

    PubMed  Google Scholar 

  51. Vernacchia FS, Jeffrey RB, Laing FC, Wing VW: Sonographic recognition of pneumatosis intestinalis. AJR 145:51–52, 1985

    PubMed  Google Scholar 

  52. Sigel B, Machi J, Ramos JR, Serota AI, Robertson AL: Ultrasonic features of pneumatosis intestinalis. J Clin Ultrasound 13:675–678, 1985

    PubMed  Google Scholar 

  53. Von Maluski FC: Pneumatosis masquerading as abdominal free air. Postgrad Med 83:101–105, 1988

    Google Scholar 

  54. Kosloske AM, Musemeche CA, Ball WS Jr, Ablin DS, Bhattacharyya N: Necrotizing enterocolitis: Value of radiographic findings to predict outcome. AJR 151:771–774, 1988

    PubMed  Google Scholar 

  55. Sisk PB: Gas in the portal venous system. Radiology 77:103–107, 1961

    Google Scholar 

  56. Cho KC, Simmons MZ, Baker SR, Cappell MS: Spontaneous dissection of air into the transverse mesocolon during double contrast barium enema. Gastrointest Radiol 15:76–77, 1990

    PubMed  Google Scholar 

  57. Kou SW, Chai CY, Chou CK, Chan HM: Pneumatosis cystoides intestinalis arising in jejunal diverticular disease: Report of a case and a suggestion to its pathogenesis. Kaohsiung J Med Sci 8:486–494, 1992

    Google Scholar 

  58. DeMarino GB, Sumkin JH, Leventhal R, Van Thiel DH: Pneumatosis intestinalis and pneumoperitoneum after sclerotherapy. AJR 151:953–954, 1988

    PubMed  Google Scholar 

  59. Marshak RH, Blum SD, Eliasoph J: Pneumatosis involving the left side of the colon. JAMA 161:1626–1628, 1956

    Google Scholar 

  60. McCollister DL, Hammerman HJ: Air, air everywhere: pneumatosis cystoides coli after colonoscopy. Gastrointest Endosc 36:75–76, 1990

    Google Scholar 

  61. Collins CD, Blanshard C, Cramp M, Gazzard B, Gleeson JA: Case report: Pneumatosis intestinalis occurring in association with cryptosporidiosis and HIV infection. Clin Radiol 46:410–411, 1992

    PubMed  Google Scholar 

  62. Jensen R, Gutnik SH: Pneumatosis cystoides intestinalis: A complication of colonoscopic polypectomy. SD J Med 44:177–179, 1991

    Google Scholar 

  63. Smith CD, Sarr MG: Clinically significant pneumatosis intestinalis with postoperative enteral feedings by needle catheter jejunostomy: A unusual complication. JPEN 15:328–331, 1991

    Google Scholar 

  64. Thomas VIL, Cohen AJ, Omiya B, McKenzie R, Tominga G: pneumatosis intestinalis associated with needle catheter jejunostomy tubes: CT findings and implications. J Comput Assist Tomogr 16:418–419, 1992

    PubMed  Google Scholar 

  65. Fukuya T, Brown BP, Lu CC: Midgut volvulus as a complication of intestinal malrotation in adults. Dig Dis Sci 38:438–444, 1993

    PubMed  Google Scholar 

  66. Yang CJC, Lu CH, Murakami J, Franken EA Jr: General case of the day: Midgut volvulus with necrotic small bowel. Radio-Graphics 7:605–607, 1987

    Google Scholar 

  67. Schwarz DA, Stark M, Wright J: Segmental colonic gangrene: A previously unreported complication of adult hemolytic uremic syndrome. Surgery 116:107–110, 1994

    PubMed  Google Scholar 

  68. Alpern MB, Glazer GM, Francis IR: Ischemic or infarcted bowel: CT findings. Radiology 166:149–152, 1988

    PubMed  Google Scholar 

  69. Buffo GC, Deitch JS: Pneumatosis intestinalis in a patient with polyarteritis nodosa. Gastrointest Radiol 11:286–288, 1986

    PubMed  Google Scholar 

  70. Balthazar EJ, Stern J: Necrotizing candida enterocolitis in AIDS: CT features. J Comput Assist Tomogr 18:298–300, 1994

    PubMed  Google Scholar 

  71. Lund EC, Han SY, Holley HC, Berland LL: Intestinal ischemia: Comparison of plain radiographic and computed tomographic findings. RadioGraphics 8:1083, 1988

    PubMed  Google Scholar 

  72. Caudill JL, Rose BS: The role of computed tomography in the evaluation of pneumatosis intestinalis. J Clin Gastroenterol 9:223–226, 1987

    PubMed  Google Scholar 

  73. Sato A, Yamaguchi K, Nakajima T: A new health problem due to trichloroethylene: Pneumatosis cystoides intestinalis. Arch Environ Health 42:144–147, 1987

