Skip to main content
Log in

Is the benign joint hypermobility syndrome benign?

  • Originals
  • Published:
Clinical Rheumatology Aims and scope Submit manuscript

Summary

Over a period of two years, joint hypermobility was identified in 95 female and 19 male patients who attended rheumatology and rehabilitation units in Ismailia city. Pauciarticular pains referring to large and medium-sized joints was their most frequent complaint. Clinical diagnosis of carpal and/or tarsal tunnel syndromes was made in 45.6% of patients, and various forms of soft tissue rheumatism were evident in 73% of them. On radiologic evaluation of the involved joints, 60.5% of the examined patients showed significant degenerative lesions. The most prominent finding in the study, however, was the aggregation of varieties of articular and extra-articular abnormalities in the same patient. Extra-articular features included high frequencies of occurrence of varicose veins, piles and uterine prolapse among other abnormalities. Thus, results of the study lend support to the view that joint hypermobility predisposes to several articular and nonarticular lesions and raise serious questions about the reputable benignity of the syndrome.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Hollister, D.W., Byers, P.H., Holbrook, K.A. Genetic disorders of collagen metabolism. Adv Hum Genet 1982, 12, 1.

    PubMed  Google Scholar 

  2. Pyertiz, R.E., McKusick, V.A. The Marfan syndrome: Diagnosis and management. N Engl J Med 1979, 300, 772.

    PubMed  Google Scholar 

  3. Kirk, J.A., Ansell, B.M., Bywaters, E.G. The hypermobility syndrome: Musculoskeletal complaints associated with generalized hypermobility. Ann Rheum Dis 1967,26, 419.

    PubMed  Google Scholar 

  4. Wood, P.H.N. Is hypermobility a discrete entity? ProcR Soc Med, 1971 64, 690.

    Google Scholar 

  5. Graham, R., Pitcher, E.D., Gabell, A., Harvey, W. A clinical and echocardiographic study of patients with hypermobility syndrome. Ann Rheum Dis 1981, 40, 541.

    PubMed  Google Scholar 

  6. Jaffe, M., Tirosh, E., Cohen, A., Taub, Y. Joint mobility and motor development. Arch Dis Child 1988, 63 (2), 159.

    PubMed  Google Scholar 

  7. Marshman, D., Percy, J., Fielding, I., Delbridge, L. Rectal prolapse: relationship with joint mobility. Aust NZ J Surg 1987, 57 (11), 827.

    Google Scholar 

  8. Gedalia, A., Person, D.A., Brewer, E.J. Jr., Giannini, E.H. Hypermobility of the joints in juvenile episodic arthritis/arthralgia. J Pediatr 1985, 107(6), 873.

    PubMed  Google Scholar 

  9. Scott, D., Bird, H., Wright, V. Joint laxity leading to osteoarthrosis. Rheumatol Rehabil 1979, 18, 167.

    PubMed  Google Scholar 

  10. Bird, H.A., Tribe, C.R., Bacon, P.A. Joint hypermobility leading to osteoarthrosis and chondrocalcinosis. Ann Rheum Dis 1978, 37, 203.

    PubMed  Google Scholar 

  11. Carter, C.O., Wilkinson, J. Persistent joint laxity and congenital dislocation of the hip. J Bone Joint Surg (Br) 1964, 46(B), 40.

    Google Scholar 

  12. Beighton, P., Solomon, L., Saskolne, C.L. Articular mobility in an African population. Ann Rheum Dis 1973, 32, 413.

    PubMed  Google Scholar 

  13. March, L.M., Francis, H., Webb, J. Benign joint hypermobility with neuropathies: documentation and mechanism of median, sciatic and common peroneal nerve compression. Clin Rheumatol 1988, 7 (1), 35.

    PubMed  Google Scholar 

  14. Handler, C.E., Child, A., Light, N.D., Dorrance, D.E. Mitral valve prolapse, aortic compliance and skin collagen in joint hypermobility syndrome. Br Heart J 1985, 54 (5), 501.

    PubMed  Google Scholar 

  15. Thornton, J.G., Hill, J., Bird, H.A. Complications of pregnancy and benign familial joint hyperlaxity. Ann Rheum Dis 1988, 47, 228.

    PubMed  Google Scholar 

  16. Biro, F., Gewanter, H., Baum, J. The hypermobility syndrome. Pediatr 1983, 72 (5), 701.

    Google Scholar 

  17. Graham, R., Child A. Mitral valve prolapse (letter). Br Med J 1984, 289, 317.

    Google Scholar 

  18. Klemp, P., Stevens, J.E., Isacs, S. A hypermobility study in ballet dancers. J Rheumatol 1984, 11, 692.

    PubMed  Google Scholar 

  19. Lewkonia, R.M., Ansell, B.M. Articular hypermobility simulating chronic rheumatic disease. Arch Dis Childhood 1983, 58, 988.

    Google Scholar 

  20. Wynne-Davis, R. Acetabular dysplasia and familial joint laxity: two etiological factors in congenital dislocation of the hip. J Bone Joint Surg (Br) 1970, 52(B), 704.

    Google Scholar 

  21. Moran, H.M., Hall, M.A., Barr, A., Ansell, B.M. Spinal mobility in the adolescence. Rheumatol Rehabil 1976, 18, 181.

    Google Scholar 

  22. McCarty, D.J. (ed.). Arthritis and Allied Disorders. Philadelphia, Lea and Febiger 1985, pp. 1377–1442.

    Google Scholar 

  23. Graham, R. Joint hypermobility: clinical aspects. Proc R Soc Med 1971, 64, 692.

    PubMed  Google Scholar 

  24. El-Rawi, Z.S., El-Rawi, Z.T. Joint hypermobility in women with genital prolapse. Lancet 1982, June 26, 1439.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

El-Shahaly, H.A., El-Sherif, A.K. Is the benign joint hypermobility syndrome benign?. Clin Rheumatol 10, 302–307 (1991). https://doi.org/10.1007/BF02208695

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02208695

Key words

Navigation