    PubMed  Google Scholar 

  74. Ogata M, Kihara T, Kamoi R, Taguchi T, Oda J, Kenmotsu K: A report of a worker suffering from pneumatosis cystoides. Ind Health 26:179–182, 1988

    PubMed  Google Scholar 

  75. Yamaguchi K, Shirai T, Shimakura K, Akamatsu T, Nakama H, Kono K, Sakato M, Shigeno T, Furuta S, Nakajima T, Sato A: Pneumatosis cystoides intestinalis and trichloroethylene exposure. Am J Gastroenterol 80:753–757, 1985

    PubMed  Google Scholar 

  76. Fleming LE: Unusual occupational gastrointestinal and hepatic disorders. Occup Med 7:433–448, 1992

    PubMed  Google Scholar 

  77. Ritchie AJ, Carson JG, Humphreys WG: Encysted pneumatocele: A complication of diverticular disease. Br J Surg 78:683, 1991

    PubMed  Google Scholar 

  78. John A, Dickey K, Fenwick J, Sussman B, Beeken W. Pneumatosis intestinalis in patients with crohn's disease. Dig Dis Sci 37:813–817, 1992

    PubMed  Google Scholar 

  79. Galandiuk S, Fazio VW, Petras RE: Pneumatosis cystoides intestinalis in Crohn's disease: Report of two cases. Dis Colon Rectum 28:951–956, 1985

    PubMed  Google Scholar 

  80. Tjon A, Tham RTO, Vlasveld LT, Willemze R: Gastrointestinal complications of cytosine-arabinoside chemotherapy. AJR 154:99–103, 1990

    PubMed  Google Scholar 

  81. Sachse RE, Burke GW, Jonas M, Milgrom M, Miller J: Benign pneumatosis intestinalis with subcutaneous emphysema in liver transplant recipient. Am J Gastroenterol 85:876–879, 1990

    PubMed  Google Scholar 

  82. Jackson JE, Thomas AMK: The case of the bloated nurse. Br J Radiol 60:721–722, 1987

    PubMed  Google Scholar 

  83. Goulet JR, Hurtubise M, Senécal JL: Retropneumoperitoneum and pneumatosis intestinalis in 2 patients with mixed connective tissue disease and the overlap syndrome. Clin Exp Rheumatol 6:81–85, 1988

    PubMed  Google Scholar 

  84. Pruitt RE, Tumminello VV, Reveille JD: Pneumatosis cystoides intestinalis and benign pneumoperitoneum in a patient with antinuclear antibody negative systemic iupus erythematosus. J Rheumatol 15:1575–1577, 1988

    PubMed  Google Scholar 

  85. Kobayashi T, Kobayashi M: Response to octreotide of intestinal pseudoobstruction and pneumatosis cystoides intestinalis associated with progressive systemic sclerosis. Inter Med 32:607–609, 1993

    Google Scholar 

  86. Decrop E, Ponette E, Baert AL, Verberckmoes R, Kerremans R, Geboes K: Preoeprative radiologic diagnosis of acute necrotizing enteritis in systemic lupus erythematosis. J Belge Radiol 73:31–35, 1990

    PubMed  Google Scholar 

  87. Wilkinson MM: Small intestinal complications in progressive systemic sclerosis. Gastroenterol Nurs 15:50–53, 1992

    PubMed  Google Scholar 

  88. van Leeuwen JCJ, Nossent JC: Pneumatosis intestinalis in mixed connective tissue disease. Neth J Med 40:299–304, 1992

    PubMed  Google Scholar 

  89. Stafford-Brady FJ, Kahn HJ, Ross TM, Russell ML: Advanced scleroderma bowel: Complications and management. J Rheumatol 15:869–874, 1988

    PubMed  Google Scholar 

  90. Pahlman L, Enander L: Pneumatosis intestinalis in young patients. Acta Chir Scand 154:547–548, 1988

    PubMed  Google Scholar 

  91. Tak PP, van Duinen CM, Bun P, Eulderink F, Kreuning J, Gooszen HG, Lamers CBHW: Pneumatosis cystoides intestinalis in intestinal pseudoobstruction: Resolution after therapy with metronidazole. Dig Dis Sci 37:949–954, 1992

    PubMed  Google Scholar 

  92. Mueller GP, Cassady CI, Dietrich RB, Pais MJ, Warden MJ: Pediatric case of the day: Occult child abuse (manifesting with pneumotowsis intestinalis and portal venous gas). Radio-Graphics 14:928–930, 1994

    Google Scholar 

  93. Chippindale AJ, Desai S: Two unusual cases of pneumatosis coli. Clin Radiol 43:180–182, 1991

    PubMed  Google Scholar 

  94. Case WG, Hall R: Surgical treatment of pneumatosis coli. Ann R Coll Surg Engl 67:368–369, 1985

    PubMed  Google Scholar 

  95. Pun YLW, Russell DM, Taggart GJ, Barraclough DRE: Penumatosis intestinalis and pneumoperitoneum complicating mixed connective tissue disease. Br J Rheumatol 30:146–149, 1991

    PubMed  Google Scholar 

  96. Berglund S: Roentgen diagnosis of pneumatosis cystoides intestinorum hominis. Acta Radiol 20:401–404, 1939

    Google Scholar 

  97. Cabrera GE, Scopelitis E, Cuellar ML, Silveira LH, Mena H, Espinoza LR: Pneumatosis cystoides intestinalis in systemic lupus with intestinal vasculitis: Treatment with high dose prednisone. Clin Rheumatol 13:312–316, 1994

    PubMed  Google Scholar 

  98. Lang TJ: Gastroenterol vasculitis and pneumatosis intestinalis due to systemic lupus erythematosis: Successful treatment with pulse intravenous cyclophosphamide. Am J Med 85:555–558, 1988

    PubMed  Google Scholar 

  99. Johansson K, Lindström E: Treatment of obstructive pneumatosis coli with endoscopic sclerotherapy: Report of a case. Dis Colon Rectum 34:94–96, 1991

    PubMed  Google Scholar 

  100. Elberg JJ: Oxygen therapy for pneumatosis coli. Acta Chir Scand 151:399–400, 1985

    PubMed  Google Scholar 

  101. Kelly BE, Cooper GG, Mills JOM: Pneumoperitoneum due to PCI in a patient with a strangulated femoral hernia. Br J Clin Pract 47:272, 1993

    PubMed  Google Scholar 

  102. Grieve DA, Unsworth IP: Pneumatosis cystoides intestinalis: An experience with hyperbaric oxygen treatment. Aust NZ J Surg 61:423–426, 1991

    Google Scholar 

  103. Jauhonen P, Lehtola J, Karttunen T: Treatment of pneumatosis tosis coli with metronidazole. Dis Colon Rectum 30:800–801, 1987

    PubMed  Google Scholar 

  104. Sidhu S, Flamm S, Chopra S: Pneumatosis cystoides intestinalis: An incidental finding in a patient with AIDS and cryptosporidial diarrhea. Am J Gastroenterol 89:1578–1579, 1994

    PubMed  Google Scholar 

  105. Lipton J, Patterson B, Mustard R, Tejpar I, Fyles G, Meharchand J, Messner H: Pneumatosis intestinalis with free air mimicking intestinal perforation in a bone marrow transplant patient. Bone Marrow Transplant 14:323–326, 1994

    PubMed  Google Scholar 

  106. Yeager AM, Kanof ME, Kramer SS, Jones B, Saral R, Alake AM, Santos GW: Pneumatosis intestinalis in children after allogeneic bone marrow transplantation. Pediatr Radiol 17:18–22, 1987

    PubMed  Google Scholar 

  107. Paraf F, Vulser C, Guillemain R, Amrein C, Bloch F, Bruneval P: Pneumatosis cystoides intestinalis after cardiac transplantation: Report of three cases. Am J Gastroenterol 85:1429–1431, 1990

    Google Scholar 

  108. Sackier JM, Smith EJ, Wood CB: Cystic pneumatosis in coeliac disease. Gut 29:852–855, 1988

    PubMed  Google Scholar 

  109. Khouri MR, Levine MS, Dabezies M, Saul SH: Benign pneumoperitoneum in a patient with celiac sprue. J Clin Gastroenterol 11:70–72, 1989

    PubMed  Google Scholar 

  110. Holt RW, Dekker J: Gastric pneumatosis intestinalis associated with cholangiocarcinoma. South Med J 79:79–80, 1986

    PubMed  Google Scholar 

  111. Christensen LA, Schmidt EB, Mortenson PB, Hcjhus JH: Pneumatosis intestinalis in a patient on chronic hemodialysis treatment. Nephrol Dial Transplant 4:745–747, 1989

    PubMed  Google Scholar 

  112. Luks FI, Chung MA, Brandt ML, Hertecant J, Roy CC, Blanchard H, Bensoussan AL: Pneumatosis and pneumoperitoneum in chronic idiopathic intestinal pseudoobstruction. J Pediatr Surg 26:1384–1386, 1991

    PubMed  Google Scholar 

  113. Wang S, Goodman B: Pneumatosis coli producing colo-colic intussusception: A case report. Australas Radiol 32:483–486, 1988

    PubMed  Google Scholar 

  114. Mack P: Pneumo-retroperitoneum associated with pneumatosis cystoides intestinalis. Ann Acad Med Singapore 17:600–602, 1988

    PubMed  Google Scholar 

  115. Longo WE, Ballantyne GH, Graham AJ: Pneumatosis cystoides intestinalis: Presentation as an acute abdomen. J Clin Gastroenterol 9:571–573, 1987

    PubMed  Google Scholar 

  116. Soutter DI, Paloschi GB, Prentice RS: Pneumatosis cystoides intestinalis simulating malignant colonic obstruction. Can J Surg 28:272–273, 1985

    PubMed  Google Scholar 

  117. Siskind BN, Burrell MI, Klein ML, Princenthal RA: Toxic dilation in Crohn's disease with cCT correlation. J Comput Assist Tomogr 9:193–195, 1985

    PubMed  Google Scholar 

  118. Pasquier E, Wattiaux MJ, Peigney N: First case of pneumatosis cystoides intestinalis in adult. J Rheumatol 20:499–503, 1993

    PubMed  Google Scholar 

  119. Fahal AH, Baraka OZ, El-Lider AM: Pneumatosis cystoid intestinalis: A case report. East Afr Med J 71:401–402, 1994

    PubMed  Google Scholar 

  120. Tobias R, Coleman S, Helman CA: Pneumatosis coli simulating hepatomegaly. Am J Gastroenterol 80:146–149, 1985

    PubMed  Google Scholar 

  121. Vijayaraghavan SB: Sonographic features of pneumatosis of the small bowel. J Clin Ultrasound 18:579–581, 1990

    PubMed  Google Scholar 

  122. Janssen DA, Kalayogla M, Sollinger HW: Pneumatosis cystoides intestinalis following lactulose and lactulose and steroid treatment in a liver transplant patient with an intermittently enlarged scrotum. Transplant Proc 19:2949–2952, 1987

    PubMed  Google Scholar 

  123. Bohler A, Speich R, Russi EW, Meyenberger C, Weder W: Pneumatosis intestinalis and active cytomegalovirus. Chest 107:582, 1995

    PubMed  Google Scholar 

  124. Mannes GPM, de Boer WJ, van der Jagt EJ, Meinesz AF, Meuzelarr JJ, van der Bij W: Pneumatosis intestinalis and active cytomegaloviral infection after lung transplantation. Chest 105:929–930, 1994

    PubMed  Google Scholar 

  125. Lanspa SJ, Liu MW, Jenkins HJ: Giant bulla in pneumatosis cystoides intestinalis. J Clin Gastroenterol 10:437–440, 1988

    PubMed  Google Scholar 

  126. Fick TE, Van Oorschot FHAM, Mallens WMC, Kitslaar PJEHM: Pneumoperitoneum without peritonitis. Neth J Surg 40:152–154, 1988

    PubMed  Google Scholar 

  127. Zern RT, Clarke-Pearson DL: Pneumatosis intestinalis associated with enteral feeding by catheter jejunostomy. Obstet Gynecol 65:81S-83S, 1985

    PubMed  Google Scholar 

  128. Balmaseda MT Jr, Lagattuta FP, Tugaoen JF: Pneumatosis cystoides intestinalis in quadraplegia: A case report. Arch Phys Med Rehabil 68:563–565, 1987

    PubMed  Google Scholar 

  129. Van Son WJ, Van der Woude FJ, van der Jagt EJ, Donker AJM, Meijer S, Sloff MJH, The TH, Tegzess AM, van dr Slike LB: Pneumatosis intestinalis in patients after cadaveric kidney transplantation: Possible relationship with an active cytomegalovirus infection. Proc Eur Dial Transplant Assoc Eur Ren Assoc 21:936–940, 1985

    PubMed  Google Scholar 

  130. Murphy BJ, Weinfeld A: Innocuous pneumatosis intestinalis of the right colon in renal transplant recipients: Report of three cases. Dis Colon Rectum 30:816–819, 1987

    PubMed  Google Scholar 

  131. Ammons MA, Bauling PC, Weil R III: Pneumatosis cystoides intestinalis with pneumoperitoneum in renal transplant patients on cyclosporine and prednisone. Transplant Proc 18:1868–1870, 1986

    PubMed  Google Scholar 

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Authors and Affiliations

  1. From the Departments of Gastroenterology, Radiology, and Epidemiology, University of North Carolina School of Medicine, 27559, Chapel Hill, North Carolina

    R. Michael Boerner MD, PhD, Daniel B. Fried MPH, David M. Warshauer MD &  Kim Isaacs MD, PhD

  2. Department of Radiology, Mallinckrodt Institute of Radiology, Washington Medical Center, Saint Louis, Missouri

    R. Michael Boerner MD, PhD, Daniel B. Fried MPH, David M. Warshauer MD &  Kim Isaacs MD, PhD

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Boerner, R.M., Fried, D.B., Warshauer, D.M. et al. Pneumatosis intestinalis. Digest Dis Sci 41, 2272–2285 (1996). https://doi.org/10.1007/BF02071412

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